PP1A Active Enzymes Active Phosphatases


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PP1A, Active (P13-20G)
Catalog Number Pack Size Price (USD)  
PP1A, Active P13-20G-05 5 ug $205   PP1A, Active Add to Cart
PP1A, Active P13-20G-10 10 ug $295   PP1A, Active Add to Cart
PP1A, Active P13-20G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length human PP1A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_002708
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Phosphatase Assay, Western Blot

Molecular Weight: ~62 kDa

Gene Aliases: LAR

Scientific Background: PP1A is a serine/threonine specific protein phosphatase family which is involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. PP1A is one of the three catalytic subunits of protein phosphatase 1 (PP1) (1). PP1A functions as a suppressor of learning and memory and as a potential mediator of cognitive decline during aging (2).PP1A is also play a main role in splice site selection and is an important regulator of cardiac function.

References: 
1. Cohen, P.et.al: Protein phosphatases come of age. J. Biol. Chem. 264: 21435-21438, 1989.

2. Genoux, D. et.al: Protein phosphatase 1 is a molecular constraint on learning and memory. Nature 418: 970-975, 2002.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




PP1A, Active Research Areas

The PP1A, Active product can be utilized in the following research areas, but not limited to:

Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Metabolic Disorder, Phosphatases, Ser/Thr Kinases



PP1A, Active Related Products Found: Total 6 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
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Enzymes PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
Enzymes PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
Signaling Proteins PP2Abeta Protein P17-34G Western Blot View PP2Abeta Protein
Signaling Proteins PP2B Protein P18-34G Western Blot View PP2B Protein


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
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Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
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Signaling Reagents
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Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
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Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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