Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Kinase Assay, Western Blot
Molecular Weight: ~58 kDa
Gene Aliases: CAMKB, CAM2, CAMK2, MGC29528
Scientific Background: CAMK2β belongs to the serine/threonine protein kinase family and to the type II multifunctional Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2β showed wide tissue and cell distribution, and one of CAMK2β variant predominated in adult brain (1). The ratio of CAMK2α and CAMK2β protein levels were inversely related during activity in hippocampal neurons (2). CAMK2β is a prominent kinase in the central nervous system and may function in long-term potentiation and neurotransmitter release.
References:
1. Tombes, R. M. et al: Identification of novel human tumor cell-specific CaMK-II variants. Biochim. Biophys. Acta 1355: 281-292, 1997.
2. Thiagarajan, T. C. Et al: Alpha- and beta-CaMKII: inverse regulation by neuronal activity and opposing effects on synaptic strength. Neuron 36: 1103-1114, 2002.
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Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet. |
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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The CAMK2 beta, Active product can be utilized in the following research areas, but not limited to:
Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases
| Product Type |
Product Name |
Catalog Number |
Application |
Pack Sizes |
| Enzymes |
CAMK1, Active |
C07-10G |
Kinase Assay, Western Blot |
View CAMK1, Active
|
| Enzymes |
CAMK1 beta, Active |
C08-10G |
Kinase Assay, Western Blot |
View CAMK1 beta, Active
|
| Enzymes |
CAMK1 delta, Active |
C09-10G |
Kinase Assay, Western Blot |
View CAMK1 delta, Active
|
| Enzymes |
CAMK1 gamma, Active |
C10-11G |
Kinase Assay, Western Blot |
View CAMK1 gamma, Active
|
| Enzymes |
CAMK2 alpha, Active |
C11-10G |
Kinase Assay, Western Blot |
View CAMK2 alpha, Active
|
| Enzymes |
CAMK4, Active |
C15-10G |
Kinase Assay, Western Blot |
View CAMK4, Active
|
| Enzymes |
CAMKK1, Active |
C17-10G |
Kinase Assay, Western Blot |
View CAMKK1, Active
|
| Enzymes |
CAMKK2, Active |
C18-10G |
Kinase Assay, Western Blot |
View CAMKK2, Active
|
| Signaling Reagents |
Autocamtide 2 |
A15-58 |
Kinase Assay |
View Autocamtide 2
|
| Signaling Reagents |
Kinase Assay Buffer I |
K01-09 |
Kinase Assay |
View Kinase Assay Buffer I
|
| Enzymes |
CAMK2 gamma, Active |
C14-10G |
Kinase Assay, Western Blot |
View CAMK2 gamma, Active
|
| Signaling Proteins |
CaMKPase Protein |
P06-34G |
Western Blot |
View CaMKPase Protein
|
| Enzymes |
CAMK2 delta, Active |
C13-10G |
Kinase Assay, Western Blot |
View CAMK2 delta, Active
|
| Signaling Proteins |
Calmodulin 1 Protein |
C01-30H |
Kinase Assay, Western Blot |
View Calmodulin 1 Protein
|
| Signaling Reagents |
Ca2+/Calmodulin Solution, 10x |
C02-39 |
Kinase Assay |
View Ca2+/Calmodulin Solution, 10x
|
| Enzymes |
CAMK1 gamma, Active |
C10-10BG |
Kinase Assay, Western Blot |
View CAMK1 gamma, Active
|