Active Phosphatases


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SignalChem's Active Phosphatases

Protein phosphatases are a group of enzymes that are found ubiquitously and are responsible for the dephosphorylation of various proteins and lipids in cells. In general, protein phosphatases antagonize the actions of protein kinases and this is an important control mechanism utilized by cells to regulate protein function.


Cellular proteins and lipids undergo cycles of phosphorylation and dephosphorylation reactions as part of post translational modification (ptm) in response to various stimuli such as growth factors, cytokines and hormones. Protein phosphatases regulate the phosphorylation state of many important signaling molecules and are a key regulatory component in signal transduction pathways involved in the control of cell growth, proliferation, differentiation and transformation.


In general, protein phosphatases display broad substrate specificity and can dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within proteins. Protein phosphatases have been identified as "druggable" targets and are being aggressively pursued for the treatment of various human diseases such as diabetes and cancer.


SignalChem offers a diverse and comprehensive range of active protein phosphatases and these can be tested using phosphorylated peptides, proteins or lipids as substrate.


Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
CDC25A, Active C04-20G Phosphatase Assay, Western Blot View CDC25A, Active
CDC25B, Active C04-20BG Phosphatase Assay, Western Blot View CDC25B, Active
CDC25C, Active C04-20CG Phosphatase Assay, Western Blot View CDC25C, Active
DUSP22 (MKPX), Active D22-20G Phosphatase Assay, Western Blot View DUSP22 (MKPX), Active
PP1A, Active P13-20G Phosphatase Assay, Western Blot View PP1A, Active
PP1B, Active P14-20G Phosphatase Assay, Western Blot View PP1B, Active
PP2Aalpha, Active P16-20G Phosphatase Assay, Western Blot View PP2Aalpha, Active
PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
PTEN, Active P23-20G Phosphatase Assay, Western Blot View PTEN, Active
PTPN1 (PTP1B), Active P28-20G Phosphatase Assay, Western Blot View PTPN1 (PTP1B), Active
PTPN11 (SHP2), Active P38-21G Phosphatase Assay, Western Blot View PTPN11 (SHP2), Active
PTPN12 (PTP-PEST), Active P39-21G Phosphatase Assay, Western Blot View PTPN12 (PTP-PEST), Active
PTPN13 (FAP-1), Active P40-21G Phosphatase Assay, Western Blot View PTPN13 (FAP-1), Active
PTPN2 (TC-PTP), Active P29-20G Phosphatase Assay, Western Blot View PTPN2 (TC-PTP), Active
PTPN6 (SHP1), Active P33-20G Phosphatase Assay, Western Blot View PTPN6 (SHP1), Active
PTPN7 (LC-PTP), Active P34-20G Phosphatase Assay, Western Blot View PTPN7 (LC-PTP), Active
PTPRA (LRP), Active P48-21G Phosphatase Assay, Western Blot View PTPRA (LRP), Active
PTPRC (CD45), Active P50-21H Phosphatase Assay, Western Blot View PTPRC (CD45), Active
PTPRC (CD45), Active P50-21BG Phosphatases Assay, Western Blot View PTPRC (CD45), Active
PTPRE, Active P52-21G Phosphatase Assay, Western Blot View PTPRE, Active
PTPRF (LAR), Active P53-21G Phosphatase Assay, Western Blot View PTPRF (LAR), Active
PTPRS (PTP- sigma), Active P64-21G Phosphatase Assay, Western Blot View PTPRS (PTP- sigma), Active
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
CDC25A, Active C04-20G Phosphatase Assay, Western Blot View CDC25A, Active
CDC25B, Active C04-20BG Phosphatase Assay, Western Blot View CDC25B, Active
CDC25C, Active C04-20CG Phosphatase Assay, Western Blot View CDC25C, Active
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
DUSP22 (MKPX), Active D22-20G Phosphatase Assay, Western Blot View DUSP22 (MKPX), Active
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
PP1A, Active P13-20G Phosphatase Assay, Western Blot View PP1A, Active
PP1B, Active P14-20G Phosphatase Assay, Western Blot View PP1B, Active
PP2Aalpha, Active P16-20G Phosphatase Assay, Western Blot View PP2Aalpha, Active
PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
PTEN, Active P23-20G Phosphatase Assay, Western Blot View PTEN, Active
PTPN1 (PTP1B), Active P28-20G Phosphatase Assay, Western Blot View PTPN1 (PTP1B), Active
PTPN11 (SHP2), Active P38-21G Phosphatase Assay, Western Blot View PTPN11 (SHP2), Active
PTPN12 (PTP-PEST), Active P39-21G Phosphatase Assay, Western Blot View PTPN12 (PTP-PEST), Active
PTPN13 (FAP-1), Active P40-21G Phosphatase Assay, Western Blot View PTPN13 (FAP-1), Active
PTPN2 (TC-PTP), Active P29-20G Phosphatase Assay, Western Blot View PTPN2 (TC-PTP), Active
PTPN6 (SHP1), Active P33-20G Phosphatase Assay, Western Blot View PTPN6 (SHP1), Active
PTPN7 (LC-PTP), Active P34-20G Phosphatase Assay, Western Blot View PTPN7 (LC-PTP), Active
PTPRA (LRP), Active P48-21G Phosphatase Assay, Western Blot View PTPRA (LRP), Active
PTPRC (CD45), Active P50-21H Phosphatase Assay, Western Blot View PTPRC (CD45), Active
PTPRC (CD45), Active P50-21BG Phosphatases Assay, Western Blot View PTPRC (CD45), Active
PTPRE, Active P52-21G Phosphatase Assay, Western Blot View PTPRE, Active
PTPRF (LAR), Active P53-21G Phosphatase Assay, Western Blot View PTPRF (LAR), Active
PTPRS (PTP- sigma), Active P64-21G Phosphatase Assay, Western Blot View PTPRS (PTP- sigma), Active
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes
Active Phosphatases Product Listing Found: Total 23 Products Matching Active Phosphatases
Product Name Catalog Number Application Pack Sizes


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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