: Recombinant protein stored in 1 X PBS, 10% glycerol.
Storage, Stability, and Shipping
: Stored at desiccated below -20o
C. It is stable at 4o
C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
: Cell Assay
: Less than 0.1 ng/µg (IEU/µg) of IP-10.
: ~13.2 kDa
: C7; IFI10; INP10; crg-2; mob-1; SCYB10; gIP-10; CXCL10
: IP10 or interferon gamma inducible protein 10 is a member of the CXC chemokine family that plays a role in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. IP10 participate in the regulation of angiogenesis during inflammation and tumorigenesis (1). IP10 plays a role in the generation and delivery of an effector T-cell response (2).
1. Angiolillo, A. L. et.al: Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J. Exp. Med. 182: 155-162, 1995.
2. Dufour, J. H. et.al: IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J. Immun. 168: 3195-3204, 2002.
||Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
The IP-10 product can be utilized in the following research areas, but not limited to:
AKT/PKB Pathway, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, NfkB Pathway, p38 Pathway, PKA/PKC Pathway