LYN B Active Enzymes Active Kinases


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LYN B, Active (L13-10G)

Catalog Number Pack Size Price (USD)  
LYN B, Active L13-10G-05 5 ug $205   LYN B, Active Add to Cart
LYN B, Active L13-10G-10 10 ug $295   LYN B, Active Add to Cart
LYN B, Active L13-10G-BULK BULK CONTACT US  
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Bulk Pricing for LYN B, Active

Product Data Sheet(s)




Description: Recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: BC059394
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~85 kDa

Gene Aliases : JTK8; FLJ26625; p65

Scientific Background: LYN is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues (1). LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase.

References
1. Yamanashi, Y. et al: The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck. Mol Cell Biol. 1987 Jan;7(1):237-43.

2. Yamanashi, Y. et al: Association of B cell antigen receptor with protein tyrosine kinase Lyn. Science. 1991 Jan 11;251(4990):192-4.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




LYN B, Active Research Areas

The LYN B, Active product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, Cancer, Cardiovascular Disease, Cellular Stress, Cytoplasmic Tyrosine Kinases, Inflammation



LYN B, Active Related Products Found: Total 20 Related Products
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Enzymes SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Enzymes LCK, Active L03-10G Kinase Assay, Western Blot View LCK, Active
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Enzymes FRK, Active F14-11G Kinase Assay, Western Blot View FRK, Active
Enzymes ZAP70, Active Z02-10G Kinase Assay, Western Blot View ZAP70, Active
Signaling Reagents SRC Substrate S30-58 Kinase Assay View SRC Substrate
Enzymes ABL1, Active A03-11H Kinase Assay, Western Blot View ABL1, Active
Enzymes ABL2, Active A04-11H Kinase Assay, Western Blot View ABL2, Active
Enzymes SRC, Active S19-18G Kinase Assay, Western Blot View SRC, Active
Signaling Proteins BCR Protein B01-35G Western Blot View BCR Protein
Enzymes LYN A, Active L13-18G Kinase Assay, Western Blot View LYN A, Active
Signaling Reagents Kinase Dilution Buffer I K21-09 Kinase Assay View Kinase Dilution Buffer I
Enzymes ABL1, Active A03-18H Kinase Assay, Western Blot View ABL1, Active
Signaling Proteins FYN C, Unactive F15-14G Kinase Assay, Western Blot View FYN C, Unactive
Enzymes FYN A, Active F15-10G Kinase Assay, Western Blot View FYN A, Active
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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