ERK1 Active Enzymes Active Kinases


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ERK1, Active (M29-10U)
Catalog Number Pack Size Price (USD)  
ERK1, Active M29-10U-05 5 ug $205   ERK1, Active Add to Cart
ERK1, Active M29-10U-10 10 ug $295   ERK1, Active Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length, tag-free human ERK1 was by baculovirus in Sf9 insect cells and activated by active MEK1in vitro.
Tag: Tag-free
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_002746
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~44 kDa

Gene Aliases : MAPK3; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; MGC20180

Scientific Background: ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines (1). Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

References: 
1. Boulton, TG. et al: Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase. Biochemistry. 1991 Jan 8;30(1):278-86.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




ERK1, Active Research Areas

The ERK1, Active product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases



ERK1, Active Related Products Found: Total 49 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Signaling Proteins ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Signaling Proteins MEK1, Unactive M02-14H Kinase Assay, Western Blot View MEK1, Unactive
Enzymes RSK1, Active R15-10G Kinase Assay, Western Blot View RSK1, Active
Enzymes RSK2, Active R17-10G Kinase Assay, Western Blot View RSK2, Active
Enzymes RSK3, Active R16-10G Kinase Assay, Western Blot View RSK3, Active
Enzymes HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
Signaling Proteins RAS Protein R05-30G Kinase Assay, Western Blot View RAS Protein
Enzymes MST4, Active M59-10G Kinase Assay, Western Blot View MST4, Active
Enzymes TIE 2, Active T04-11G Kinase Assay, Western Blot View TIE 2, Active
Enzymes MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Enzymes MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Enzymes AMPK (A1/B1/G1), Active P47-10H Kinase Assay, Western Blot View AMPK (A1/B1/G1), Active
Enzymes COT, Active M16-11G Kinase Assay, Western Blot View COT, Active
Enzymes MINK1, Active M53-11G Kinase Assay, Western Blot View MINK1, Active
Enzymes RAF1 (EE), Active R01-13G Kinase Assay, Western Blot View RAF1 (EE), Active
Enzymes MEK2, Active M03-10G Kinase Assay, Western Blot View MEK2, Active
Enzymes AMPK (A2/B1/G1), Active P48-10H Kinase Assay, Western Blot View AMPK (A2/B1/G1), Active
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Enzymes AMPK (A1/B1/G2), Active P55-10H Kinase Assay, Western Blot View AMPK (A1/B1/G2), Active
Enzymes MEK1, Active M02-10G Kinase Assay, Western Blot View MEK1, Active
Signaling Reagents MBP Protein M42-51N Kinase Assay, Western Blot View MBP Protein
Enzymes HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Signaling Proteins Tau-352 Protein T03-54N Kinase Assay, Western Blot View Tau-352 Protein
Signaling Proteins Tau-381 Protein T04-54N Kinase Assay, Western Blot View Tau-381 Protein
Signaling Proteins Tau-383 Protein T05-54N Kinase Assay, Western Blot View Tau-383 Protein
Signaling Proteins Tau-410 Protein T06-54N Kinase Assay, Western Blot View Tau-410 Protein
Signaling Proteins Tau-412 Protein T07-54N Kinase Assay, Western Blot View Tau-412 Protein
Signaling Proteins Tau-441 Protein T08-54N Kinase Assay, Western Blot View Tau-441 Protein
Signaling Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Signaling Proteins COT, Unactive M16-15G Kinase Assay, Western Blot View COT, Unactive
Signaling Proteins ELK1 Protein E64-30G Kinase Assay, Western Blot View ELK1 Protein
Signaling Proteins MEK2, Unactive M03-14G Kinase Assay, Western Blot View MEK2, Unactive
Enzymes AMPK (A1/B1/G3), Active P56-10H Kinase Assay, Western Blot View AMPK (A1/B1/G3), Active
Enzymes AMPK (A1/B2/G1), Active P50-10H Kinase Assay, Western Blot View AMPK (A1/B2/G1), Active
Enzymes RSK4, Active R20-10G Kinase Assay, Western Blot View RSK4, Active
Enzymes TOPK, Active T14-10G Kinase Assay, Western Blot View TOPK, Active
Antibodies Anti-ERK1 M29-60M WB, IP View Anti-ERK1
Antibodies Anti-ERK1 M29-60CM IP View Anti-ERK1
Antibodies Anti-ERK1 M29-60BM WB, IP View Anti-ERK1
Signaling Proteins 14-3-3 epsilon Protein Y75-30N Western Blot View 14-3-3 epsilon Protein
Antibodies Anti-ERK1/2 M29-60EM WB View Anti-ERK1/2
Signaling Proteins ERK1, Unactive M29-14G Kinase Assay, Western Blot View ERK1, Unactive
Enzymes TEC, Active T03-10G Kinase Assay, Western Blot View TEC, Active
Enzymes ERK1, Active M29-10G Kinase Assay, Western Blot View ERK1, Active
Enzymes MNK1, Active M54-10G Kinase Assay, Western Blot View MNK1, Active
Enzymes ERK5, Active M32-10G Kinase Assay, Western Blot View ERK5, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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