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Compound Selectivity Profiling Custom Protein Development Contact Information

The Cost-Effective Approach to Discovery in a Time Sensitive Manner

SignalChem scientists have gained an extensive experience in the development and production of cellular signaling proteins. Our scientists have the capabilities to undertake the custom development of the client’s desired target as well as the expertise to develop the appropriate assay systems to assess the respective biological activity of the target.

Our scientists have developed proprietary methodologies to produce large quantities of extremely pure recombinant proteins that possess high specific activity without compromising the fidelity of the active site. In general, SignalChem’s active protein kinases represent the full-length human clone and do not possess any activating mutations as these mutations do not occur in vivo.

In addition, our scientists have an extensive experience in developing the appropriate assay systems for any biological target. In particular, SignalChem’s validated assay systems can be used in high throughput format to identify potent inhibitor compounds. The identified inhibitor compounds can be counter-screened against SignalChem’s expanding panel of diverse protein kinase and protein phosphatase targets. Using these methodologies, SignalChem can identify potent leads as well as determine the selectivity profile of the compound for our clients.

To learn more about how SignalChem can increase your research efficiency in a cost effective manner, contact us with your specific requirements.


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AMPK Best Seller Sale

Introducing Active Phosphodiesterases

Order 1 mg of our selected Active Kinases* for $2100

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Select from over 285 Active Kinases, Active Phosphatases & Active Phosphodiesterases in Screen. Majority of targets are full-length, free of activating mutations and are of human origin.


	Popular Products



By Item:
	AKT1, Active

	GSK3β, Active

	AKT2, Active

	PDK1, Active

	Akt(PKB) Substrate

	AKT2, Active

	AKT3, Active

	PI3K (p110α/p85α), Active

	GSK3α, Active

	AKT2, Unactive


By Category:
	p38 Pathway

	JNK/SAPK Pathway

	Phosphodiesterases

	NfkB Pathway

	JAK/STAT Pathway

	Apoptosis/Autophagy

	PKA/PKC Pathway

	Cellular Stress

	ERK/MAPK Pathway

	Angiogenesis

Contact SignalChem
[toll free]: 1-866-9 KINASE (54-6273)
[phone]: 1-604-232-4600
[fax]: 1-604-232-4601

[email]: info@signalchem.com