Isoform Specific Antibodies


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SignalChem's Isoform Specific Antibodies


Access to highly validated biological reagents is of paramount importance in research and drug discovery effort. Isoform-specific antibodies specifically recognize one of the many isoforms of a given protein in a cell and are purified using affinity chromatography incorporating the immobilized protein target onto a rigid matrix.


Isoform-specific antibodies are tested for sensitivity and specificity using various immunological techniques such as Western blot and immunoprecipitation. As an example, AKT exists as AKT1, AKT2 and AKT3 and the AKT3 isoform-specific antibody from SignalChem specifically recognizes only the AKT3 isoform and not AKT1 and AKT2.


Isoform-specific antibodies can be used for multiple applications such as western blotting, immunoprecipitation, immunocytochemistry, ELISA and other immunological technologies. Isoform-specific antibodies can also be beneficial in the treatment of various human diseases such as cancer, diabetes and neurological disorders where they can have impact on only the defective isoform of a protein target without impacting the other normal protein isoforms.


SignalChem offers a unique line of highly validated isoform specific antibodies that specifically recognize the intended target with the greatest affinity. All of these antibodies are counter-screened against the recombinant isoforms of the appropriate protein that SignalChem offers as a means of ensuring true specificity.


Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Anti-AKT3 A18-63R Rabbit WB
Anti-AMPK alpha 1 P47-63R Rabbit WB
Anti-CAMK1 C07-60M Mouse, IgG1, 5H8 WB
Anti-CHK2 C48-60M Mouse, IgG1, 7F9 WB
Anti-ERK1 M29-60M Mouse, IgG1, E32 WB, IP
Anti-ERK1 M29-60BM Mouse, IgG1, E19 WB, IP
Anti-GSK3 alpha G08-63R Rabbit WB
Anti-GSK3 beta G09-60M Mouse, IgG1, 6C2 WB
Anti-HSP90 beta H36-63R Rabbit WB
Anti-JAK2 J02-63R Rabbit WB
Anti-JNK1 M33-63R Rabbit WB
Anti-JNK2 M34-60M Mouse, IgG2, 2G12 WB, IP
Anti-MEK1 M02-60M Mouse, IgG1, 7F1 WB, IP
Anti-MEK2 M03-63R Rabbit WB
Anti-p38 alpha M39-63R Rabbit WB
Anti-p38 beta M36-63R Rabbit WB
Anti-p38 gamma M37-63R Rabbit WB
Anti-PAK1 P02-63R Rabbit WB
Anti-PKC delta P64-63R Rabbit WB
Anti-PKC delta P64-63CR Rabbit WB
Anti-PKC mu P72-63R Rabbit WB
Anti-PKC theta P74-63R Rabbit WB
Anti-SMAD2 S11-63R Rabbit WB
Anti-STAT1 beta S52-63R Rabbit WB
Anti-STAT3 S54-63R Rabbit WB
Anti-STAT3 S54-63BR Rabbit WB, IP
Anti-STAT4 S55-63R Rabbit WB
Anti-STAT5 S56-63R Rabbit WB
Anti-STAT5 S56-63BR Rabbit WB
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Anti-AKT3 A18-63R Rabbit WB
Anti-AMPK alpha 1 P47-63R Rabbit WB
Anti-CAMK1 C07-60M Mouse, IgG1, 5H8 WB
Anti-CHK2 C48-60M Mouse, IgG1, 7F9 WB
Anti-ERK1 M29-60M Mouse, IgG1, E32 WB, IP
Anti-ERK1 M29-60BM Mouse, IgG1, E19 WB, IP
Anti-GSK3 alpha G08-63R Rabbit WB
Anti-GSK3 beta G09-60M Mouse, IgG1, 6C2 WB
Anti-HSP90 beta H36-63R Rabbit WB
Anti-JAK2 J02-63R Rabbit WB
Anti-JNK1 M33-63R Rabbit WB
Anti-JNK2 M34-60M Mouse, IgG2, 2G12 WB, IP
Anti-MEK1 M02-60M Mouse, IgG1, 7F1 WB, IP
Anti-MEK2 M03-63R Rabbit WB
Anti-p38 alpha M39-63R Rabbit WB
Anti-p38 beta M36-63R Rabbit WB
Anti-p38 gamma M37-63R Rabbit WB
Anti-PAK1 P02-63R Rabbit WB
Anti-PKC delta P64-63R Rabbit WB
Anti-PKC delta P64-63CR Rabbit WB
Anti-PKC mu P72-63R Rabbit WB
Anti-PKC theta P74-63R Rabbit WB
Anti-SMAD2 S11-63R Rabbit WB
Anti-STAT1 beta S52-63R Rabbit WB
Anti-STAT3 S54-63R Rabbit WB
Anti-STAT3 S54-63BR Rabbit WB, IP
Anti-STAT4 S55-63R Rabbit WB
Anti-STAT5 S56-63R Rabbit WB
Anti-STAT5 S56-63BR Rabbit WB
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application
Isoform Specific Antibodies Product Listing Found: Total 29 Products Matching Isoform Specific Antibodies
Product Name Catalog Number Host Cited Application


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active GTPases/ATPases Active GTPases/ATPases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinase Mutants Active Kinase Mutants
Enzymes Active Kinases Active Kinases
Enzymes Active Lipid Kinases Active Lipid Kinases
Enzymes Active Methyltransferases Active Methyltransferases
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Enzymes Active Proteases Active Proteases
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Biochemical Compounds
Biochemical Compounds Epigenetic Enzyme Activators Epigenetic Enzyme Activators
Biochemical Compounds Epigenetic Enzyme Inhibitors Epigenetic Enzyme Inhibitors
Biochemical Compounds Kinase Activators Kinase Activators
Biochemical Compounds Kinase Inhibitors Kinase Inhibitors
Biochemical Compounds Phosphatase Inhibitors Phosphatase Inhibitors
Biochemical Compounds siRNA Controls siRNA Controls
Biochemical Compounds siRNA Sets siRNA Sets
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferases Acetyl/Methyltransferases
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylases Deacetylase/Demethylases
Signaling Proteins Dihydropyrimidinase Dihydropyrimidinase
Signaling Proteins Dioxygenases Dioxygenases
Signaling Proteins Fructose Kinases Fructose Kinases
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Kinase Mutant Proteins Kinase Mutant Proteins
Signaling Proteins Kinase Protein Kinase Protein
Signaling Proteins Lysyl Oxidases Lysyl Oxidases
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Phospholipase C Proteins Phospholipase C Proteins
Signaling Proteins Superoxide Dismutase Superoxide Dismutase
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Lipid Substrates Lipid Substrates
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Discovery Services
Compound Selective Profiling Compound Selectivity Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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