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Catalog Number |
Pack Size |
Price (USD) |
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| LYN B, Active |
L13-10G-05 |
5 ug |
$205 |
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Add to Cart |
| LYN B, Active |
L13-10G-10 |
10 ug |
$295 |
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Add to Cart |
| LYN B, Active |
L13-10G-BULK |
BULK |
CONTACT US |
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* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
| Tag: |
GST tag |
| Expression System: |
Sf9 insect cells using baculovirus |
| Species: |
Human |
| Sequence: |
Full length |
| Genbank Number: |
BC059394
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Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Kinase Assay, Western Blot
Molecular Weight: ~85 kDa
Gene Aliases : JTK8; FLJ26625; p65
Scientific Background: LYN is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues (1). LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase.
References:
1. Yamanashi, Y. et al: The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck. Mol Cell Biol. 1987 Jan;7(1):237-43.
2. Yamanashi, Y. et al: Association of B cell antigen receptor with protein tyrosine kinase Lyn. Science. 1991 Jan 11;251(4990):192-4.
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Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet. |
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. |
LYN B, Active Research Areas
The LYN B, Active product can be utilized in the following research areas, but not limited to:
AKT/PKB Pathway, Cancer, Cardiovascular Disease, Cellular Stress, Cytoplasmic Tyrosine Kinases, Inflammation
| Product Type |
Product Name |
Catalog Number |
Application |
Pack Sizes |
| Enzymes |
BLK, Active |
B02-10G |
Kinase Assay, Western Blot |
View BLK, Active
|
| Enzymes |
FGR, Active |
F10-10G |
Kinase Assay, Western Blot |
View FGR, Active
|
| Enzymes |
HCK, Active |
H02-11G |
Kinase Assay, Western Blot |
View HCK, Active
|
| Enzymes |
BRK, Active |
P94-10G |
Kinase Assay, Western Blot |
View BRK, Active
|
| Enzymes |
SRC, Active |
S19-10G |
Kinase Assay, Western Blot |
View SRC, Active
|
| Enzymes |
LCK, Active |
L03-10G |
Kinase Assay, Western Blot |
View LCK, Active
|
| Signaling Reagents |
Kinase Assay Buffer I |
K01-09 |
Kinase Assay |
View Kinase Assay Buffer I
|
| Enzymes |
FRK, Active |
F14-11G |
Kinase Assay, Western Blot |
View FRK, Active
|
| Enzymes |
ZAP70, Active |
Z02-10G |
Kinase Assay, Western Blot |
View ZAP70, Active
|
| Signaling Reagents |
SRC Substrate |
S30-58 |
Kinase Assay |
View SRC Substrate
|
| Enzymes |
ABL1, Active |
A03-11H |
Kinase Assay, Western Blot |
View ABL1, Active
|
| Enzymes |
ABL2, Active |
A04-11H |
Kinase Assay, Western Blot |
View ABL2, Active
|
| Enzymes |
SRC, Active |
S19-18G |
Kinase Assay, Western Blot |
View SRC, Active
|
| Signaling Proteins |
BCR Protein |
B01-35G |
Western Blot |
View BCR Protein
|
| Enzymes |
LYN A, Active |
L13-18G |
Kinase Assay, Western Blot |
View LYN A, Active
|
| Signaling Reagents |
Kinase Dilution Buffer I |
K21-09 |
Kinase Assay |
View Kinase Dilution Buffer I
|
| Enzymes |
ABL1, Active |
A03-18H |
Kinase Assay, Western Blot |
View ABL1, Active
|
| Signaling Proteins |
FYN C, Unactive |
F15-14G |
Kinase Assay, Western Blot |
View FYN C, Unactive
|
| Enzymes |
FYN A, Active |
F15-10G |
Kinase Assay, Western Blot |
View FYN A, Active
|
| Enzymes |
YES1, Active |
Y01-10G |
Kinase Assay, Western Blot |
View YES1, Active
|