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home  Discovery Services Compound Selectivity Profiling Custom Protein Development Contact Information         The Cost-Effective Approach to Discovery in a Time Sensitive Manner SignalChem scientists have gained an extensive experience in the development and production of cellular signaling proteins. Our scientists have the capabilities to undertake the custom development of the client’s desired target as well as the expertise to develop the appropriate assay systems to assess the respective biological activity of the target. Our scientists have developed proprietary methodologies to produce large quantities of extremely pure recombinant proteins that possess high specific activity without compromising the fidelity of the active site. In general, SignalChem’s active protein kinases represent the full-length human clone and do not possess any activating mutations as these mutations do not occur in vivo. In addition, our scientists have an extensive experience in developing the appropriate assay systems for any biological target. In particular, SignalChem’s validated assay systems can be used in high throughput format to identify potent inhibitor compounds. The identified inhibitor compounds can be counter-screened against SignalChem’s expanding panel of diverse protein kinase and protein phosphatase targets. Using these methodologies, SignalChem can identify potent leads as well as determine the selectivity profile of the compound for our clients. To learn more about how SignalChem can increase your research efficiency in a cost effective manner, contact us with your specific requirements.

Promotion   Recieve 20% off the regular price on all Compound Profiling Projects over $1000US. Select from over 210 Active Kinases & Phosphatases in Screen. Majority of targets are full-length, free of activating mutations and are of human origin. more information           Popular Products   By Item: AKT1, Active AKT3, Active 14-3-3ζ Protein GSK3β, Active GSK3β, Active PDK1, Active AKT2, Active 14-3-3θ Protein PDKtide SRC, Active By Category: Wnt Signaling SAPK/JNK Pathway Akt/PKB Pathway p38 Pathway Tyr Kinases Diabetes MAPK/ERK Pathway Ser/Thr Kinases Apoptosis Lipid Signaling

Contact SignalChem [toll free]: 1-866-9 KINASE (54-6273) [phone]: 1-604-232-4600 [fax]: 1-604-232-4601 [email]: info@signalchem.com

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