PAK4 Active Enzymes Active Kinases


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PAK4, Active (P05-10BG)
Catalog Number Pack Size Price (USD)  
PAK4, Active P05-10BG-05 5 ug $205   PAK4, Active Add to Cart
PAK4, Active P05-10BG-10 10 ug $295   PAK4, Active Add to Cart
PAK4, Active P05-10BG-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length human PAK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_005884
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~90 kDa

Gene Aliases: None

Scientific Background: PAK4 is a recently identified member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, cdc 42 and Rac. PAK4 belongs to the Group II PAKs which also includes PAK5 and PAK6. PAK4 has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells.

References: 
1. Jaffer, Z M. et al: p21-activated kinases: three more join the Pak. Int J Biochem Cell Biol. 2002 Jul;34(7):713-7.

2. Qu, J. et al: Activated PAK4 regulates cell adhesion and anchorage-independent growth. Mol Cell Biol. 2001 May;21(10):3523-33.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




PAK4, Active Research Areas

The PAK4, Active product can be utilized in the following research areas, but not limited to:

Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases



PAK4, Active Related Products Found: Total 11 Related Products
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Enzymes PAK7, Active P07-10G Kinase Assay, Western Blot View PAK7, Active
Signaling Proteins PAK1, Unactive P02-14G Western Blot View PAK1, Unactive
Enzymes PAK6, Active P06-10G Kinase Assay, Western Blot View PAK6, Active
Signaling Proteins PAK1, Unactive P02-17G Kinase Assay, Western Blot View PAK1, Unactive
Enzymes PAK1/CDC42, Active P02-10G Kinase Assay, Western Blot View PAK1/CDC42, Active
Signaling Reagents PAKtide P08-58 Kinase Assay View PAKtide
Enzymes PAK3, Active P04-10G Kinase Assay, Western Blot View PAK3, Active
Antibodies Anti-PAK1 P02-63R WB View Anti-PAK1
Enzymes PKN2/PRK2, Active P71-10G Kinase Assay, Western Blot View PKN2/PRK2, Active
Signaling Proteins PAK2 Protein P03-34G Western Blot View PAK2 Protein


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
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Enzymes Active Phosphatases Active Phosphatases
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Extracellular Ligands
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Signaling Proteins
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Discovery Services
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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