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CAMK1β, Active (C08-10G)

Catalog Number Pack Size Price (US)
C08-10G-05 5 μg  $195 
C08-10G-10 10 μg  $285 
C08-10G-20 20 μg  $495 

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Description: Recombinant full-length mouse CAMK1beta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
 
Genbank Number: NM_032960
 
Sequence: Full-length
 
Expression System: Sf9 insect cells using baculovirus
 
Tag: N-terminal GST tag
 
Species: Mouse

Storage and Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~64 kDa

Gene Aliases : Punc; Bstk3; CaMKlb2; caMKlb1; Pnck

Scientific Background: CAMKIβ is thought to be involved in a variety of developmental processes including development of the central nervous system (1). CAMKIβ2, an isoform of mCAMKIβ, is mainly present in the nervous system, including brain, spinal cord, trigeminal ganglion, and retina. Within the CNS, the expression of CAMKIβ2 is detected in the mantle zone suggesting its possible involvement in the differentiation of neurons (2).

References: 
1. Gardner,H.P. et al: Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase. Genomics 63 (2), 279-288 (2000)

2. Ueda,T. et al: Distribution and intracellular localization of a mouse homologue of Ca2+/calmodulin-dependent protein kinase Ibeta2 in the nervous system. J. Neurochem. 73 (5), 2119-2129 (1999).


  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.



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