AKT/PKB Pathway


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AKT/PKB Pathway

The AKT (or PKB) signaling pathway has been the subject of intense investigation for over a decade as it regulates a multitude of cellular processes including cell proliferation and survival, cell size and response to nutrient availability, glucose metabolism, tissue invasion and angiogenesis. AKT functions as a cardinal nodal point in this pathway for transducing extracellular (growth factor and insulin) and intracellular (receptor tyrosine kinases, Ras and Src) signals. The AKT pathway is ubiquitous in nature and operates in cells to regulate fundamental cellular processes.


AKT, a serine/threonine kinase, is a central component in the AKT pathway and exists as three isoforms in mammals (AKT1, AKT2 and AKT3). AKT is downstream of a key lipid kinase target, PI3K, which is responsible for the generation of the PIP3 phospholipid second messenger. Activation of AKT requires binding to PIP3 via the pleckstrin homology domain and activation loop phosphorylation on AKT at Thr308 by PDK1 and phosphorylation within the carboxy-terminus at Ser473 by PDK2 (1).


Alterations in the AKT pathway, and specifically AKT itself, have been detected in a number of human malignancies (2). Ectopic expression of AKT, especially constitutively activated AKT, is sufficient to induce oncogenic transformation of cells and tumor formation in transgenic mice as well as chemoresistance. Many tumors and tumor cells display elevated AKT protein expression and activity, and many of the proteins which regulate AKT itself (i.e., PI3K, PTEN, Ras, Src and tyrosine kinases) are also often mutated in cancer. Blockage of AKT signaling results in apoptosis and growth inhibition of tumor cells with elevated AKT. The observed dependence of certain tumors on AKT signaling for survival and growth has wide implications for cancer therapy, offering the potential for preferential tumor cell killing. In the last several years, through combinatorial chemistry, high-throughput and virtual screening, and traditional medicinal chemistry efforts, a number of inhibitors of the AKT pathway have been identified that are being further pursued for clinical utility (3).


REFERENCES
1. Vanhaesebroeck, B., et al.: The PI3K-PDK1 connection: more than just a road to PKB. Biochem J. 2000 Mar 15;346 Pt 3:561-76.
2. Altomare, D. A., et al.: Perturbations of the AKT signaling pathway in human cancer. Oncogene. 2005 Nov 14;24(50):7455-64.
3. Kumar, C. C., et al.: AKT crystal structure and AKT-specific inhibitors. Oncogene. 2005 Nov 14;24(50):7493-501.


AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein New Research Category Y71-30BH Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30G Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein New Research Category Y71-30H Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30N Western Blot View 14-3-3 alpha/beta Protein
siRNA Sets 14-3-3 alpha/beta siRNA Set I Y71-911 View 14-3-3 alpha/beta siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein New Research Category Y75-30BH Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein New Research Category Y75-30H Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30N Western Blot View 14-3-3 epsilon Protein
siRNA Sets 14-3-3 epsilon siRNA Set I Y75-911 View 14-3-3 epsilon siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30BH Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30H Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30N Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein (C-term GST) New Research Category Y76-30CG Western Blot View 14-3-3 eta Protein (C-term GST)
Cell Stress & Chaperone Proteins 14-3-3 eta Protein (N-term GST) New Research Category Y76-30G Western Blot View 14-3-3 eta Protein (N-term GST)
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30BH Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30H Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30N Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein (C-term GST) New Research Category Y77-30CG Western Blot View 14-3-3 gamma Protein (C-term GST)
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein (N-term GST) New Research Category Y77-30G Western Blot View 14-3-3 gamma Protein (N-term GST)
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30G Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein New Research Category Y86-30H Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30N Western Blot View 14-3-3 sigma Protein
siRNA Sets 14-3-3 sigma siRNA Set I Y86-911 View 14-3-3 sigma siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 theta Protein New Research Category Y84-30BH Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein New Research Category Y84-30H Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
siRNA Sets 14-3-3 theta siRNA Set I Y84-911 View 14-3-3 theta siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein New Research Category Y92-30BH Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30G Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein New Research Category Y92-30H Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30N Western Blot View 14-3-3 zeta Protein
siRNA Sets 14-3-3 zeta siRNA Set I Y92-911 View 14-3-3 zeta siRNA Set I
Cellular Proteins 4EBP1 Protein E35-54BH Kinase Assay, Western Blot View 4EBP1 Protein
Cellular Proteins 4EBP1 Protein E35-54G Kinase Assay, Western Blot View 4EBP1 Protein
Cellular Proteins 4EBP1 Protein E35-54H Western Blot View 4EBP1 Protein
siRNA Sets 4EBP1 siRNA Set I E35-911 View 4EBP1 siRNA Set I
Kinase Inhibitors 6BIO G08-900 View 6BIO
Kinase Activators 8-pCPT-2-O-Me-cAMP-AM R46-905 View 8-pCPT-2-O-Me-cAMP-AM
Kinase Inhibitors A83-01 A09-900 View A83-01
Assay Reagents Acetyltransferase Assay Buffer A01-09 Acetyltransferase Assay View Acetyltransferase Assay Buffer
siRNA Sets AFX siRNA Set I A42-911 View AFX siRNA Set I
Kinase Inhibitors AG-1296 P12-900 View AG-1296
Kinase Inhibitors AG-1478 E10-900B View AG-1478
Kinase Inhibitors AG-879 N28-909B View AG-879
Peptide Substrates AKT (PKB) Substrate A05-58 Kinase Assay View AKT (PKB) Substrate
Peptide Substrates AKT (SGK) Substrate A08-58 Kinase Assay View AKT (SGK) Substrate
Active Kinase Mutants AKT1 Mutant (E17K), Active A16-12G Kinase Assay View AKT1 Mutant (E17K), Active
Active Kinases AKT1, Active A16-10G Kinase Assay, Western Blot View AKT1, Active
Unactive Kinases AKT1, Unactive A16-14G Kinase Assay, Western Blot View AKT1, Unactive
siRNA Sets AKT1/PKB alpha siRNA Set I A16-911 View AKT1/PKB alpha siRNA Set I
Active Kinase Mutants AKT2 Mutant (E17K), Active A17-12G Kinase Assay View AKT2 Mutant (E17K), Active
Active Kinase Mutants AKT2 Mutant (R274H), Active A17-12BG Kinase Assay View AKT2 Mutant (R274H), Active
Active Kinases AKT2, Active A17-10G Kinase Assay, Western Blot View AKT2, Active
Active Kinases AKT2, Active A17-10H Kinase Assay, Western Blot View AKT2, Active
Unactive Kinases AKT2, Unactive A17-14G Kinase Assay, Western Blot View AKT2, Unactive
Unactive Kinases AKT2, Unactive A17-15H Kinase Assay, Western Blot View AKT2, Unactive
siRNA Sets AKT2/PKB beta siRNA Set I A17-911 View AKT2/PKB beta siRNA Set I
Active Kinase Mutants AKT3 Mutant (E17K), Active A18-12G Kinase Assay View AKT3 Mutant (E17K), Active
Active Kinase Mutants AKT3 Mutant (G171R), Active A18-12BG Kinase Assay View AKT3 Mutant (G171R), Active
siRNA Sets AKT3 siRNA Set I A18-911 View AKT3 siRNA Set I
Active Kinases AKT3, Active A18-10G Kinase Assay, Western Blot View AKT3, Active
Unactive Kinases AKT3, Unactive A18-14G Kinase Assay, Western Blot View AKT3, Unactive
Active Kinase Mutants ALK Mutant (C1156Y), Active A19-12DG Kinase Assay View ALK Mutant (C1156Y), Active
Active Kinase Mutants ALK Mutant (F1174L), Active A19-12EG Kinase Assay View ALK Mutant (F1174L), Active
Active Kinase Mutants ALK Mutant (F1174S), Active A19-12FG Kinase Assay View ALK Mutant (F1174S), Active
Active Kinase Mutants ALK Mutant (G1202R), Active A19-12HG Kinase Assay View ALK Mutant (G1202R), Active
Active Kinase Mutants ALK Mutant (G1269A), Active A19-12JG Kinase Assay View ALK Mutant (G1269A), Active
Active Kinase Mutants ALK Mutant (G1269S), Active A19-12KG Kinase Assay View ALK Mutant (G1269S), Active
Active Kinase Mutants ALK Mutant (L1152R), Active A19-12CG Kinase Assay View ALK Mutant (L1152R), Active
Active Kinase Mutants ALK Mutant (L1196M), Active A19-12GG Kinase Assay View ALK Mutant (L1196M), Active
Active Kinase Mutants ALK Mutant (R1275Q), Active A19-12LG Kinase Assay View ALK Mutant (R1275Q), Active
Active Kinase Mutants ALK Mutant (S1206R), Active A19-12IG Kinase Assay View ALK Mutant (S1206R), Active
Active Kinase Mutants ALK Mutant (T1151M), Active A19-12BG Kinase Assay View ALK Mutant (T1151M), Active
Active Kinase Mutants ALK Mutant (T1151_L1152insT), Active A19-12G Kinase Assay View ALK Mutant (T1151_L1152insT), Active
Active Kinases ALK, Active A19-11G Kinase Assay, Western Blot View ALK, Active
siRNA Sets ALK1 siRNA Set I A09-911 View ALK1 siRNA Set I
Active Kinases ALK1, Active A09-11G Kinase Assay, Western Blot View ALK1, Active
Active Kinase Mutants ALK2 Mutant (PF197_198L), Active A06-12FG Kinase Assay View ALK2 Mutant (PF197_198L), Active
Active Kinase Mutants ALK2 Mutant (Q207D), Active A06-13CG Kinase Assay View ALK2 Mutant (Q207D), Active
Active Kinase Mutants ALK2 Mutant (Q207E), Active A06-13DG Kinase Assay View ALK2 Mutant (Q207E), Active
Active Kinase Mutants ALK2 Mutant (R206H), Active A06-12BG Kinase Assay View ALK2 Mutant (R206H), Active
siRNA Sets ALK2 siRNA Set I A06-911 View ALK2 siRNA Set I
Active Kinases ALK2, Active A06-11G Kinase Assay, Western Blot View ALK2, Active
siRNA Sets ALK3 (BMPR1A) siRNA Set I B04-911 View ALK3 (BMPR1A) siRNA Set I
Active Kinases ALK3 (BMPR1A), Active B04-11G Kinase Assay, Western Blot View ALK3 (BMPR1A), Active
Active Kinase Mutants ALK3 Mutant (Q233D), Active B04-12BG Kinase Assay View ALK3 Mutant (Q233D), Active
Active Kinase Mutants ALK3 Mutant (R486Q), Active B04-12CG Kinase Assay View ALK3 Mutant (R486Q), Active
Active Kinases ALK4, Active A07-11G Kinase Assay, Western Blot View ALK4, Active
siRNA Sets ALK6 (BMPR1B) siRNA Set I B05-911 View ALK6 (BMPR1B) siRNA Set I
Active Kinases ALK6 (BMPR1B), Active B05-11G Kinase Assay, Western Blot View ALK6 (BMPR1B), Active
Kinase Protein ALK7 Protein A08-35G Western Blot View ALK7 Protein
siRNA Sets ALK7 siRNA Set I A08-911 View ALK7 siRNA Set I
Kinase Inhibitors Alsterpaullone G09-901C View Alsterpaullone
Primary Antibodies Anti-4EBP1 E35-563R WB, ELISA, ICC View Anti-4EBP1
Primary Antibodies Anti-AFX A42-63R WB View Anti-AFX
Primary Antibodies Anti-AKT1 A16-60M WB View Anti-AKT1
Primary Antibodies Anti-AKT1 A16-63CR WB, ELISA, IF, IHC View Anti-AKT1
Primary Antibodies Anti-AKT2/3 A17-63BR WB View Anti-AKT2/3
Isoform Specific Antibodies Anti-AKT3 A18-63R WB View Anti-AKT3
Primary Antibodies Anti-ALK2 A06-63R WB, ELISA View Anti-ALK2
Primary Antibodies Anti-ALK4 A07-63R WB, ELISA View Anti-ALK4
Primary Antibodies Anti-ALK7 A08-63R WB, ELISA View Anti-ALK7
Primary Antibodies Anti-BAG1 B05-363BR WB, ELISA, IF, IHC View Anti-BAG1
Primary Antibodies Anti-BAG1 B05-363R WB, ELISA View Anti-BAG1
Primary Antibodies Anti-BAX B14-363R WB, ELISA, ICC, IF View Anti-BAX
Primary Antibodies Anti-BMPR2 B06-63R WB, ELISA, IHC View Anti-BMPR2
Primary Antibodies Anti-DYRK1A D09-63R WB, ELISA, IF View Anti-DYRK1A
Primary Antibodies Anti-DYRK2 D10-63R WB, ELISA, ICC, IF View Anti-DYRK2
Primary Antibodies Anti-EGFR E10-63BR WB View Anti-EGFR
Primary Antibodies Anti-EGFR E10-63R WB View Anti-EGFR
Primary Antibodies Anti-FLT3 F12-63R WB, ELISA, IF View Anti-FLT3
Isoform Specific Antibodies Anti-GSK3 alpha G08-63R WB View Anti-GSK3 alpha
Primary Antibodies Anti-GSK3 alpha/beta G09-63R WB View Anti-GSK3 alpha/beta
Isoform Specific Antibodies Anti-GSK3 beta G09-60M WB View Anti-GSK3 beta
Primary Antibodies Anti-HER2 E27-63R WB, ELISA, IF, IHC View Anti-HER2
Isoform Specific Antibodies Anti-HSP90 beta H36-63R WB View Anti-HSP90 beta
Primary Antibodies Anti-IKK alpha C51-63BR WB, ELISA, ICC, IF View Anti-IKK alpha
Primary Antibodies Anti-IKK alpha C51-63CR WB, ELISA, ICC View Anti-IKK alpha
Primary Antibodies Anti-IKK alpha C51-63R WB, ELISA, ICC, IF View Anti-IKK alpha
Primary Antibodies Anti-IKK beta I03-63R WB, ELISA, ICC, IF View Anti-IKK beta
Primary Antibodies Anti-IKK epsilon I04-63R WB, ELISA, IHC View Anti-IKK epsilon
Primary Antibodies Anti-IKK gamma I25-63R WB, ELISA, ICC View Anti-IKK gamma
Primary Antibodies Anti-IRS1 I40-363R WB, ELISA, ICC, IF View Anti-IRS1
Primary Antibodies Anti-mTOR F17-63BR WB, ELISA, ICC View Anti-mTOR
Primary Antibodies Anti-mTOR F17-63R WB View Anti-mTOR
Primary Antibodies Anti-NF-kB p105 N12-63R WB View Anti-NF-kB p105
Primary Antibodies Anti-p70S6K R21-63BR WB View Anti-p70S6K
Primary Antibodies Anti-p70S6K R21-63R WB View Anti-p70S6K
Primary Antibodies Anti-PDGFB P842-63R WB, ELISA View Anti-PDGFB
Primary Antibodies Anti-PHLPP1 P71-263R WB, ELISA View Anti-PHLPP1
Primary Antibodies Anti-PHLPP2 P72-263R WB, ELISA View Anti-PHLPP2
Phospho Specific Antibodies Anti-phospho-14-3-3 beta (Ser58) Y71-365R WB, IHC View Anti-phospho-14-3-3 beta (Ser58)
Phospho Specific Antibodies Anti-phospho-4EBP1 (Thr45) E35-365R WB, IHC View Anti-phospho-4EBP1 (Thr45)
Phospho Specific Antibodies Anti-phospho-AKT1/2/3 (Ser473) A16-65BR WB, IHC View Anti-phospho-AKT1/2/3 (Ser473)
Phospho Specific Antibodies Anti-phospho-AKT1/2/3 (Thr308) A16-65R WB, IHC View Anti-phospho-AKT1/2/3 (Thr308)
Phospho Specific Antibodies Anti-phospho-EGFR (Thr678) E10-65BR WB View Anti-phospho-EGFR (Thr678)
Phospho Specific Antibodies Anti-phospho-EGFR (Thr693) E10-65CR WB View Anti-phospho-EGFR (Thr693)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1092) E10-65DR WB, IHC View Anti-phospho-EGFR (Tyr1092)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1110) E10-65ER WB View Anti-phospho-EGFR (Tyr1110)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1197) E10-65FR WB, IHC View Anti-phospho-EGFR (Tyr1197)
Phospho Specific Antibodies Anti-phospho-GSK3 beta (Ser9) G09-652R WB View Anti-phospho-GSK3 beta (Ser9)
Phospho Specific Antibodies Anti-phospho-GSK3 beta (Ser9) G09-65R WB, IHC View Anti-phospho-GSK3 beta (Ser9)
Phospho Specific Antibodies Anti-phospho-HER2 (Tyr877) E27-65R WB, IHC View Anti-phospho-HER2 (Tyr877)
Phospho Specific Antibodies Anti-phospho-IRS1 (Ser312) I40-365R WB View Anti-phospho-IRS1 (Ser312)
Phospho Specific Antibodies Anti-phospho-IRS1 (Ser639) I40-365BR IHC View Anti-phospho-IRS1 (Ser639)
Phospho Specific Antibodies Anti-phospho-KDR (Tyr1214) K01-65BR IHC View Anti-phospho-KDR (Tyr1214)
Phospho Specific Antibodies Anti-phospho-KDR (Tyr951) K01-65R WB, IHC View Anti-phospho-KDR (Tyr951)
Phospho Specific Antibodies Anti-phospho-mTOR (Ser2448) F17-65R IHC View Anti-phospho-mTOR (Ser2448)
Phospho Specific Antibodies Anti-phospho-PDK1 (Ser241) P14-65R WB, IHC View Anti-phospho-PDK1 (Ser241)
Modification Antibodies Anti-Phosphoserine (Anti-pS) S95-65R WB, ELISA, IHC, IP View Anti-Phosphoserine (Anti-pS)
Modification Antibodies Anti-Phosphoserine (Anti-pS), Biotin Conjugated S95-65BR WB, ELISA View Anti-Phosphoserine (Anti-pS), Biotin Conjugated
Modification Antibodies Anti-Phosphothreonine (Anti-pT) T95-65R WB, ELISA, IHC, IP View Anti-Phosphothreonine (Anti-pT)
Modification Antibodies Anti-Phosphothreonine (Anti-pT), Biotin Conjugated T95-65BR WB, ELISA View Anti-Phosphothreonine (Anti-pT), Biotin Conjugated
Modification Antibodies Anti-Phosphotyrosine (Anti-pY) T96-65R WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY)
Modification Antibodies Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated T96-65BR WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated
Primary Antibodies Anti-PTEN P23-263BR WB, ELISA, IF View Anti-PTEN
Primary Antibodies Anti-PTEN P23-263R WB, ELISA View Anti-PTEN
Primary Antibodies Anti-Rel A R29-63BR WB View Anti-Rel A
Primary Antibodies Anti-Rel A R29-63R WB View Anti-Rel A
Primary Antibodies Anti-SGK1 S06-63R WB, ELISA, IF, IHC View Anti-SGK1
Isoform Specific Antibodies Anti-SMAD2 S11-63R WB View Anti-SMAD2
Primary Antibodies Anti-TAB1 T01-363R WB, ELISA, ICC, IF View Anti-TAB1
Primary Antibodies Anti-TAK1 M15-63R WB, ELISA, IF, IHC View Anti-TAK1
Primary Antibodies Anti-Trail T880-63R WB, ELISA, IHC View Anti-Trail
Kinase Inhibitors Apigenin K10-900C View Apigenin
Kinase Inhibitors AR-A014418 G09-901 View AR-A014418
Kinase Inhibitors AS-041164 P29-901 View AS-041164
Apoptosis Proteins BAG1 Protein B05-31G Western Blot View BAG1 Protein
siRNA Sets BAG1 siRNA Set I B05-911B View BAG1 siRNA Set I
Apoptosis Proteins BAX Protein B14-30G Western Blot View BAX Protein
siRNA Sets BAX siRNA Set I B14-911 View BAX siRNA Set I
Kinase Inhibitors BAY 11-7082 C51-900 View BAY 11-7082
Growth Factors BMP-2 B851-40N Cell Assay View BMP-2
siRNA Sets BMP-2 siRNA Set I B851-911 View BMP-2 siRNA Set I
Growth Factors BMP-4 B853-40N Cell Assay View BMP-4
siRNA Sets BMP-4 siRNA Set I B853-911 View BMP-4 siRNA Set I
Kinase Protein BMP2K Protein B03-11G Western Blot View BMP2K Protein
siRNA Sets BMP2K siRNA Set I B03-911B View BMP2K siRNA Set I
siRNA Sets BMPR2 siRNA Set I B06-911 View BMPR2 siRNA Set I
Active Kinases BMPR2, Active B06-11H Kinase Assay, Western Blot View BMPR2, Active
Kinase Protein CDK12 (CRKRS) Protein C62-35G Kinase Assay, Western Blot View CDK12 (CRKRS) Protein
Kinase Inhibitors CHIR-99021 G09-901B View CHIR-99021
Peptide Substrates Crosstide C51-58 Kinase Assay View Crosstide
Kinase Inhibitors Deguelin A16-900B View Deguelin
Kinase Inhibitors DMPQ 2 HCl P13-901 View DMPQ 2 HCl
Dihydropyrimidinase DPYSL2 Protein D470-30BG Western Blot View DPYSL2 Protein
siRNA Sets DYRK1A siRNA Set I D09-911 View DYRK1A siRNA Set I
Active Kinases DYRK1A, Active D09-10G Kinase Assay, Western Blot View DYRK1A, Active
Active Kinases DYRK1B, Active D09-10BG Kinase Assay, Western Blot View DYRK1B, Active
siRNA Sets DYRK2 siRNA Set I D10-911 View DYRK2 siRNA Set I
Active Kinases DYRK2, Active D10-10G Kinase Assay, Western Blot View DYRK2, Active
siRNA Sets DYRK3 siRNA Set I D11-911 View DYRK3 siRNA Set I
Active Kinases DYRK3, Active D11-11G Kinase Assay, Western Blot View DYRK3, Active
Active Kinases DYRK4, Active D12-10G Kinase Assay, Western Blot View DYRK4, Active
Peptide Substrates DYRKtide D96-58 Kinase Assay View DYRKtide
siRNA Sets EEF2K siRNA Set I E01-911 View EEF2K siRNA Set I
Active Kinases EEF2K, Active E01-10G Kinase Assay, Western Blot View EEF2K, Active
EF2tide E01-58 View EF2tide
Peptide Substrates EF2tide E01-58 Kinase Assay View EF2tide
Active Kinase Mutants EGFR Mutant (A763_Y764insFHEA), Active E10-132BG Kinase Assay View EGFR Mutant (A763_Y764insFHEA), Active
Active Kinase Mutants EGFR Mutant (A763_Y764insFHEA), Active E10-13BG Kinase Assay View EGFR Mutant (A763_Y764insFHEA), Active
Kinase Mutant Proteins EGFR Mutant (A767_S768insTLA) Protein E10-13CG Kinase Assay View EGFR Mutant (A767_S768insTLA) Protein
Active Kinase Mutants EGFR Mutant (C775S T790M L858R), Active New Research Category E10-122D2G Kinase Assay View EGFR Mutant (C775S T790M L858R), Active
Active Kinase Mutants EGFR Mutant (C797A), Active E10-12RG Kinase Assay View EGFR Mutant (C797A), Active
Active Kinase Mutants EGFR Mutant (C797S L858R), Active E10-122ZG Kinase Assay View EGFR Mutant (C797S L858R), Active
Active Kinase Mutants EGFR Mutant (C797S), Active E10-122SG Kinase Assay View EGFR Mutant (C797S), Active
Active Kinase Mutants EGFR Mutant (C797S), Active E10-12SG Kinase Assay View EGFR Mutant (C797S), Active
Active Kinase Mutants EGFR Mutant (d746), Active E10-12IG Kinase Assay View EGFR Mutant (d746), Active
Active Kinase Mutants EGFR Mutant (d746-750 C775S T790M L858R), Active New Research Category E10-122E2G Kinase Assay View EGFR Mutant (d746-750 C775S T790M L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797A), Active E10-122C2G Kinase Assay View EGFR Mutant (d746-750 C797A), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797S), Active E10-122TG Kinase Assay View EGFR Mutant (d746-750 C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797S), Active E10-12TG Kinase Assay View EGFR Mutant (d746-750 C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S L858R), Active E10-122YG Kinase Assay View EGFR Mutant (d746-750 T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S), Active E10-122UG Kinase Assay View EGFR Mutant (d746-750 T790M C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S), Active E10-12UG Kinase Assay View EGFR Mutant (d746-750 T790M C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M L858R), Active E10-122XG Kinase Assay View EGFR Mutant (d746-750 T790M L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M L978I), Active E10-122WG Kinase Assay View EGFR Mutant (d746-750 T790M L978I), Active
Kinase Mutant Proteins EGFR Mutant (d746-750 T790M) Protein E10-12KG Kinase Assay View EGFR Mutant (d746-750 T790M) Protein
Active Kinase Mutants EGFR Mutant (d746-750 T790M), Active E10-122KG Kinase Assay View EGFR Mutant (d746-750 T790M), Active
Active Kinase Mutants EGFR Mutant (d746-750), Active E10-122JG Kinase Assay View EGFR Mutant (d746-750), Active
Active Kinase Mutants EGFR Mutant (d746-750), Active E10-12JG Kinase Assay View EGFR Mutant (d746-750), Active
Active Kinase Mutants EGFR Mutant (d747-749 A750P), Active E10-12MG Kinase Assay View EGFR Mutant (d747-749 A750P), Active
Active Kinase Mutants EGFR Mutant (d747-749), Active E10-12LG Kinase Assay View EGFR Mutant (d747-749), Active
Active Kinase Mutants EGFR Mutant (d747-752 P753S), Active E10-12NG Kinase Assay View EGFR Mutant (d747-752 P753S), Active
Active Kinase Mutants EGFR Mutant (d752-759), Active E10-12OG Kinase Assay View EGFR Mutant (d752-759), Active
Active Kinase Mutants EGFR Mutant (D761Y), Active E10-12QG Kinase Assay View EGFR Mutant (D761Y), Active
Active Kinase Mutants EGFR Mutant (D770GY), Active E10-13KG Kinase Assay View EGFR Mutant (D770GY), Active
Active Kinase Mutants EGFR Mutant (D770_N771insGF) Protein E10-13IG Kinase Assay View EGFR Mutant (D770_N771insGF) Protein
Active Kinase Mutants EGFR Mutant (D770_N771insNPG), Active E10-132GG Kinase Assay View EGFR Mutant (D770_N771insNPG), Active
Active Kinase Mutants EGFR Mutant (D770_N771insNPG), Active E10-13GG Kinase Assay View EGFR Mutant (D770_N771insNPG), Active
Active Kinase Mutants EGFR Mutant (G719C), Active E10-12FG Kinase Assay View EGFR Mutant (G719C), Active
Active Kinase Mutants EGFR Mutant (G719D), Active E10-12GG Kinase Assay View EGFR Mutant (G719D), Active
Active Kinase Mutants EGFR Mutant (G719S), Active E10-12HG Kinase Assay View EGFR Mutant (G719S), Active
Active Kinase Mutants EGFR Mutant (H773_V774insAH) Protein E10-13PG Kinase Assay View EGFR Mutant (H773_V774insAH) Protein
Active Kinase Mutants EGFR Mutant (H773_V774insH) Protein E10-13RG Kinase Assay View EGFR Mutant (H773_V774insH) Protein
Kinase Mutant Proteins EGFR Mutant (H773_V774insNPH) Protein E10-13OG Kinase Assay View EGFR Mutant (H773_V774insNPH) Protein
Kinase Mutant Proteins EGFR Mutant (H773_V774insPH) Protein E10-13QG Kinase Assay View EGFR Mutant (H773_V774insPH) Protein
Active Kinase Mutants EGFR Mutant (L747S), Active E10-12PG Kinase Assay View EGFR Mutant (L747S), Active
Active Kinase Mutants EGFR Mutant (L858R), Active E10-122BG Kinase Assay View EGFR Mutant (L858R), Active
Active Kinase Mutants EGFR Mutant (L858R), Active E10-12BG Kinase Assay View EGFR Mutant (L858R), Active
Active Kinase Mutants EGFR Mutant (L861Q), Active E10-12CG Kinase Assay View EGFR Mutant (L861Q), Active
Active Kinase Mutants EGFR Mutant (P772_H773insNPH), Active E10-13MG Kinase Assay View EGFR Mutant (P772_H773insNPH), Active
Active Kinase Mutants EGFR Mutant (T790M C797S L858R), Active E10-122VG Kinase Assay View EGFR Mutant (T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (T790M C797S L858R), Active E10-12VG Kinase Assay View EGFR Mutant (T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (T790M C797S), Active E10-122B2G Kinase Assay View EGFR Mutant (T790M C797S), Active
Active Kinase Mutants EGFR Mutant (T790M L858R), Active E10-122DG Kinase Assay View EGFR Mutant (T790M L858R), Active
Active Kinase Mutants EGFR Mutant (T790M L858R), Active E10-12DG Kinase Assay View EGFR Mutant (T790M L858R), Active
Active Kinase Mutants EGFR Mutant (T790M), Active E10-122EG Kinase Assay View EGFR Mutant (T790M), Active
Active Kinase Mutants EGFR Mutant (T790M), Active E10-12EG Kinase Assay View EGFR Mutant (T790M), Active
Kinase Mutant Proteins EGFR Mutant (V769_D770insASV) Protein E10-13DG Kinase Assay View EGFR Mutant (V769_D770insASV) Protein
Kinase Mutant Proteins EGFR Mutant (V769_D770insGE) Protein E10-13EG Kinase Assay View EGFR Mutant (V769_D770insGE) Protein
siRNA Sets EGFR siRNA Set I E10-911 View EGFR siRNA Set I
Active Kinases EGFR, Active E10-112G Kinase Assay, Western Blot View EGFR, Active
Active Kinases EGFR, Active E10-11G Kinase Assay, Western Blot View EGFR, Active
Kinase Inhibitors Erlotinib HCl E10-900C View Erlotinib HCl
siRNA Sets FAK siRNA Set I P91-911 View FAK siRNA Set I
Active Kinases FAK, Active P91-10G Kinase Assay, Western Blot View FAK, Active
Active Kinases FAK, Active P91-11H Kinase Assay, Western Blot View FAK, Active
Active Kinases FGFR1 (FLT2), Active F04-11G Kinase Assay, Western Blot View FGFR1 (FLT2), Active
Active Kinase Mutants FGFR1 Mutant (V561M), Active F04-13G Kinase Assay View FGFR1 Mutant (V561M), Active
siRNA Sets FGFR1 siRNA Set I F04-911 View FGFR1 siRNA Set I
Active Kinase Mutants FGFR1OP-FGFR1 Mutant, Active F04-19BG Kinase Assay View FGFR1OP-FGFR1 Mutant, Active
Active Kinase Mutants FGFR2 Mutant (E565G), Active F05-12CG Kinase Assay View FGFR2 Mutant (E565G), Active
Active Kinase Mutants FGFR2 Mutant (K526E), Active F05-12BG Kinase Assay View FGFR2 Mutant (K526E), Active
Active Kinase Mutants FGFR2 Mutant (K641R), Active F05-12DG Kinase Assay View FGFR2 Mutant (K641R), Active
Active Kinase Mutants FGFR2 Mutant (K659N), Active F05-12EG Kinase Assay View FGFR2 Mutant (K659N), Active
Active Kinase Mutants FGFR2 Mutant (N549H), Active F05-12G Kinase Assay View FGFR2 Mutant (N549H), Active
Active Kinase Mutants FGFR2 Mutant (R612T), Active F05-12GG Kinase Assay, Western Blot View FGFR2 Mutant (R612T), Active
Active Kinase Mutants FGFR2 Mutant (V564F), Active F05-12FG Kinase Assay, Western Blot View FGFR2 Mutant (V564F), Active
siRNA Sets FGFR2 siRNA Set I F05-911 View FGFR2 siRNA Set I
Active Kinases FGFR2, Active F05-11G Kinase Assay, Western Blot View FGFR2, Active
Active Kinase Mutants FGFR3 Mutant (G697C), Active F06-12FG Kinase Assay View FGFR3 Mutant (G697C), Active
Active Kinase Mutants FGFR3 Mutant (K650E), Active F06-12CG Kinase Assay View FGFR3 Mutant (K650E), Active
Active Kinase Mutants FGFR3 Mutant (K650M), Active F06-12DG Kinase Assay View FGFR3 Mutant (K650M), Active
Active Kinase Mutants FGFR3 Mutant (K650Q), Active F06-12EG Kinase Assay View FGFR3 Mutant (K650Q), Active
Active Kinase Mutants FGFR3 Mutant (V555M), Active F06-12GG Kinase Assay View FGFR3 Mutant (V555M), Active
siRNA Sets FGFR3 siRNA Set I F06-911 View FGFR3 siRNA Set I
Active Kinases FGFR3, Active F06-11G Kinase Assay, Western Blot View FGFR3, Active
Active Kinase Mutants FGFR4 Mutant (N535K), Active F07-12G Kinase Assay View FGFR4 Mutant (N535K), Active
Active Kinase Mutants FGFR4 Mutant (V550E), Active F07-12BG Kinase Assay View FGFR4 Mutant (V550E), Active
Active Kinase Mutants FGFR4 Mutant (V550L), Active F07-12CG Kinase Assay View FGFR4 Mutant (V550L), Active
Active Kinase Mutants FGFR4 Mutant (V550M), Active F07-12DG Kinase Assay View FGFR4 Mutant (V550M), Active
siRNA Sets FGFR4 siRNA Set I F07-911 View FGFR4 siRNA Set I
Active Kinases FGFR4, Active F07-11G Kinase Assay, Western Blot View FGFR4, Active
Active Kinase Mutants FIP1L1-PDGFR alpha Mutant, Active P12-19BG Kinase Assay View FIP1L1-PDGFR alpha Mutant, Active
Cellular Proteins FKBP1A Protein F37-30G Western Blot View FKBP1A Protein
siRNA Sets FKBP1A siRNA Set I F37-911 View FKBP1A siRNA Set I
siRNA Sets FLT1 siRNA Set I F11-911 View FLT1 siRNA Set I
Active Kinases FLT1, Active F11-11G Kinase Assay, Western Blot View FLT1, Active
Active Kinase Mutants FLT3 Mutant (D835Y), Active F12-12BG Kinase Assay View FLT3 Mutant (D835Y), Active
Active Kinase Mutants FLT3 Mutant (F594_R595insR), Active F12-12EG Kinase Assay View FLT3 Mutant (F594_R595insR), Active
Active Kinase Mutants FLT3 Mutant (F594_R595insREY), Active F12-12FG Kinase Assay View FLT3 Mutant (F594_R595insREY), Active
Active Kinase Mutants FLT3 Mutant (N676K), Active F12-12IG Kinase Assay View FLT3 Mutant (N676K), Active
Active Kinase Mutants FLT3 Mutant (R595_E596insEY), Active F12-12GG Kinase Assay View FLT3 Mutant (R595_E596insEY), Active
Active Kinase Mutants FLT3 Mutant (Y591-V592insVDFREYEYD), Active F12-12HG Kinase Assay View FLT3 Mutant (Y591-V592insVDFREYEYD), Active
siRNA Sets FLT3 siRNA Set I F12-911 View FLT3 siRNA Set I
Active Kinases FLT3, Active F12-11G Kinase Assay, Western Blot View FLT3, Active
Active Kinase Mutants FLT3-ITD-NPOS Mutant, Active F12-12DG Kinase Assay View FLT3-ITD-NPOS Mutant, Active
Active Kinase Mutants FLT3-ITD-W51 Mutant, Active F12-12CG Kinase Assay View FLT3-ITD-W51 Mutant, Active
siRNA Sets FLT4 siRNA Set I F13-911 View FLT4 siRNA Set I
Active Kinases FLT4, Active F13-11G Kinase Assay, Western Blot View FLT4, Active
Cellular Proteins FRS3 Protein F80-30G Kinase Assay, Western Blot View FRS3 Protein
siRNA Sets FRS3 siRNA Set I F80-911 View FRS3 siRNA Set I
Kinase Inhibitors Gefitinib E10-900 View Gefitinib
Active GTPases/ATPases GNAI1, Active New Research Category G121-310G Enzyme Assay View GNAI1, Active
Active GTPases/ATPases GNAI2, Active New Research Category G122-310G Enzyme Assay View GNAI2, Active
Active GTPases/ATPases GNAI3, Active New Research Category G123-310G Enzyme Assay View GNAI3, Active
Peptide Substrates GS Peptide G60-58 Kinase Assay View GS Peptide
siRNA Sets GSK3 alpha siRNA Set I G08-911 View GSK3 alpha siRNA Set I
Active Kinases GSK3 alpha, Active G08-10G Kinase Assay, Western Blot View GSK3 alpha, Active
siRNA Sets GSK3 beta siRNA Set I G09-911 View GSK3 beta siRNA Set I
Active Kinases GSK3 beta, Active G09-10G Kinase Assay, Western Blot View GSK3 beta, Active
Active Kinases GSK3 beta, Active G09-10H Kinase Assay, Western Blot View GSK3 beta, Active
Unactive Kinases GSK3 beta, Unactive G09-14G Kinase Assay, Western Blot View GSK3 beta, Unactive
Peptide Substrates GSK3 Substrate G50-58 Kinase Assay View GSK3 Substrate
Kinase Inhibitors GW-441756 N28-909 View GW-441756
Kinase Protein H11 (HSP22) Protein H09-34G Western Blot View H11 (HSP22) Protein
Active Kinase Mutants HER2 Mutant (A775_G776insYVMA), Active E27-13BG Kinase Assay View HER2 Mutant (A775_G776insYVMA), Active
Active Kinase Mutants HER2 Mutant (d755-759), Active E27-12BG Kinase Assay View HER2 Mutant (d755-759), Active
Active Kinase Mutants HER2 Mutant (D769H), Active E27-12GG Kinase Assay View HER2 Mutant (D769H), Active
Active Kinase Mutants HER2 Mutant (D769Y), Active E27-12HG Kinase Assay View HER2 Mutant (D769Y), Active
Kinase Mutant Proteins HER2 Mutant (E719G) Protein E27-12CG Kinase Assay View HER2 Mutant (E719G) Protein
Kinase Mutant Proteins HER2 Mutant (E719K) Protein E27-12DG Kinase Assay View HER2 Mutant (E719K) Protein
Active Kinase Mutants HER2 Mutant (G776VC), Active E27-13EG Kinase Assay View HER2 Mutant (G776VC), Active
Active Kinase Mutants HER2 Mutant (I767M), Active E27-12NG Kinase Assay View HER2 Mutant (I767M), Active
Active Kinase Mutants HER2 Mutant (L755S), Active E27-12EG Kinase Assay View HER2 Mutant (L755S), Active
Active Kinase Mutants HER2 Mutant (L755W), Active E27-12FG Kinase Assay View HER2 Mutant (L755W), Active
Active Kinase Mutants HER2 Mutant (P780_Y781insGSP), Active E27-13DG Kinase Assay View HER2 Mutant (P780_Y781insGSP), Active
Active Kinase Mutants HER2 Mutant (R896C), Active E27-12KG Kinase Assay View HER2 Mutant (R896C), Active
Active Kinase Mutants HER2 Mutant (V777L), Active E27-12IG Kinase Assay View HER2 Mutant (V777L), Active
Active Kinase Mutants HER2 Mutant (V777_G778insCG), Active E27-13CG Kinase Assay View HER2 Mutant (V777_G778insCG), Active
Active Kinase Mutants HER2 Mutant (V842I), Active E27-12JG Kinase Assay View HER2 Mutant (V842I), Active
siRNA Sets HER2 siRNA Set I E27-911 View HER2 siRNA Set I
Peptide Substrates HER2 Substrate E27-58 Kinase Assay View HER2 Substrate
Active Kinases HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
siRNA Sets HER4 siRNA Set I E29-911 View HER4 siRNA Set I
Active Kinases HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Cell Stress & Chaperone Proteins HSP90 alpha Protein H36-50H Western Blot View HSP90 alpha Protein
Cell Stress & Chaperone Proteins HSP90 beta Protein H36-54H ATPase Assay, Western Blot View HSP90 beta Protein
siRNA Sets IGF1R siRNA Set I I02-911 View IGF1R siRNA Set I
Active Kinases IGF1R, Active I02-11H Kinase Assay, Western Blot View IGF1R, Active
Peptide Substrates IGF1Rtide I15-58 Kinase Assay View IGF1Rtide
Transcription Proteins IkBA Protein I20-30G Kinase Assay, Western Blot View IkBA Protein
Transcription Proteins IkBA Protein I20-31G Kinase Assay, Western Blot View IkBA Protein
siRNA Sets IkBalpha siRNA Set I I20-911 View IkBalpha siRNA Set I
Transcription Proteins IkBB Protein I21-30G Kinase Assay, Western Blot View IkBB Protein
siRNA Sets IkBbeta siRNA Set I I21-911 View IkBbeta siRNA Set I
siRNA Sets IKK alpha siRNA Set I C51-911 View IKK alpha siRNA Set I
Active Kinases IKK alpha, Active C51-10G Kinase Assay, Western Blot View IKK alpha, Active
siRNA Sets IKK beta siRNA Set I I03-911 View IKK beta siRNA Set I
Active Kinases IKK beta, Active I03-10BG Kinase Assay, Western Blot View IKK beta, Active
Active Kinases IKK beta, Active I03-18G Kinase Assay, Western Blot View IKK beta, Active
siRNA Sets IKK epsilon siRNA Set I I04-911 View IKK epsilon siRNA Set I
Active Kinases IKK epsilon, Active I04-10G Kinase Assay, Western Blot View IKK epsilon, Active
Cellular Proteins IKK gamma Protein I25-30G Western Blot View IKK gamma Protein
siRNA Sets IKKgamma siRNA Set I I25-911 View IKKgamma siRNA Set I
Peptide Substrates IKKtide I33-58 Kinase Assay View IKKtide
siRNA Sets IL-18 siRNA Set I I878-911 View IL-18 siRNA Set I
Growth Factors IL-2 I862-40N Cell Assay View IL-2
siRNA Sets IL-2 siRNA Set I I862-911 View IL-2 siRNA Set I
Growth Factors IL-8 (72AA) I868-40N Cell Assay View IL-8 (72AA)
siRNA Sets IL-8 (72AA) siRNA Set I I868-911 View IL-8 (72AA) siRNA Set I
siRNA Sets InsR siRNA Set I I08-911 View InsR siRNA Set I
Active Kinases InsR, Active I08-11G Kinase Assay, Western Blot View InsR, Active
Chemokines IP-10 I838-40N Cell Assay View IP-10
siRNA Sets IP-10 siRNA Set I I838-911 View IP-10 siRNA Set I
siRNA Sets IRR siRNA Set I I07-911 View IRR siRNA Set I
Active Kinases IRR, Active I07-11G Kinase Assay, Western Blot View IRR, Active
Cellular Proteins IRS1 (C-Term) Protein I40-31G Kinase Assay, Western Blot View IRS1 (C-Term) Protein
Cellular Proteins IRS1 (N-Term) Protein I40-35G Kinase Assay, Western Blot View IRS1 (N-Term) Protein
Peptide Substrates IRS1 (Y608) Peptide I40-58 Kinase Assay View IRS1 (Y608) Peptide
siRNA Sets IRS1 siRNA Set I I40-911 View IRS1 siRNA Set I
Kinase Inhibitors K252A K10-900D View K252A
Kinase Inhibitors K252B K10-900E View K252B
siRNA Sets KDR siRNA Set I K01-911 View KDR siRNA Set I
Active Kinases KDR, Active K01-11G Kinase Assay, Western Blot View KDR, Active
Kinase Inhibitors Lapatinib E10-900D View Lapatinib
Growth Factors Leptin L833-40N Cell Assay View Leptin
siRNA Sets Leptin siRNA Set I L833-911 View Leptin siRNA Set I
Kinase Inhibitors Lestaurtinib F12-901 View Lestaurtinib
Kinase Inhibitors LY-294002 P27-900C View LY-294002
siRNA Sets LYN A siRNA Set I L13-911 View LYN A siRNA Set I
Active Kinases LYN A, Active L13-18G Kinase Assay, Western Blot View LYN A, Active
siRNA Sets LYN B siRNA Set I L13-911B View LYN B siRNA Set I
Active Kinases LYN B, Active L13-10G Kinase Assay, Western Blot View LYN B, Active
Kinase Inhibitors LYS6K2 R15-900 View LYS6K2
Cell Cycle Proteins MDM2 (1-118) Protein M45-31BH Western Blot View MDM2 (1-118) Protein
Cell Cycle Proteins MDM2 Protein M45-31G Western Blot View MDM2 Protein
siRNA Sets MDM2 siRNA Set I M45-911B View MDM2 siRNA Set I
Cell Cycle Proteins MDM4 (1-137) Protein M47-31BH Western Blot View MDM4 (1-137) Protein
siRNA Sets MDM4 siRNA Set I M47-911 View MDM4 siRNA Set I
Peptide Substrates Modified AKT Substrate A05-58B Kinase Assay View Modified AKT Substrate
Peptide Substrates Modified AKT Substrate II A05-58C Kinase Assay View Modified AKT Substrate II
Peptide Substrates Modified SGKtide S08-58B Kinase Assay View Modified SGKtide
siRNA Sets MST1 siRNA Set I S25-911 View MST1 siRNA Set I
Active Kinases MST1, Active S25-10G Kinase Assay, Western Blot View MST1, Active
siRNA Sets MST3 siRNA Set I S42-911 View MST3 siRNA Set I
Active Kinases MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
siRNA Sets MST4 siRNA Set I M59-911 View MST4 siRNA Set I
Active Kinases MST4, Active M59-10G Kinase Assay, Western Blot View MST4, Active
siRNA Sets mTOR siRNA Set I F17-911 View mTOR siRNA Set I
Transcription Proteins NFKB2 Protein N13-31G Western Blot View NFKB2 Protein
siRNA Sets NFKB2 siRNA Set I N13-911B View NFKB2 siRNA Set I
Active Kinase Mutants NPM1-ALK Mutant (F1174L), Active A19-19EG Kinase Assay View NPM1-ALK Mutant (F1174L), Active
Active Kinase Mutants NPM1-ALK Mutant, Active A19-19BG Kinase Assay View NPM1-ALK Mutant, Active
Kinase Inhibitors NVP-BEZ235 F17-900 View NVP-BEZ235
siRNA Sets p70S6K siRNA Set I R21-911 View p70S6K siRNA Set I
Active Kinases p70S6K, Active R21-10H Kinase Assay, Western Blot View p70S6K, Active
Unactive Kinases p70S6K, Unactive R21-14H Western Blot View p70S6K, Unactive
siRNA Sets p70S6Kb siRNA Set I R22-911 View p70S6Kb siRNA Set I
Active Kinases p70S6Kb, Active R22-10G Kinase Assay, Western Blot View p70S6Kb, Active
Unactive Kinases p70S6Kb, Unactive R22-14G Kinase Assay, Western Blot View p70S6Kb, Unactive
Kinase Protein p70S6KL1 Protein R25-34G Western Blot View p70S6KL1 Protein
siRNA Sets p70S6KL1 siRNA Set I R25-911 View p70S6KL1 siRNA Set I
Growth Factors PDGF P841-40N Cell Assay View PDGF
siRNA Sets PDGF siRNA Set I P841-911 View PDGF siRNA Set I
Active Kinase Mutants PDGFR alpha Mutant (D842V), Active P12-12BG Kinase Assay View PDGFR alpha Mutant (D842V), Active
Active Kinase Mutants PDGFR alpha Mutant (T674I), Active P12-12CG Kinase Assay View PDGFR alpha Mutant (T674I), Active
siRNA Sets PDGFR alpha siRNA Set I P12-911 View PDGFR alpha siRNA Set I
Active Kinases PDGFR alpha, Active P12-11G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR alpha, Active P12-18G Kinase Assay, Western Blot View PDGFR alpha, Active
siRNA Sets PDGFR beta siRNA Set I P13-911 View PDGFR beta siRNA Set I
Active Kinases PDGFR beta, Active P13-11G Kinase Assay, Western Blot View PDGFR beta, Active
siRNA Sets PDK1 siRNA Set I P14-911 View PDK1 siRNA Set I
Active Kinases PDK1, Active P14-10H Kinase Assay, Western Blot View PDK1, Active
Peptide Substrates PDKtide P10-58 Kinase Assay View PDKtide
Cellular Proteins PHLPP2 Protein P72-21G Phosphatase Assay, Western Blot View PHLPP2 Protein
siRNA Sets PHLPP2 siRNA Set I P72-911 View PHLPP2 siRNA Set I
Active Lipid Kinases PI3K (p110 alpha (E545K)/p85 alpha), Active P27-152H Kinase Assay View PI3K (p110 alpha (E545K)/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha (N345K)/p85 alpha), Active P27-122CH Kinase Assay View PI3K (p110 alpha (N345K)/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha(E542K)/p85) alpha, Active P27-122DH Kinase Assay View PI3K (p110 alpha(E542K)/p85) alpha, Active
siRNA Sets PI3K (p110 alpha) siRNA Set I P27-911 View PI3K (p110 alpha) siRNA Set I
Active Lipid Kinases PI3K (p110 alpha/p55 gamma), Active P27-102CH Kinase Assay View PI3K (p110 alpha/p55 gamma), Active
Active Kinases PI3K (p110 alpha/p55 gamma), Active P27-10CH Kinase Assay, Western Blot View PI3K (p110 alpha/p55 gamma), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-102G Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-102H Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-10G Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-10H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-182H Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-18H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
siRNA Sets PI3K (p110 beta) siRNA Set I P28-911 View PI3K (p110 beta) siRNA Set I
Active Lipid Kinases PI3K (p110 beta/p85 alpha), Active P28-102H Kinase Assay View PI3K (p110 beta/p85 alpha), Active
Active Kinases PI3K (p110 beta/p85 alpha), Active P28-10H Kinase Assay, Western Blot View PI3K (p110 beta/p85 alpha), Active
Active Lipid Kinases PI3K (p110 beta/p85 beta), Active P28-102BH Kinase Assay View PI3K (p110 beta/p85 beta), Active
Active Kinases PI3K (p110 beta/p85 beta), Active P28-10BH Kinase Assay, Western Blot View PI3K (p110 beta/p85 beta), Active
siRNA Sets PI3K (p110 delta) siRNA Set I P30-911 View PI3K (p110 delta) siRNA Set I
Active Lipid Kinases PI3K (p110 delta/p85 alpha), Active P30-102H Kinase Assay View PI3K (p110 delta/p85 alpha), Active
Active Kinases PI3K (p110 delta/p85 alpha), Active P30-10H Kinase Assay, Western Blot View PI3K (p110 delta/p85 alpha), Active
siRNA Sets PI3K (p120 gamma) siRNA Set I P29-911B View PI3K (p120 gamma) siRNA Set I
Active Lipid Kinases PI3K (p120 gamma), Active P29-102H Kinase Assay View PI3K (p120 gamma), Active
Active Kinases PI3K (p120 gamma), Active P29-10H Kinase Assay, Western Blot View PI3K (p120 gamma), Active
Cellular Proteins PI3K (p55 gamma) Protein P31-30CH Western Blot View PI3K (p55 gamma) Protein
siRNA Sets PI3K (p55 gamma) siRNA Set I P31-911B View PI3K (p55 gamma) siRNA Set I
Cellular Proteins PI3K (p65 alpha) Protein P31-31H Western Blot View PI3K (p65 alpha) Protein
Cellular Proteins PI3K (p85 alpha) Protein P31-30H Kinase Assay, Western Blot View PI3K (p85 alpha) Protein
siRNA Sets PI3K (p85 alpha) siRNA Set I P31-911C View PI3K (p85 alpha) siRNA Set I
Cellular Proteins PI3K (p85 beta) Protein P31-30BH Kinase Assay, Western Blot View PI3K (p85 beta) Protein
siRNA Sets PI3K (p85 beta) siRNA Set I P31-911D View PI3K (p85 beta) siRNA Set I
Active Kinase Mutants PI3K Mutant (p110 alpha(E542K)/p85 alpha), Active P27-12DH Kinase Assay, Western Blot View PI3K Mutant (p110 alpha(E542K)/p85 alpha), Active
Active Kinase Mutants PI3K Mutant (p110 alpha(E545K)/p85 alpha), Active P27-15H Kinase Assay View PI3K Mutant (p110 alpha(E545K)/p85 alpha), Active
Active Kinase Mutants PI3K Mutant (p110alpha(N345K)/p85alpha), Active P27-12CH Kinase Assay, Western Blot View PI3K Mutant (p110alpha(N345K)/p85alpha), Active
siRNA Sets PI4K2A siRNA Set I P21-911 View PI4K2A siRNA Set I
Active Lipid Kinases PI4K2A, Active P21-102G Kinase Assay View PI4K2A, Active
Active Kinases PI4K2A, Active P21-10G Kinase Assay, Western Blot View PI4K2A, Active
siRNA Sets PI4K2B siRNA Set I P22-911B View PI4K2B siRNA Set I
Active Lipid Kinases PI4K2B, Active P22-102G Kinase Assay View PI4K2B, Active
Active Kinases PI4K2B, Active P22-10G Kinase Assay, Western Blot View PI4K2B, Active
Kinase Protein PI4KA Protein P31-30G Western Blot View PI4KA Protein
siRNA Sets PI4KA siRNA Set I P31-911 View PI4KA siRNA Set I
Active Lipid Kinases PI4KA, Active P31-102G Kinase Assay View PI4KA, Active
siRNA Sets PI4KB siRNA Set I P32-911 View PI4KB siRNA Set I
Active Lipid Kinases PI4KB, Active P32-102G Kinase Assay View PI4KB, Active
Active Kinases PI4KB, Active P32-10G Kinase Assay, Western Blot View PI4KB, Active
Kinase Inhibitors Picropodophyllotoxin I02-901 View Picropodophyllotoxin
siRNA Sets PIK3C2A siRNA Set I P23-911 View PIK3C2A siRNA Set I
Active Lipid Kinases PIK3C2A, Active P23-112G Kinase Assay View PIK3C2A, Active
Active Kinases PIK3C2A, Active P23-11G Kinase Assay, Western Blot View PIK3C2A, Active
Kinase Protein PIK3C2B Protein P24-31BG Western Blot View PIK3C2B Protein
siRNA Sets PIK3C2B siRNA Set I P24-911 View PIK3C2B siRNA Set I
Active Lipid Kinases PIK3C2B, Active P24-112BG Kinase Assay View PIK3C2B, Active
siRNA Sets PIK3C2G siRNA Set I P25-911 View PIK3C2G siRNA Set I
Active Lipid Kinases PIK3C2G, Active P25-112G Kinase Assay View PIK3C2G, Active
Active Kinases PIK3C2G, Active P25-11G Kinase Assay, Western Blot View PIK3C2G, Active
siRNA Sets PIK3C3 (Vps34) siRNA Set I P26-911 View PIK3C3 (Vps34) siRNA Set I
Active Lipid Kinases PIK3C3 (Vps34), Active P26-102G Kinase Assay View PIK3C3 (Vps34), Active
Active Kinases PIK3C3 (Vps34), Active P26-10G Kinase Assay, Western Blot View PIK3C3 (Vps34), Active
siRNA Sets PIP4K2A siRNA Set I P76-911 View PIP4K2A siRNA Set I
Active Lipid Kinases PIP4K2A, Active P76-102AG Kinase Assay View PIP4K2A, Active
Active Kinases PIP4K2A, Active P76-10AG Kinase Assay, Western Blot View PIP4K2A, Active
Kinase Protein PIP4K2B Protein P76-30BG Western Blot View PIP4K2B Protein
siRNA Sets PIP4K2B siRNA Set I P76-911B View PIP4K2B siRNA Set I
Active Lipid Kinases PIP4K2B, Active P76-102BG Kinase Assay View PIP4K2B, Active
Kinase Protein PIP4K2C Protein P76-30CG Western Blot View PIP4K2C Protein
siRNA Sets PIP4K2C siRNA Set I P76-911C View PIP4K2C siRNA Set I
Active Lipid Kinases PIP4K2C, Active P76-102CG Kinase Assay View PIP4K2C, Active
siRNA Sets PIP5K1A siRNA Set I P16-911 View PIP5K1A siRNA Set I
Active Lipid Kinases PIP5K1A, Active P16-102AG Kinase Assay View PIP5K1A, Active
Active Kinases PIP5K1A, Active P16-10AG Kinase Assay, Western Blot View PIP5K1A, Active
siRNA Sets PIP5K1B siRNA Set I P16-911B View PIP5K1B siRNA Set I
Active Lipid Kinases PIP5K1B, Active P16-102BG Kinase Assay View PIP5K1B, Active
Active Kinases PIP5K1B, Active P16-10BG Kinase Assay, Western Blot View PIP5K1B, Active
siRNA Sets PIP5K1C siRNA Set I P16-911C View PIP5K1C siRNA Set I
Active Lipid Kinases PIP5K1C, Active P16-102CG Kinase Assay View PIP5K1C, Active
Active Kinases PIP5K1C, Active P16-10CG Kinase Assay, Western Blot View PIP5K1C, Active
Active Lipid Kinases PIP5K3 (PIKFYVE), Active P17-112BG Kinase Assay View PIP5K3 (PIKFYVE), Active
Active Kinases PIP5K3 (PIKFYVE), Active P17-11BG Kinase Assay, Western Blot View PIP5K3 (PIKFYVE), Active
Kinase Protein PIP5K3 Protein P17-31G Western Blot View PIP5K3 Protein
siRNA Sets PIP5K3 siRNA Set I P17-911 View PIP5K3 siRNA Set I
Kinase Inhibitors PKC-412 K10-900B View PKC-412
Active Phosphatases PP2A alpha/PPP2R1A Complex, Active P16-20BH Phosphatase Assay, Western Blot View PP2A alpha/PPP2R1A Complex, Active
Cellular Proteins PTEN Protein P23-34G Western Blot View PTEN Protein
siRNA Sets PTEN siRNA Set I P23-911B View PTEN siRNA Set I
Active Phosphatases PTEN, Active P23-20G Phosphatase Assay, Western Blot View PTEN, Active
Kinase Inhibitors PX-866 P27-900 View PX-866
Kinase Inhibitors Rapamycin F17-901 View Rapamycin
siRNA Sets REL A siRNA Set I R29-911 View REL A siRNA Set I
G-Proteins RGS1 Protein R39-30H Western Blot View RGS1 Protein
siRNA Sets RGS1 siRNA Set I R39-911 View RGS1 siRNA Set I
Kinase Protein RIOK1 Protein R04-34G Western Blot View RIOK1 Protein
Kinase Protein RIOK2 Protein R05-34G Western Blot View RIOK2 Protein
Kinase Protein RIOK3 Protein R06-34G Western Blot View RIOK3 Protein
siRNA Sets RON siRNA Set I M58-911 View RON siRNA Set I
Active Kinases RON, Active M58-11G Kinase Assay, Western Blot View RON, Active
siRNA Sets RSK4 siRNA Set I R20-911 View RSK4 siRNA Set I
Active Kinases RSK4, Active R20-10G Kinase Assay, Western Blot View RSK4, Active
Peptide Substrates S6K Substrate S05-58 Kinase Assay View S6K Substrate
Kinase Inhibitors SC-514 I03-901 View SC-514
Chemokines SDF-1 S821-40N Cell Assay View SDF-1
siRNA Sets SDF-1 siRNA Set I S821-911 View SDF-1 siRNA Set I
siRNA Sets SGK1 siRNA Set I S06-911 View SGK1 siRNA Set I
Active Kinases SGK1, Active S06-11G Kinase Assay, Western Blot View SGK1, Active
Unactive Kinases SGK1, Unactive S06-15G Kinase Assay, Western Blot View SGK1, Unactive
siRNA Sets SGK2 siRNA Set I S07-911 View SGK2 siRNA Set I
Active Kinases SGK2, Active S07-10G Kinase Assay, Western Blot View SGK2, Active
Unactive Kinases SGK2, Unactive S07-14G Kinase Assay, Western Blot View SGK2, Unactive
siRNA Sets SGK3 siRNA Set I S08-911 View SGK3 siRNA Set I
Active Kinases SGK3, Active S08-10G Kinase Assay, Western Blot View SGK3, Active
Unactive Kinases SGK3, Unactive S08-14G Kinase Assay, Western Blot View SGK3, Unactive
Kinase Protein SGK494 Protein S57-34G Kinase Assay View SGK494 Protein
Peptide Substrates SGKtide S08-58 Kinase Assay View SGKtide
Active Phosphatases SHIP1, Active P08-20G Phosphatase Assay, Western Blot View SHIP1, Active
Active Phosphatases SHIP2, Active P09-20G Phosphatase Assay, Western Blot View SHIP2, Active
Transcription Proteins SMAD1 Protein S10-30G Kinase Assay, Western Blot View SMAD1 Protein
siRNA Sets SMAD1 siRNA Set I S10-911 View SMAD1 siRNA Set I
Transcription Proteins SMAD2 (del SXS) Protein S11-31G Western Blot View SMAD2 (del SXS) Protein
Transcription Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
siRNA Sets SMAD2 siRNA Set I S11-911B View SMAD2 siRNA Set I
Transcription Proteins SMAD3 (del SXS) Protein S12-31G Western Blot View SMAD3 (del SXS) Protein
Transcription Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
siRNA Sets SMAD3 siRNA Set I S12-911B View SMAD3 siRNA Set I
Transcription Proteins SMAD4 Protein S13-30G Kinase Assay, Western Blot View SMAD4 Protein
siRNA Sets SMAD4 siRNA Set I S13-911 View SMAD4 siRNA Set I
Transcription Proteins SMAD5 Protein S14-30G Kinase Assay, Western Blot View SMAD5 Protein
siRNA Sets SMAD5 siRNA Set I S14-911B View SMAD5 siRNA Set I
Transcription Proteins SMAD9 Protein S17-30G Western Blot View SMAD9 Protein
siRNA Sets SMAD9 siRNA Set I S17-911 View SMAD9 siRNA Set I
Kinase Inhibitors Staurosporine K10-900 View Staurosporine
siRNA Sets STK3 siRNA Set I S24-911 View STK3 siRNA Set I
Active Kinases STK3, Active S24-10G Kinase Assay, Western Blot View STK3, Active
Kinase Inhibitors Sunitinib malate F11-900G View Sunitinib malate
siRNA Sets SYK siRNA Set I S52-911B View SYK siRNA Set I
Active Kinases SYK, Active S52-10G Kinase Assay, Western Blot View SYK, Active
siRNA Sets TAB1 siRNA Set I T01-911 View TAB1 siRNA Set I
siRNA Sets TAK1 siRNA Set I M15-911 View TAK1 siRNA Set I
Active Kinases TAK1-TAB1, Active M15-13G Kinase Assay, Western Blot View TAK1-TAB1, Active
Active Kinase Mutants TFG-ALK Mutant, Active A19-19CG Kinase Assay View TFG-ALK Mutant, Active
Active Kinase Mutants TFG-TRKA Mutant (TRK-T3), Active N16-19CG Kinase Assay View TFG-TRKA Mutant (TRK-T3), Active
Growth Factors TGFB1 T831-40N Cell Assay View TGFB1
siRNA Sets TGFB1 siRNA Set I T831-911 View TGFB1 siRNA Set I
Growth Factors TGFB3 T833-40CN Cell Assay View TGFB3
siRNA Sets TGFB3 siRNA Set I T833-911 View TGFB3 siRNA Set I
Active Kinases TGFBR1 (ALK5), Active T07-11BG Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Active Kinases TGFBR1 (ALK5), Active T07-11G Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Active Kinase Mutants TGFBR1 Mutant (T204D), Active T07-13G Kinase Assay View TGFBR1 Mutant (T204D), Active
Peptide Substrates TGFBR1 Peptide T36-58 Peptide Substrate View TGFBR1 Peptide
siRNA Sets TGFBR1 siRNA Set I T07-911B View TGFBR1 siRNA Set I
Unactive Kinases TGFBR1, Unactive T07-35G Kinase Assay, Western Blot View TGFBR1, Unactive
siRNA Sets TGFBR2 siRNA Set I T08-911B View TGFBR2 siRNA Set I
Active Kinases TGFBR2, Active T08-11BG Kinase Assay, Western Blot View TGFBR2, Active
Active Kinases TGFBR2, Active T08-11G Kinase Assay, Western Blot View TGFBR2, Active
Cytokines TNF-alpha T860-40N Cell Assay View TNF-alpha
siRNA Sets TNF-alpha siRNA Set I T860-911 View TNF-alpha siRNA Set I
Cytokines TNFB T861-40N Cell Assay View TNFB
siRNA Sets TNFB siRNA Set I T861-911 View TNFB siRNA Set I
Adaptor Proteins TRAF1 Protein T56-30G Western Blot View TRAF1 Protein
Adaptor Proteins TRAF2 Protein T57-30G Western Blot View TRAF2 Protein
siRNA Sets TRAF2 siRNA Set I T57-911 View TRAF2 siRNA Set I
siRNA Sets TRAF3 siRNA Set I T58-911 View TRAF3 siRNA Set I
Cytokines TRAIL T880-40N Cell Assay View TRAIL
siRNA Sets TRAIL siRNA Set I T880-911 View TRAIL siRNA Set I
Kinase Inhibitors Wortmannin P27-900B View Wortmannin
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Inhibitors A83-01 A09-900 View A83-01
Assay Reagents Acetyltransferase Assay Buffer A01-09 Acetyltransferase Assay View Acetyltransferase Assay Buffer
siRNA Sets AFX siRNA Set I A42-911 View AFX siRNA Set I
Kinase Inhibitors AG-1296 P12-900 View AG-1296
Kinase Inhibitors AG-1478 E10-900B View AG-1478
Kinase Inhibitors AG-879 N28-909B View AG-879
Peptide Substrates AKT (PKB) Substrate A05-58 Kinase Assay View AKT (PKB) Substrate
Peptide Substrates AKT (SGK) Substrate A08-58 Kinase Assay View AKT (SGK) Substrate
Active Kinase Mutants AKT1 Mutant (E17K), Active A16-12G Kinase Assay View AKT1 Mutant (E17K), Active
Active Kinases AKT1, Active A16-10G Kinase Assay, Western Blot View AKT1, Active
Unactive Kinases AKT1, Unactive A16-14G Kinase Assay, Western Blot View AKT1, Unactive
siRNA Sets AKT1/PKB alpha siRNA Set I A16-911 View AKT1/PKB alpha siRNA Set I
Active Kinase Mutants AKT2 Mutant (E17K), Active A17-12G Kinase Assay View AKT2 Mutant (E17K), Active
Active Kinase Mutants AKT2 Mutant (R274H), Active A17-12BG Kinase Assay View AKT2 Mutant (R274H), Active
Active Kinases AKT2, Active A17-10G Kinase Assay, Western Blot View AKT2, Active
Active Kinases AKT2, Active A17-10H Kinase Assay, Western Blot View AKT2, Active
Unactive Kinases AKT2, Unactive A17-14G Kinase Assay, Western Blot View AKT2, Unactive
Unactive Kinases AKT2, Unactive A17-15H Kinase Assay, Western Blot View AKT2, Unactive
siRNA Sets AKT2/PKB beta siRNA Set I A17-911 View AKT2/PKB beta siRNA Set I
Active Kinase Mutants AKT3 Mutant (E17K), Active A18-12G Kinase Assay View AKT3 Mutant (E17K), Active
Active Kinase Mutants AKT3 Mutant (G171R), Active A18-12BG Kinase Assay View AKT3 Mutant (G171R), Active
siRNA Sets AKT3 siRNA Set I A18-911 View AKT3 siRNA Set I
Active Kinases AKT3, Active A18-10G Kinase Assay, Western Blot View AKT3, Active
Unactive Kinases AKT3, Unactive A18-14G Kinase Assay, Western Blot View AKT3, Unactive
Active Kinase Mutants ALK Mutant (C1156Y), Active A19-12DG Kinase Assay View ALK Mutant (C1156Y), Active
Active Kinase Mutants ALK Mutant (F1174L), Active A19-12EG Kinase Assay View ALK Mutant (F1174L), Active
Active Kinase Mutants ALK Mutant (F1174S), Active A19-12FG Kinase Assay View ALK Mutant (F1174S), Active
Active Kinase Mutants ALK Mutant (G1202R), Active A19-12HG Kinase Assay View ALK Mutant (G1202R), Active
Active Kinase Mutants ALK Mutant (G1269A), Active A19-12JG Kinase Assay View ALK Mutant (G1269A), Active
Active Kinase Mutants ALK Mutant (G1269S), Active A19-12KG Kinase Assay View ALK Mutant (G1269S), Active
Active Kinase Mutants ALK Mutant (L1152R), Active A19-12CG Kinase Assay View ALK Mutant (L1152R), Active
Active Kinase Mutants ALK Mutant (L1196M), Active A19-12GG Kinase Assay View ALK Mutant (L1196M), Active
Active Kinase Mutants ALK Mutant (R1275Q), Active A19-12LG Kinase Assay View ALK Mutant (R1275Q), Active
Active Kinase Mutants ALK Mutant (S1206R), Active A19-12IG Kinase Assay View ALK Mutant (S1206R), Active
Active Kinase Mutants ALK Mutant (T1151M), Active A19-12BG Kinase Assay View ALK Mutant (T1151M), Active
Active Kinase Mutants ALK Mutant (T1151_L1152insT), Active A19-12G Kinase Assay View ALK Mutant (T1151_L1152insT), Active
Active Kinases ALK, Active A19-11G Kinase Assay, Western Blot View ALK, Active
siRNA Sets ALK1 siRNA Set I A09-911 View ALK1 siRNA Set I
Active Kinases ALK1, Active A09-11G Kinase Assay, Western Blot View ALK1, Active
Active Kinase Mutants ALK2 Mutant (PF197_198L), Active A06-12FG Kinase Assay View ALK2 Mutant (PF197_198L), Active
Active Kinase Mutants ALK2 Mutant (Q207D), Active A06-13CG Kinase Assay View ALK2 Mutant (Q207D), Active
Active Kinase Mutants ALK2 Mutant (Q207E), Active A06-13DG Kinase Assay View ALK2 Mutant (Q207E), Active
Active Kinase Mutants ALK2 Mutant (R206H), Active A06-12BG Kinase Assay View ALK2 Mutant (R206H), Active
siRNA Sets ALK2 siRNA Set I A06-911 View ALK2 siRNA Set I
Active Kinases ALK2, Active A06-11G Kinase Assay, Western Blot View ALK2, Active
siRNA Sets ALK3 (BMPR1A) siRNA Set I B04-911 View ALK3 (BMPR1A) siRNA Set I
Active Kinases ALK3 (BMPR1A), Active B04-11G Kinase Assay, Western Blot View ALK3 (BMPR1A), Active
Active Kinase Mutants ALK3 Mutant (Q233D), Active B04-12BG Kinase Assay View ALK3 Mutant (Q233D), Active
Active Kinase Mutants ALK3 Mutant (R486Q), Active B04-12CG Kinase Assay View ALK3 Mutant (R486Q), Active
Active Kinases ALK4, Active A07-11G Kinase Assay, Western Blot View ALK4, Active
siRNA Sets ALK6 (BMPR1B) siRNA Set I B05-911 View ALK6 (BMPR1B) siRNA Set I
Active Kinases ALK6 (BMPR1B), Active B05-11G Kinase Assay, Western Blot View ALK6 (BMPR1B), Active
Kinase Protein ALK7 Protein A08-35G Western Blot View ALK7 Protein
siRNA Sets ALK7 siRNA Set I A08-911 View ALK7 siRNA Set I
Kinase Inhibitors Alsterpaullone G09-901C View Alsterpaullone
Primary Antibodies Anti-4EBP1 E35-563R WB, ELISA, ICC View Anti-4EBP1
Primary Antibodies Anti-AFX A42-63R WB View Anti-AFX
Primary Antibodies Anti-AKT1 A16-60M WB View Anti-AKT1
Primary Antibodies Anti-AKT1 A16-63CR WB, ELISA, IF, IHC View Anti-AKT1
Primary Antibodies Anti-AKT2/3 A17-63BR WB View Anti-AKT2/3
Isoform Specific Antibodies Anti-AKT3 A18-63R WB View Anti-AKT3
Primary Antibodies Anti-ALK2 A06-63R WB, ELISA View Anti-ALK2
Primary Antibodies Anti-ALK4 A07-63R WB, ELISA View Anti-ALK4
Primary Antibodies Anti-ALK7 A08-63R WB, ELISA View Anti-ALK7
Primary Antibodies Anti-BAG1 B05-363BR WB, ELISA, IF, IHC View Anti-BAG1
Primary Antibodies Anti-BAG1 B05-363R WB, ELISA View Anti-BAG1
Primary Antibodies Anti-BAX B14-363R WB, ELISA, ICC, IF View Anti-BAX
Primary Antibodies Anti-BMPR2 B06-63R WB, ELISA, IHC View Anti-BMPR2
Primary Antibodies Anti-DYRK1A D09-63R WB, ELISA, IF View Anti-DYRK1A
Primary Antibodies Anti-DYRK2 D10-63R WB, ELISA, ICC, IF View Anti-DYRK2
Primary Antibodies Anti-EGFR E10-63BR WB View Anti-EGFR
Primary Antibodies Anti-EGFR E10-63R WB View Anti-EGFR
Primary Antibodies Anti-FLT3 F12-63R WB, ELISA, IF View Anti-FLT3
Isoform Specific Antibodies Anti-GSK3 alpha G08-63R WB View Anti-GSK3 alpha
Primary Antibodies Anti-GSK3 alpha/beta G09-63R WB View Anti-GSK3 alpha/beta
Isoform Specific Antibodies Anti-GSK3 beta G09-60M WB View Anti-GSK3 beta
Primary Antibodies Anti-HER2 E27-63R WB, ELISA, IF, IHC View Anti-HER2
Isoform Specific Antibodies Anti-HSP90 beta H36-63R WB View Anti-HSP90 beta
Primary Antibodies Anti-IKK alpha C51-63BR WB, ELISA, ICC, IF View Anti-IKK alpha
Primary Antibodies Anti-IKK alpha C51-63CR WB, ELISA, ICC View Anti-IKK alpha
Primary Antibodies Anti-IKK alpha C51-63R WB, ELISA, ICC, IF View Anti-IKK alpha
Primary Antibodies Anti-IKK beta I03-63R WB, ELISA, ICC, IF View Anti-IKK beta
Primary Antibodies Anti-IKK epsilon I04-63R WB, ELISA, IHC View Anti-IKK epsilon
Primary Antibodies Anti-IKK gamma I25-63R WB, ELISA, ICC View Anti-IKK gamma
Primary Antibodies Anti-IRS1 I40-363R WB, ELISA, ICC, IF View Anti-IRS1
Primary Antibodies Anti-mTOR F17-63BR WB, ELISA, ICC View Anti-mTOR
Primary Antibodies Anti-mTOR F17-63R WB View Anti-mTOR
Primary Antibodies Anti-NF-kB p105 N12-63R WB View Anti-NF-kB p105
Primary Antibodies Anti-p70S6K R21-63BR WB View Anti-p70S6K
Primary Antibodies Anti-p70S6K R21-63R WB View Anti-p70S6K
Primary Antibodies Anti-PDGFB P842-63R WB, ELISA View Anti-PDGFB
Primary Antibodies Anti-PHLPP1 P71-263R WB, ELISA View Anti-PHLPP1
Primary Antibodies Anti-PHLPP2 P72-263R WB, ELISA View Anti-PHLPP2
Phospho Specific Antibodies Anti-phospho-14-3-3 beta (Ser58) Y71-365R WB, IHC View Anti-phospho-14-3-3 beta (Ser58)
Phospho Specific Antibodies Anti-phospho-4EBP1 (Thr45) E35-365R WB, IHC View Anti-phospho-4EBP1 (Thr45)
Phospho Specific Antibodies Anti-phospho-AKT1/2/3 (Ser473) A16-65BR WB, IHC View Anti-phospho-AKT1/2/3 (Ser473)
Phospho Specific Antibodies Anti-phospho-AKT1/2/3 (Thr308) A16-65R WB, IHC View Anti-phospho-AKT1/2/3 (Thr308)
Phospho Specific Antibodies Anti-phospho-EGFR (Thr678) E10-65BR WB View Anti-phospho-EGFR (Thr678)
Phospho Specific Antibodies Anti-phospho-EGFR (Thr693) E10-65CR WB View Anti-phospho-EGFR (Thr693)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1092) E10-65DR WB, IHC View Anti-phospho-EGFR (Tyr1092)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1110) E10-65ER WB View Anti-phospho-EGFR (Tyr1110)
Phospho Specific Antibodies Anti-phospho-EGFR (Tyr1197) E10-65FR WB, IHC View Anti-phospho-EGFR (Tyr1197)
Phospho Specific Antibodies Anti-phospho-GSK3 beta (Ser9) G09-652R WB View Anti-phospho-GSK3 beta (Ser9)
Phospho Specific Antibodies Anti-phospho-GSK3 beta (Ser9) G09-65R WB, IHC View Anti-phospho-GSK3 beta (Ser9)
Phospho Specific Antibodies Anti-phospho-HER2 (Tyr877) E27-65R WB, IHC View Anti-phospho-HER2 (Tyr877)
Phospho Specific Antibodies Anti-phospho-IRS1 (Ser312) I40-365R WB View Anti-phospho-IRS1 (Ser312)
Phospho Specific Antibodies Anti-phospho-IRS1 (Ser639) I40-365BR IHC View Anti-phospho-IRS1 (Ser639)
Phospho Specific Antibodies Anti-phospho-KDR (Tyr1214) K01-65BR IHC View Anti-phospho-KDR (Tyr1214)
Phospho Specific Antibodies Anti-phospho-KDR (Tyr951) K01-65R WB, IHC View Anti-phospho-KDR (Tyr951)
Phospho Specific Antibodies Anti-phospho-mTOR (Ser2448) F17-65R IHC View Anti-phospho-mTOR (Ser2448)
Phospho Specific Antibodies Anti-phospho-PDK1 (Ser241) P14-65R WB, IHC View Anti-phospho-PDK1 (Ser241)
Modification Antibodies Anti-Phosphoserine (Anti-pS) S95-65R WB, ELISA, IHC, IP View Anti-Phosphoserine (Anti-pS)
Modification Antibodies Anti-Phosphoserine (Anti-pS), Biotin Conjugated S95-65BR WB, ELISA View Anti-Phosphoserine (Anti-pS), Biotin Conjugated
Modification Antibodies Anti-Phosphothreonine (Anti-pT) T95-65R WB, ELISA, IHC, IP View Anti-Phosphothreonine (Anti-pT)
Modification Antibodies Anti-Phosphothreonine (Anti-pT), Biotin Conjugated T95-65BR WB, ELISA View Anti-Phosphothreonine (Anti-pT), Biotin Conjugated
Modification Antibodies Anti-Phosphotyrosine (Anti-pY) T96-65R WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY)
Modification Antibodies Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated T96-65BR WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated
Primary Antibodies Anti-PTEN P23-263BR WB, ELISA, IF View Anti-PTEN
Primary Antibodies Anti-PTEN P23-263R WB, ELISA View Anti-PTEN
Primary Antibodies Anti-Rel A R29-63BR WB View Anti-Rel A
Primary Antibodies Anti-Rel A R29-63R WB View Anti-Rel A
Primary Antibodies Anti-SGK1 S06-63R WB, ELISA, IF, IHC View Anti-SGK1
Isoform Specific Antibodies Anti-SMAD2 S11-63R WB View Anti-SMAD2
Primary Antibodies Anti-TAB1 T01-363R WB, ELISA, ICC, IF View Anti-TAB1
Primary Antibodies Anti-TAK1 M15-63R WB, ELISA, IF, IHC View Anti-TAK1
Primary Antibodies Anti-Trail T880-63R WB, ELISA, IHC View Anti-Trail
Kinase Inhibitors Apigenin K10-900C View Apigenin
Kinase Inhibitors AR-A014418 G09-901 View AR-A014418
Kinase Inhibitors AS-041164 P29-901 View AS-041164
Apoptosis Proteins BAG1 Protein B05-31G Western Blot View BAG1 Protein
siRNA Sets BAG1 siRNA Set I B05-911B View BAG1 siRNA Set I
Apoptosis Proteins BAX Protein B14-30G Western Blot View BAX Protein
siRNA Sets BAX siRNA Set I B14-911 View BAX siRNA Set I
Kinase Inhibitors BAY 11-7082 C51-900 View BAY 11-7082
Growth Factors BMP-2 B851-40N Cell Assay View BMP-2
siRNA Sets BMP-2 siRNA Set I B851-911 View BMP-2 siRNA Set I
Growth Factors BMP-4 B853-40N Cell Assay View BMP-4
siRNA Sets BMP-4 siRNA Set I B853-911 View BMP-4 siRNA Set I
Kinase Protein BMP2K Protein B03-11G Western Blot View BMP2K Protein
siRNA Sets BMP2K siRNA Set I B03-911B View BMP2K siRNA Set I
siRNA Sets BMPR2 siRNA Set I B06-911 View BMPR2 siRNA Set I
Active Kinases BMPR2, Active B06-11H Kinase Assay, Western Blot View BMPR2, Active
Kinase Protein CDK12 (CRKRS) Protein C62-35G Kinase Assay, Western Blot View CDK12 (CRKRS) Protein
Kinase Inhibitors CHIR-99021 G09-901B View CHIR-99021
Peptide Substrates Crosstide C51-58 Kinase Assay View Crosstide
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Inhibitors Deguelin A16-900B View Deguelin
Kinase Inhibitors DMPQ 2 HCl P13-901 View DMPQ 2 HCl
Dihydropyrimidinase DPYSL2 Protein D470-30BG Western Blot View DPYSL2 Protein
siRNA Sets DYRK1A siRNA Set I D09-911 View DYRK1A siRNA Set I
Active Kinases DYRK1A, Active D09-10G Kinase Assay, Western Blot View DYRK1A, Active
Active Kinases DYRK1B, Active D09-10BG Kinase Assay, Western Blot View DYRK1B, Active
siRNA Sets DYRK2 siRNA Set I D10-911 View DYRK2 siRNA Set I
Active Kinases DYRK2, Active D10-10G Kinase Assay, Western Blot View DYRK2, Active
siRNA Sets DYRK3 siRNA Set I D11-911 View DYRK3 siRNA Set I
Active Kinases DYRK3, Active D11-11G Kinase Assay, Western Blot View DYRK3, Active
Active Kinases DYRK4, Active D12-10G Kinase Assay, Western Blot View DYRK4, Active
Peptide Substrates DYRKtide D96-58 Kinase Assay View DYRKtide
siRNA Sets EEF2K siRNA Set I E01-911 View EEF2K siRNA Set I
Active Kinases EEF2K, Active E01-10G Kinase Assay, Western Blot View EEF2K, Active
EF2tide E01-58 View EF2tide
Peptide Substrates EF2tide E01-58 Kinase Assay View EF2tide
Active Kinase Mutants EGFR Mutant (A763_Y764insFHEA), Active E10-132BG Kinase Assay View EGFR Mutant (A763_Y764insFHEA), Active
Active Kinase Mutants EGFR Mutant (A763_Y764insFHEA), Active E10-13BG Kinase Assay View EGFR Mutant (A763_Y764insFHEA), Active
Kinase Mutant Proteins EGFR Mutant (A767_S768insTLA) Protein E10-13CG Kinase Assay View EGFR Mutant (A767_S768insTLA) Protein
Active Kinase Mutants EGFR Mutant (C775S T790M L858R), Active New Research Category E10-122D2G Kinase Assay View EGFR Mutant (C775S T790M L858R), Active
Active Kinase Mutants EGFR Mutant (C797A), Active E10-12RG Kinase Assay View EGFR Mutant (C797A), Active
Active Kinase Mutants EGFR Mutant (C797S L858R), Active E10-122ZG Kinase Assay View EGFR Mutant (C797S L858R), Active
Active Kinase Mutants EGFR Mutant (C797S), Active E10-122SG Kinase Assay View EGFR Mutant (C797S), Active
Active Kinase Mutants EGFR Mutant (C797S), Active E10-12SG Kinase Assay View EGFR Mutant (C797S), Active
Active Kinase Mutants EGFR Mutant (d746), Active E10-12IG Kinase Assay View EGFR Mutant (d746), Active
Active Kinase Mutants EGFR Mutant (d746-750 C775S T790M L858R), Active New Research Category E10-122E2G Kinase Assay View EGFR Mutant (d746-750 C775S T790M L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797A), Active E10-122C2G Kinase Assay View EGFR Mutant (d746-750 C797A), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797S), Active E10-122TG Kinase Assay View EGFR Mutant (d746-750 C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 C797S), Active E10-12TG Kinase Assay View EGFR Mutant (d746-750 C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S L858R), Active E10-122YG Kinase Assay View EGFR Mutant (d746-750 T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S), Active E10-122UG Kinase Assay View EGFR Mutant (d746-750 T790M C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M C797S), Active E10-12UG Kinase Assay View EGFR Mutant (d746-750 T790M C797S), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M L858R), Active E10-122XG Kinase Assay View EGFR Mutant (d746-750 T790M L858R), Active
Active Kinase Mutants EGFR Mutant (d746-750 T790M L978I), Active E10-122WG Kinase Assay View EGFR Mutant (d746-750 T790M L978I), Active
Kinase Mutant Proteins EGFR Mutant (d746-750 T790M) Protein E10-12KG Kinase Assay View EGFR Mutant (d746-750 T790M) Protein
Active Kinase Mutants EGFR Mutant (d746-750 T790M), Active E10-122KG Kinase Assay View EGFR Mutant (d746-750 T790M), Active
Active Kinase Mutants EGFR Mutant (d746-750), Active E10-122JG Kinase Assay View EGFR Mutant (d746-750), Active
Active Kinase Mutants EGFR Mutant (d746-750), Active E10-12JG Kinase Assay View EGFR Mutant (d746-750), Active
Active Kinase Mutants EGFR Mutant (d747-749 A750P), Active E10-12MG Kinase Assay View EGFR Mutant (d747-749 A750P), Active
Active Kinase Mutants EGFR Mutant (d747-749), Active E10-12LG Kinase Assay View EGFR Mutant (d747-749), Active
Active Kinase Mutants EGFR Mutant (d747-752 P753S), Active E10-12NG Kinase Assay View EGFR Mutant (d747-752 P753S), Active
Active Kinase Mutants EGFR Mutant (d752-759), Active E10-12OG Kinase Assay View EGFR Mutant (d752-759), Active
Active Kinase Mutants EGFR Mutant (D761Y), Active E10-12QG Kinase Assay View EGFR Mutant (D761Y), Active
Active Kinase Mutants EGFR Mutant (D770GY), Active E10-13KG Kinase Assay View EGFR Mutant (D770GY), Active
Active Kinase Mutants EGFR Mutant (D770_N771insGF) Protein E10-13IG Kinase Assay View EGFR Mutant (D770_N771insGF) Protein
Active Kinase Mutants EGFR Mutant (D770_N771insNPG), Active E10-132GG Kinase Assay View EGFR Mutant (D770_N771insNPG), Active
Active Kinase Mutants EGFR Mutant (D770_N771insNPG), Active E10-13GG Kinase Assay View EGFR Mutant (D770_N771insNPG), Active
Active Kinase Mutants EGFR Mutant (G719C), Active E10-12FG Kinase Assay View EGFR Mutant (G719C), Active
Active Kinase Mutants EGFR Mutant (G719D), Active E10-12GG Kinase Assay View EGFR Mutant (G719D), Active
Active Kinase Mutants EGFR Mutant (G719S), Active E10-12HG Kinase Assay View EGFR Mutant (G719S), Active
Active Kinase Mutants EGFR Mutant (H773_V774insAH) Protein E10-13PG Kinase Assay View EGFR Mutant (H773_V774insAH) Protein
Active Kinase Mutants EGFR Mutant (H773_V774insH) Protein E10-13RG Kinase Assay View EGFR Mutant (H773_V774insH) Protein
Kinase Mutant Proteins EGFR Mutant (H773_V774insNPH) Protein E10-13OG Kinase Assay View EGFR Mutant (H773_V774insNPH) Protein
Kinase Mutant Proteins EGFR Mutant (H773_V774insPH) Protein E10-13QG Kinase Assay View EGFR Mutant (H773_V774insPH) Protein
Active Kinase Mutants EGFR Mutant (L747S), Active E10-12PG Kinase Assay View EGFR Mutant (L747S), Active
Active Kinase Mutants EGFR Mutant (L858R), Active E10-122BG Kinase Assay View EGFR Mutant (L858R), Active
Active Kinase Mutants EGFR Mutant (L858R), Active E10-12BG Kinase Assay View EGFR Mutant (L858R), Active
Active Kinase Mutants EGFR Mutant (L861Q), Active E10-12CG Kinase Assay View EGFR Mutant (L861Q), Active
Active Kinase Mutants EGFR Mutant (P772_H773insNPH), Active E10-13MG Kinase Assay View EGFR Mutant (P772_H773insNPH), Active
Active Kinase Mutants EGFR Mutant (T790M C797S L858R), Active E10-122VG Kinase Assay View EGFR Mutant (T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (T790M C797S L858R), Active E10-12VG Kinase Assay View EGFR Mutant (T790M C797S L858R), Active
Active Kinase Mutants EGFR Mutant (T790M C797S), Active E10-122B2G Kinase Assay View EGFR Mutant (T790M C797S), Active
Active Kinase Mutants EGFR Mutant (T790M L858R), Active E10-122DG Kinase Assay View EGFR Mutant (T790M L858R), Active
Active Kinase Mutants EGFR Mutant (T790M L858R), Active E10-12DG Kinase Assay View EGFR Mutant (T790M L858R), Active
Active Kinase Mutants EGFR Mutant (T790M), Active E10-122EG Kinase Assay View EGFR Mutant (T790M), Active
Active Kinase Mutants EGFR Mutant (T790M), Active E10-12EG Kinase Assay View EGFR Mutant (T790M), Active
Kinase Mutant Proteins EGFR Mutant (V769_D770insASV) Protein E10-13DG Kinase Assay View EGFR Mutant (V769_D770insASV) Protein
Kinase Mutant Proteins EGFR Mutant (V769_D770insGE) Protein E10-13EG Kinase Assay View EGFR Mutant (V769_D770insGE) Protein
siRNA Sets EGFR siRNA Set I E10-911 View EGFR siRNA Set I
Active Kinases EGFR, Active E10-112G Kinase Assay, Western Blot View EGFR, Active
Active Kinases EGFR, Active E10-11G Kinase Assay, Western Blot View EGFR, Active
Kinase Inhibitors Erlotinib HCl E10-900C View Erlotinib HCl
siRNA Sets FAK siRNA Set I P91-911 View FAK siRNA Set I
Active Kinases FAK, Active P91-10G Kinase Assay, Western Blot View FAK, Active
Active Kinases FAK, Active P91-11H Kinase Assay, Western Blot View FAK, Active
Active Kinases FGFR1 (FLT2), Active F04-11G Kinase Assay, Western Blot View FGFR1 (FLT2), Active
Active Kinase Mutants FGFR1 Mutant (V561M), Active F04-13G Kinase Assay View FGFR1 Mutant (V561M), Active
siRNA Sets FGFR1 siRNA Set I F04-911 View FGFR1 siRNA Set I
Active Kinase Mutants FGFR1OP-FGFR1 Mutant, Active F04-19BG Kinase Assay View FGFR1OP-FGFR1 Mutant, Active
Active Kinase Mutants FGFR2 Mutant (E565G), Active F05-12CG Kinase Assay View FGFR2 Mutant (E565G), Active
Active Kinase Mutants FGFR2 Mutant (K526E), Active F05-12BG Kinase Assay View FGFR2 Mutant (K526E), Active
Active Kinase Mutants FGFR2 Mutant (K641R), Active F05-12DG Kinase Assay View FGFR2 Mutant (K641R), Active
Active Kinase Mutants FGFR2 Mutant (K659N), Active F05-12EG Kinase Assay View FGFR2 Mutant (K659N), Active
Active Kinase Mutants FGFR2 Mutant (N549H), Active F05-12G Kinase Assay View FGFR2 Mutant (N549H), Active
Active Kinase Mutants FGFR2 Mutant (R612T), Active F05-12GG Kinase Assay, Western Blot View FGFR2 Mutant (R612T), Active
Active Kinase Mutants FGFR2 Mutant (V564F), Active F05-12FG Kinase Assay, Western Blot View FGFR2 Mutant (V564F), Active
siRNA Sets FGFR2 siRNA Set I F05-911 View FGFR2 siRNA Set I
Active Kinases FGFR2, Active F05-11G Kinase Assay, Western Blot View FGFR2, Active
Active Kinase Mutants FGFR3 Mutant (G697C), Active F06-12FG Kinase Assay View FGFR3 Mutant (G697C), Active
Active Kinase Mutants FGFR3 Mutant (K650E), Active F06-12CG Kinase Assay View FGFR3 Mutant (K650E), Active
Active Kinase Mutants FGFR3 Mutant (K650M), Active F06-12DG Kinase Assay View FGFR3 Mutant (K650M), Active
Active Kinase Mutants FGFR3 Mutant (K650Q), Active F06-12EG Kinase Assay View FGFR3 Mutant (K650Q), Active
Active Kinase Mutants FGFR3 Mutant (V555M), Active F06-12GG Kinase Assay View FGFR3 Mutant (V555M), Active
siRNA Sets FGFR3 siRNA Set I F06-911 View FGFR3 siRNA Set I
Active Kinases FGFR3, Active F06-11G Kinase Assay, Western Blot View FGFR3, Active
Active Kinase Mutants FGFR4 Mutant (N535K), Active F07-12G Kinase Assay View FGFR4 Mutant (N535K), Active
Active Kinase Mutants FGFR4 Mutant (V550E), Active F07-12BG Kinase Assay View FGFR4 Mutant (V550E), Active
Active Kinase Mutants FGFR4 Mutant (V550L), Active F07-12CG Kinase Assay View FGFR4 Mutant (V550L), Active
Active Kinase Mutants FGFR4 Mutant (V550M), Active F07-12DG Kinase Assay View FGFR4 Mutant (V550M), Active
siRNA Sets FGFR4 siRNA Set I F07-911 View FGFR4 siRNA Set I
Active Kinases FGFR4, Active F07-11G Kinase Assay, Western Blot View FGFR4, Active
Active Kinase Mutants FIP1L1-PDGFR alpha Mutant, Active P12-19BG Kinase Assay View FIP1L1-PDGFR alpha Mutant, Active
Cellular Proteins FKBP1A Protein F37-30G Western Blot View FKBP1A Protein
siRNA Sets FKBP1A siRNA Set I F37-911 View FKBP1A siRNA Set I
siRNA Sets FLT1 siRNA Set I F11-911 View FLT1 siRNA Set I
Active Kinases FLT1, Active F11-11G Kinase Assay, Western Blot View FLT1, Active
Active Kinase Mutants FLT3 Mutant (D835Y), Active F12-12BG Kinase Assay View FLT3 Mutant (D835Y), Active
Active Kinase Mutants FLT3 Mutant (F594_R595insR), Active F12-12EG Kinase Assay View FLT3 Mutant (F594_R595insR), Active
Active Kinase Mutants FLT3 Mutant (F594_R595insREY), Active F12-12FG Kinase Assay View FLT3 Mutant (F594_R595insREY), Active
Active Kinase Mutants FLT3 Mutant (N676K), Active F12-12IG Kinase Assay View FLT3 Mutant (N676K), Active
Active Kinase Mutants FLT3 Mutant (R595_E596insEY), Active F12-12GG Kinase Assay View FLT3 Mutant (R595_E596insEY), Active
Active Kinase Mutants FLT3 Mutant (Y591-V592insVDFREYEYD), Active F12-12HG Kinase Assay View FLT3 Mutant (Y591-V592insVDFREYEYD), Active
siRNA Sets FLT3 siRNA Set I F12-911 View FLT3 siRNA Set I
Active Kinases FLT3, Active F12-11G Kinase Assay, Western Blot View FLT3, Active
Active Kinase Mutants FLT3-ITD-NPOS Mutant, Active F12-12DG Kinase Assay View FLT3-ITD-NPOS Mutant, Active
Active Kinase Mutants FLT3-ITD-W51 Mutant, Active F12-12CG Kinase Assay View FLT3-ITD-W51 Mutant, Active
siRNA Sets FLT4 siRNA Set I F13-911 View FLT4 siRNA Set I
Active Kinases FLT4, Active F13-11G Kinase Assay, Western Blot View FLT4, Active
Cellular Proteins FRS3 Protein F80-30G Kinase Assay, Western Blot View FRS3 Protein
siRNA Sets FRS3 siRNA Set I F80-911 View FRS3 siRNA Set I
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Inhibitors Gefitinib E10-900 View Gefitinib
Active GTPases/ATPases GNAI1, Active New Research Category G121-310G Enzyme Assay View GNAI1, Active
Active GTPases/ATPases GNAI2, Active New Research Category G122-310G Enzyme Assay View GNAI2, Active
Active GTPases/ATPases GNAI3, Active New Research Category G123-310G Enzyme Assay View GNAI3, Active
Peptide Substrates GS Peptide G60-58 Kinase Assay View GS Peptide
siRNA Sets GSK3 alpha siRNA Set I G08-911 View GSK3 alpha siRNA Set I
Active Kinases GSK3 alpha, Active G08-10G Kinase Assay, Western Blot View GSK3 alpha, Active
siRNA Sets GSK3 beta siRNA Set I G09-911 View GSK3 beta siRNA Set I
Active Kinases GSK3 beta, Active G09-10G Kinase Assay, Western Blot View GSK3 beta, Active
Active Kinases GSK3 beta, Active G09-10H Kinase Assay, Western Blot View GSK3 beta, Active
Unactive Kinases GSK3 beta, Unactive G09-14G Kinase Assay, Western Blot View GSK3 beta, Unactive
Peptide Substrates GSK3 Substrate G50-58 Kinase Assay View GSK3 Substrate
Kinase Inhibitors GW-441756 N28-909 View GW-441756
Kinase Protein H11 (HSP22) Protein H09-34G Western Blot View H11 (HSP22) Protein
Active Kinase Mutants HER2 Mutant (A775_G776insYVMA), Active E27-13BG Kinase Assay View HER2 Mutant (A775_G776insYVMA), Active
Active Kinase Mutants HER2 Mutant (d755-759), Active E27-12BG Kinase Assay View HER2 Mutant (d755-759), Active
Active Kinase Mutants HER2 Mutant (D769H), Active E27-12GG Kinase Assay View HER2 Mutant (D769H), Active
Active Kinase Mutants HER2 Mutant (D769Y), Active E27-12HG Kinase Assay View HER2 Mutant (D769Y), Active
Kinase Mutant Proteins HER2 Mutant (E719G) Protein E27-12CG Kinase Assay View HER2 Mutant (E719G) Protein
Kinase Mutant Proteins HER2 Mutant (E719K) Protein E27-12DG Kinase Assay View HER2 Mutant (E719K) Protein
Active Kinase Mutants HER2 Mutant (G776VC), Active E27-13EG Kinase Assay View HER2 Mutant (G776VC), Active
Active Kinase Mutants HER2 Mutant (I767M), Active E27-12NG Kinase Assay View HER2 Mutant (I767M), Active
Active Kinase Mutants HER2 Mutant (L755S), Active E27-12EG Kinase Assay View HER2 Mutant (L755S), Active
Active Kinase Mutants HER2 Mutant (L755W), Active E27-12FG Kinase Assay View HER2 Mutant (L755W), Active
Active Kinase Mutants HER2 Mutant (P780_Y781insGSP), Active E27-13DG Kinase Assay View HER2 Mutant (P780_Y781insGSP), Active
Active Kinase Mutants HER2 Mutant (R896C), Active E27-12KG Kinase Assay View HER2 Mutant (R896C), Active
Active Kinase Mutants HER2 Mutant (V777L), Active E27-12IG Kinase Assay View HER2 Mutant (V777L), Active
Active Kinase Mutants HER2 Mutant (V777_G778insCG), Active E27-13CG Kinase Assay View HER2 Mutant (V777_G778insCG), Active
Active Kinase Mutants HER2 Mutant (V842I), Active E27-12JG Kinase Assay View HER2 Mutant (V842I), Active
siRNA Sets HER2 siRNA Set I E27-911 View HER2 siRNA Set I
Peptide Substrates HER2 Substrate E27-58 Kinase Assay View HER2 Substrate
Active Kinases HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
siRNA Sets HER4 siRNA Set I E29-911 View HER4 siRNA Set I
Active Kinases HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Cell Stress & Chaperone Proteins HSP90 alpha Protein H36-50H Western Blot View HSP90 alpha Protein
Cell Stress & Chaperone Proteins HSP90 beta Protein H36-54H ATPase Assay, Western Blot View HSP90 beta Protein
siRNA Sets IGF1R siRNA Set I I02-911 View IGF1R siRNA Set I
Active Kinases IGF1R, Active I02-11H Kinase Assay, Western Blot View IGF1R, Active
Peptide Substrates IGF1Rtide I15-58 Kinase Assay View IGF1Rtide
Transcription Proteins IkBA Protein I20-30G Kinase Assay, Western Blot View IkBA Protein
Transcription Proteins IkBA Protein I20-31G Kinase Assay, Western Blot View IkBA Protein
siRNA Sets IkBalpha siRNA Set I I20-911 View IkBalpha siRNA Set I
Transcription Proteins IkBB Protein I21-30G Kinase Assay, Western Blot View IkBB Protein
siRNA Sets IkBbeta siRNA Set I I21-911 View IkBbeta siRNA Set I
siRNA Sets IKK alpha siRNA Set I C51-911 View IKK alpha siRNA Set I
Active Kinases IKK alpha, Active C51-10G Kinase Assay, Western Blot View IKK alpha, Active
siRNA Sets IKK beta siRNA Set I I03-911 View IKK beta siRNA Set I
Active Kinases IKK beta, Active I03-10BG Kinase Assay, Western Blot View IKK beta, Active
Active Kinases IKK beta, Active I03-18G Kinase Assay, Western Blot View IKK beta, Active
siRNA Sets IKK epsilon siRNA Set I I04-911 View IKK epsilon siRNA Set I
Active Kinases IKK epsilon, Active I04-10G Kinase Assay, Western Blot View IKK epsilon, Active
Cellular Proteins IKK gamma Protein I25-30G Western Blot View IKK gamma Protein
siRNA Sets IKKgamma siRNA Set I I25-911 View IKKgamma siRNA Set I
Peptide Substrates IKKtide I33-58 Kinase Assay View IKKtide
siRNA Sets IL-18 siRNA Set I I878-911 View IL-18 siRNA Set I
Growth Factors IL-2 I862-40N Cell Assay View IL-2
siRNA Sets IL-2 siRNA Set I I862-911 View IL-2 siRNA Set I
Growth Factors IL-8 (72AA) I868-40N Cell Assay View IL-8 (72AA)
siRNA Sets IL-8 (72AA) siRNA Set I I868-911 View IL-8 (72AA) siRNA Set I
siRNA Sets InsR siRNA Set I I08-911 View InsR siRNA Set I
Active Kinases InsR, Active I08-11G Kinase Assay, Western Blot View InsR, Active
Chemokines IP-10 I838-40N Cell Assay View IP-10
siRNA Sets IP-10 siRNA Set I I838-911 View IP-10 siRNA Set I
siRNA Sets IRR siRNA Set I I07-911 View IRR siRNA Set I
Active Kinases IRR, Active I07-11G Kinase Assay, Western Blot View IRR, Active
Cellular Proteins IRS1 (C-Term) Protein I40-31G Kinase Assay, Western Blot View IRS1 (C-Term) Protein
Cellular Proteins IRS1 (N-Term) Protein I40-35G Kinase Assay, Western Blot View IRS1 (N-Term) Protein
Peptide Substrates IRS1 (Y608) Peptide I40-58 Kinase Assay View IRS1 (Y608) Peptide
siRNA Sets IRS1 siRNA Set I I40-911 View IRS1 siRNA Set I
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Inhibitors K252A K10-900D View K252A
Kinase Inhibitors K252B K10-900E View K252B
siRNA Sets KDR siRNA Set I K01-911 View KDR siRNA Set I
Active Kinases KDR, Active K01-11G Kinase Assay, Western Blot View KDR, Active
Kinase Inhibitors Lapatinib E10-900D View Lapatinib
Growth Factors Leptin L833-40N Cell Assay View Leptin
siRNA Sets Leptin siRNA Set I L833-911 View Leptin siRNA Set I
Kinase Inhibitors Lestaurtinib F12-901 View Lestaurtinib
Kinase Inhibitors LY-294002 P27-900C View LY-294002
siRNA Sets LYN A siRNA Set I L13-911 View LYN A siRNA Set I
Active Kinases LYN A, Active L13-18G Kinase Assay, Western Blot View LYN A, Active
siRNA Sets LYN B siRNA Set I L13-911B View LYN B siRNA Set I
Active Kinases LYN B, Active L13-10G Kinase Assay, Western Blot View LYN B, Active
Kinase Inhibitors LYS6K2 R15-900 View LYS6K2
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cell Cycle Proteins MDM2 (1-118) Protein M45-31BH Western Blot View MDM2 (1-118) Protein
Cell Cycle Proteins MDM2 Protein M45-31G Western Blot View MDM2 Protein
siRNA Sets MDM2 siRNA Set I M45-911B View MDM2 siRNA Set I
Cell Cycle Proteins MDM4 (1-137) Protein M47-31BH Western Blot View MDM4 (1-137) Protein
siRNA Sets MDM4 siRNA Set I M47-911 View MDM4 siRNA Set I
Peptide Substrates Modified AKT Substrate A05-58B Kinase Assay View Modified AKT Substrate
Peptide Substrates Modified AKT Substrate II A05-58C Kinase Assay View Modified AKT Substrate II
Peptide Substrates Modified SGKtide S08-58B Kinase Assay View Modified SGKtide
siRNA Sets MST1 siRNA Set I S25-911 View MST1 siRNA Set I
Active Kinases MST1, Active S25-10G Kinase Assay, Western Blot View MST1, Active
siRNA Sets MST3 siRNA Set I S42-911 View MST3 siRNA Set I
Active Kinases MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
siRNA Sets MST4 siRNA Set I M59-911 View MST4 siRNA Set I
Active Kinases MST4, Active M59-10G Kinase Assay, Western Blot View MST4, Active
siRNA Sets mTOR siRNA Set I F17-911 View mTOR siRNA Set I
Transcription Proteins NFKB2 Protein N13-31G Western Blot View NFKB2 Protein
siRNA Sets NFKB2 siRNA Set I N13-911B View NFKB2 siRNA Set I
Active Kinase Mutants NPM1-ALK Mutant (F1174L), Active A19-19EG Kinase Assay View NPM1-ALK Mutant (F1174L), Active
Active Kinase Mutants NPM1-ALK Mutant, Active A19-19BG Kinase Assay View NPM1-ALK Mutant, Active
Kinase Inhibitors NVP-BEZ235 F17-900 View NVP-BEZ235
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
siRNA Sets p70S6K siRNA Set I R21-911 View p70S6K siRNA Set I
Active Kinases p70S6K, Active R21-10H Kinase Assay, Western Blot View p70S6K, Active
Unactive Kinases p70S6K, Unactive R21-14H Western Blot View p70S6K, Unactive
siRNA Sets p70S6Kb siRNA Set I R22-911 View p70S6Kb siRNA Set I
Active Kinases p70S6Kb, Active R22-10G Kinase Assay, Western Blot View p70S6Kb, Active
Unactive Kinases p70S6Kb, Unactive R22-14G Kinase Assay, Western Blot View p70S6Kb, Unactive
Kinase Protein p70S6KL1 Protein R25-34G Western Blot View p70S6KL1 Protein
siRNA Sets p70S6KL1 siRNA Set I R25-911 View p70S6KL1 siRNA Set I
Growth Factors PDGF P841-40N Cell Assay View PDGF
siRNA Sets PDGF siRNA Set I P841-911 View PDGF siRNA Set I
Active Kinase Mutants PDGFR alpha Mutant (D842V), Active P12-12BG Kinase Assay View PDGFR alpha Mutant (D842V), Active
Active Kinase Mutants PDGFR alpha Mutant (T674I), Active P12-12CG Kinase Assay View PDGFR alpha Mutant (T674I), Active
siRNA Sets PDGFR alpha siRNA Set I P12-911 View PDGFR alpha siRNA Set I
Active Kinases PDGFR alpha, Active P12-11G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR alpha, Active P12-18G Kinase Assay, Western Blot View PDGFR alpha, Active
siRNA Sets PDGFR beta siRNA Set I P13-911 View PDGFR beta siRNA Set I
Active Kinases PDGFR beta, Active P13-11G Kinase Assay, Western Blot View PDGFR beta, Active
siRNA Sets PDK1 siRNA Set I P14-911 View PDK1 siRNA Set I
Active Kinases PDK1, Active P14-10H Kinase Assay, Western Blot View PDK1, Active
Peptide Substrates PDKtide P10-58 Kinase Assay View PDKtide
Cellular Proteins PHLPP2 Protein P72-21G Phosphatase Assay, Western Blot View PHLPP2 Protein
siRNA Sets PHLPP2 siRNA Set I P72-911 View PHLPP2 siRNA Set I
Active Lipid Kinases PI3K (p110 alpha (E545K)/p85 alpha), Active P27-152H Kinase Assay View PI3K (p110 alpha (E545K)/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha (N345K)/p85 alpha), Active P27-122CH Kinase Assay View PI3K (p110 alpha (N345K)/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha(E542K)/p85) alpha, Active P27-122DH Kinase Assay View PI3K (p110 alpha(E542K)/p85) alpha, Active
siRNA Sets PI3K (p110 alpha) siRNA Set I P27-911 View PI3K (p110 alpha) siRNA Set I
Active Lipid Kinases PI3K (p110 alpha/p55 gamma), Active P27-102CH Kinase Assay View PI3K (p110 alpha/p55 gamma), Active
Active Kinases PI3K (p110 alpha/p55 gamma), Active P27-10CH Kinase Assay, Western Blot View PI3K (p110 alpha/p55 gamma), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-102G Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-102H Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-10G Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-10H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Active Lipid Kinases PI3K (p110 alpha/p85 alpha), Active P27-182H Kinase Assay View PI3K (p110 alpha/p85 alpha), Active
Active Kinases PI3K (p110 alpha/p85 alpha), Active P27-18H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
siRNA Sets PI3K (p110 beta) siRNA Set I P28-911 View PI3K (p110 beta) siRNA Set I
Active Lipid Kinases PI3K (p110 beta/p85 alpha), Active P28-102H Kinase Assay View PI3K (p110 beta/p85 alpha), Active
Active Kinases PI3K (p110 beta/p85 alpha), Active P28-10H Kinase Assay, Western Blot View PI3K (p110 beta/p85 alpha), Active
Active Lipid Kinases PI3K (p110 beta/p85 beta), Active P28-102BH Kinase Assay View PI3K (p110 beta/p85 beta), Active
Active Kinases PI3K (p110 beta/p85 beta), Active P28-10BH Kinase Assay, Western Blot View PI3K (p110 beta/p85 beta), Active
siRNA Sets PI3K (p110 delta) siRNA Set I P30-911 View PI3K (p110 delta) siRNA Set I
Active Lipid Kinases PI3K (p110 delta/p85 alpha), Active P30-102H Kinase Assay View PI3K (p110 delta/p85 alpha), Active
Active Kinases PI3K (p110 delta/p85 alpha), Active P30-10H Kinase Assay, Western Blot View PI3K (p110 delta/p85 alpha), Active
siRNA Sets PI3K (p120 gamma) siRNA Set I P29-911B View PI3K (p120 gamma) siRNA Set I
Active Lipid Kinases PI3K (p120 gamma), Active P29-102H Kinase Assay View PI3K (p120 gamma), Active
Active Kinases PI3K (p120 gamma), Active P29-10H Kinase Assay, Western Blot View PI3K (p120 gamma), Active
Cellular Proteins PI3K (p55 gamma) Protein P31-30CH Western Blot View PI3K (p55 gamma) Protein
siRNA Sets PI3K (p55 gamma) siRNA Set I P31-911B View PI3K (p55 gamma) siRNA Set I
Cellular Proteins PI3K (p65 alpha) Protein P31-31H Western Blot View PI3K (p65 alpha) Protein
Cellular Proteins PI3K (p85 alpha) Protein P31-30H Kinase Assay, Western Blot View PI3K (p85 alpha) Protein
siRNA Sets PI3K (p85 alpha) siRNA Set I P31-911C View PI3K (p85 alpha) siRNA Set I
Cellular Proteins PI3K (p85 beta) Protein P31-30BH Kinase Assay, Western Blot View PI3K (p85 beta) Protein
siRNA Sets PI3K (p85 beta) siRNA Set I P31-911D View PI3K (p85 beta) siRNA Set I
Active Kinase Mutants PI3K Mutant (p110 alpha(E542K)/p85 alpha), Active P27-12DH Kinase Assay, Western Blot View PI3K Mutant (p110 alpha(E542K)/p85 alpha), Active
Active Kinase Mutants PI3K Mutant (p110 alpha(E545K)/p85 alpha), Active P27-15H Kinase Assay View PI3K Mutant (p110 alpha(E545K)/p85 alpha), Active
Active Kinase Mutants PI3K Mutant (p110alpha(N345K)/p85alpha), Active P27-12CH Kinase Assay, Western Blot View PI3K Mutant (p110alpha(N345K)/p85alpha), Active
siRNA Sets PI4K2A siRNA Set I P21-911 View PI4K2A siRNA Set I
Active Lipid Kinases PI4K2A, Active P21-102G Kinase Assay View PI4K2A, Active
Active Kinases PI4K2A, Active P21-10G Kinase Assay, Western Blot View PI4K2A, Active
siRNA Sets PI4K2B siRNA Set I P22-911B View PI4K2B siRNA Set I
Active Lipid Kinases PI4K2B, Active P22-102G Kinase Assay View PI4K2B, Active
Active Kinases PI4K2B, Active P22-10G Kinase Assay, Western Blot View PI4K2B, Active
Kinase Protein PI4KA Protein P31-30G Western Blot View PI4KA Protein
siRNA Sets PI4KA siRNA Set I P31-911 View PI4KA siRNA Set I
Active Lipid Kinases PI4KA, Active P31-102G Kinase Assay View PI4KA, Active
siRNA Sets PI4KB siRNA Set I P32-911 View PI4KB siRNA Set I
Active Lipid Kinases PI4KB, Active P32-102G Kinase Assay View PI4KB, Active
Active Kinases PI4KB, Active P32-10G Kinase Assay, Western Blot View PI4KB, Active
Kinase Inhibitors Picropodophyllotoxin I02-901 View Picropodophyllotoxin
siRNA Sets PIK3C2A siRNA Set I P23-911 View PIK3C2A siRNA Set I
Active Lipid Kinases PIK3C2A, Active P23-112G Kinase Assay View PIK3C2A, Active
Active Kinases PIK3C2A, Active P23-11G Kinase Assay, Western Blot View PIK3C2A, Active
Kinase Protein PIK3C2B Protein P24-31BG Western Blot View PIK3C2B Protein
siRNA Sets PIK3C2B siRNA Set I P24-911 View PIK3C2B siRNA Set I
Active Lipid Kinases PIK3C2B, Active P24-112BG Kinase Assay View PIK3C2B, Active
siRNA Sets PIK3C2G siRNA Set I P25-911 View PIK3C2G siRNA Set I
Active Lipid Kinases PIK3C2G, Active P25-112G Kinase Assay View PIK3C2G, Active
Active Kinases PIK3C2G, Active P25-11G Kinase Assay, Western Blot View PIK3C2G, Active
siRNA Sets PIK3C3 (Vps34) siRNA Set I P26-911 View PIK3C3 (Vps34) siRNA Set I
Active Lipid Kinases PIK3C3 (Vps34), Active P26-102G Kinase Assay View PIK3C3 (Vps34), Active
Active Kinases PIK3C3 (Vps34), Active P26-10G Kinase Assay, Western Blot View PIK3C3 (Vps34), Active
siRNA Sets PIP4K2A siRNA Set I P76-911 View PIP4K2A siRNA Set I
Active Lipid Kinases PIP4K2A, Active P76-102AG Kinase Assay View PIP4K2A, Active
Active Kinases PIP4K2A, Active P76-10AG Kinase Assay, Western Blot View PIP4K2A, Active
Kinase Protein PIP4K2B Protein P76-30BG Western Blot View PIP4K2B Protein
siRNA Sets PIP4K2B siRNA Set I P76-911B View PIP4K2B siRNA Set I
Active Lipid Kinases PIP4K2B, Active P76-102BG Kinase Assay View PIP4K2B, Active
Kinase Protein PIP4K2C Protein P76-30CG Western Blot View PIP4K2C Protein
siRNA Sets PIP4K2C siRNA Set I P76-911C View PIP4K2C siRNA Set I
Active Lipid Kinases PIP4K2C, Active P76-102CG Kinase Assay View PIP4K2C, Active
siRNA Sets PIP5K1A siRNA Set I P16-911 View PIP5K1A siRNA Set I
Active Lipid Kinases PIP5K1A, Active P16-102AG Kinase Assay View PIP5K1A, Active
Active Kinases PIP5K1A, Active P16-10AG Kinase Assay, Western Blot View PIP5K1A, Active
siRNA Sets PIP5K1B siRNA Set I P16-911B View PIP5K1B siRNA Set I
Active Lipid Kinases PIP5K1B, Active P16-102BG Kinase Assay View PIP5K1B, Active
Active Kinases PIP5K1B, Active P16-10BG Kinase Assay, Western Blot View PIP5K1B, Active
siRNA Sets PIP5K1C siRNA Set I P16-911C View PIP5K1C siRNA Set I
Active Lipid Kinases PIP5K1C, Active P16-102CG Kinase Assay View PIP5K1C, Active
Active Kinases PIP5K1C, Active P16-10CG Kinase Assay, Western Blot View PIP5K1C, Active
Active Lipid Kinases PIP5K3 (PIKFYVE), Active P17-112BG Kinase Assay View PIP5K3 (PIKFYVE), Active
Active Kinases PIP5K3 (PIKFYVE), Active P17-11BG Kinase Assay, Western Blot View PIP5K3 (PIKFYVE), Active
Kinase Protein PIP5K3 Protein P17-31G Western Blot View PIP5K3 Protein
siRNA Sets PIP5K3 siRNA Set I P17-911 View PIP5K3 siRNA Set I
Kinase Inhibitors PKC-412 K10-900B View PKC-412
Active Phosphatases PP2A alpha/PPP2R1A Complex, Active P16-20BH Phosphatase Assay, Western Blot View PP2A alpha/PPP2R1A Complex, Active
Cellular Proteins PTEN Protein P23-34G Western Blot View PTEN Protein
siRNA Sets PTEN siRNA Set I P23-911B View PTEN siRNA Set I
Active Phosphatases PTEN, Active P23-20G Phosphatase Assay, Western Blot View PTEN, Active
Kinase Inhibitors PX-866 P27-900 View PX-866
Kinase Inhibitors Rapamycin F17-901 View Rapamycin
siRNA Sets REL A siRNA Set I R29-911 View REL A siRNA Set I
G-Proteins RGS1 Protein R39-30H Western Blot View RGS1 Protein
siRNA Sets RGS1 siRNA Set I R39-911 View RGS1 siRNA Set I
Kinase Protein RIOK1 Protein R04-34G Western Blot View RIOK1 Protein
Kinase Protein RIOK2 Protein R05-34G Western Blot View RIOK2 Protein
Kinase Protein RIOK3 Protein R06-34G Western Blot View RIOK3 Protein
siRNA Sets RON siRNA Set I M58-911 View RON siRNA Set I
Active Kinases RON, Active M58-11G Kinase Assay, Western Blot View RON, Active
siRNA Sets RSK4 siRNA Set I R20-911 View RSK4 siRNA Set I
Active Kinases RSK4, Active R20-10G Kinase Assay, Western Blot View RSK4, Active
Peptide Substrates S6K Substrate S05-58 Kinase Assay View S6K Substrate
Kinase Inhibitors SC-514 I03-901 View SC-514
Chemokines SDF-1 S821-40N Cell Assay View SDF-1
siRNA Sets SDF-1 siRNA Set I S821-911 View SDF-1 siRNA Set I
siRNA Sets SGK1 siRNA Set I S06-911 View SGK1 siRNA Set I
Active Kinases SGK1, Active S06-11G Kinase Assay, Western Blot View SGK1, Active
Unactive Kinases SGK1, Unactive S06-15G Kinase Assay, Western Blot View SGK1, Unactive
siRNA Sets SGK2 siRNA Set I S07-911 View SGK2 siRNA Set I
Active Kinases SGK2, Active S07-10G Kinase Assay, Western Blot View SGK2, Active
Unactive Kinases SGK2, Unactive S07-14G Kinase Assay, Western Blot View SGK2, Unactive
siRNA Sets SGK3 siRNA Set I S08-911 View SGK3 siRNA Set I
Active Kinases SGK3, Active S08-10G Kinase Assay, Western Blot View SGK3, Active
Unactive Kinases SGK3, Unactive S08-14G Kinase Assay, Western Blot View SGK3, Unactive
Kinase Protein SGK494 Protein S57-34G Kinase Assay View SGK494 Protein
Peptide Substrates SGKtide S08-58 Kinase Assay View SGKtide
Active Phosphatases SHIP1, Active P08-20G Phosphatase Assay, Western Blot View SHIP1, Active
Active Phosphatases SHIP2, Active P09-20G Phosphatase Assay, Western Blot View SHIP2, Active
Transcription Proteins SMAD1 Protein S10-30G Kinase Assay, Western Blot View SMAD1 Protein
siRNA Sets SMAD1 siRNA Set I S10-911 View SMAD1 siRNA Set I
Transcription Proteins SMAD2 (del SXS) Protein S11-31G Western Blot View SMAD2 (del SXS) Protein
Transcription Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
siRNA Sets SMAD2 siRNA Set I S11-911B View SMAD2 siRNA Set I
Transcription Proteins SMAD3 (del SXS) Protein S12-31G Western Blot View SMAD3 (del SXS) Protein
Transcription Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
siRNA Sets SMAD3 siRNA Set I S12-911B View SMAD3 siRNA Set I
Transcription Proteins SMAD4 Protein S13-30G Kinase Assay, Western Blot View SMAD4 Protein
siRNA Sets SMAD4 siRNA Set I S13-911 View SMAD4 siRNA Set I
Transcription Proteins SMAD5 Protein S14-30G Kinase Assay, Western Blot View SMAD5 Protein
siRNA Sets SMAD5 siRNA Set I S14-911B View SMAD5 siRNA Set I
Transcription Proteins SMAD9 Protein S17-30G Western Blot View SMAD9 Protein
siRNA Sets SMAD9 siRNA Set I S17-911 View SMAD9 siRNA Set I
Kinase Inhibitors Staurosporine K10-900 View Staurosporine
siRNA Sets STK3 siRNA Set I S24-911 View STK3 siRNA Set I
Active Kinases STK3, Active S24-10G Kinase Assay, Western Blot View STK3, Active
Kinase Inhibitors Sunitinib malate F11-900G View Sunitinib malate
siRNA Sets SYK siRNA Set I S52-911B View SYK siRNA Set I
Active Kinases SYK, Active S52-10G Kinase Assay, Western Blot View SYK, Active
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
siRNA Sets TAB1 siRNA Set I T01-911 View TAB1 siRNA Set I
siRNA Sets TAK1 siRNA Set I M15-911 View TAK1 siRNA Set I
Active Kinases TAK1-TAB1, Active M15-13G Kinase Assay, Western Blot View TAK1-TAB1, Active
Active Kinase Mutants TFG-ALK Mutant, Active A19-19CG Kinase Assay View TFG-ALK Mutant, Active
Active Kinase Mutants TFG-TRKA Mutant (TRK-T3), Active N16-19CG Kinase Assay View TFG-TRKA Mutant (TRK-T3), Active
Growth Factors TGFB1 T831-40N Cell Assay View TGFB1
siRNA Sets TGFB1 siRNA Set I T831-911 View TGFB1 siRNA Set I
Growth Factors TGFB3 T833-40CN Cell Assay View TGFB3
siRNA Sets TGFB3 siRNA Set I T833-911 View TGFB3 siRNA Set I
Active Kinases TGFBR1 (ALK5), Active T07-11BG Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Active Kinases TGFBR1 (ALK5), Active T07-11G Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Active Kinase Mutants TGFBR1 Mutant (T204D), Active T07-13G Kinase Assay View TGFBR1 Mutant (T204D), Active
Peptide Substrates TGFBR1 Peptide T36-58 Peptide Substrate View TGFBR1 Peptide
siRNA Sets TGFBR1 siRNA Set I T07-911B View TGFBR1 siRNA Set I
Unactive Kinases TGFBR1, Unactive T07-35G Kinase Assay, Western Blot View TGFBR1, Unactive
siRNA Sets TGFBR2 siRNA Set I T08-911B View TGFBR2 siRNA Set I
Active Kinases TGFBR2, Active T08-11BG Kinase Assay, Western Blot View TGFBR2, Active
Active Kinases TGFBR2, Active T08-11G Kinase Assay, Western Blot View TGFBR2, Active
Cytokines TNF-alpha T860-40N Cell Assay View TNF-alpha
siRNA Sets TNF-alpha siRNA Set I T860-911 View TNF-alpha siRNA Set I
Cytokines TNFB T861-40N Cell Assay View TNFB
siRNA Sets TNFB siRNA Set I T861-911 View TNFB siRNA Set I
Adaptor Proteins TRAF1 Protein T56-30G Western Blot View TRAF1 Protein
Adaptor Proteins TRAF2 Protein T57-30G Western Blot View TRAF2 Protein
siRNA Sets TRAF2 siRNA Set I T57-911 View TRAF2 siRNA Set I
siRNA Sets TRAF3 siRNA Set I T58-911 View TRAF3 siRNA Set I
Cytokines TRAIL T880-40N Cell Assay View TRAIL
siRNA Sets TRAIL siRNA Set I T880-911 View TRAIL siRNA Set I
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Inhibitors Wortmannin P27-900B View Wortmannin
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein New Research Category Y71-30BH Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30G Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein New Research Category Y71-30H Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30N Western Blot View 14-3-3 alpha/beta Protein
siRNA Sets 14-3-3 alpha/beta siRNA Set I Y71-911 View 14-3-3 alpha/beta siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein New Research Category Y75-30BH Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein New Research Category Y75-30H Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30N Western Blot View 14-3-3 epsilon Protein
siRNA Sets 14-3-3 epsilon siRNA Set I Y75-911 View 14-3-3 epsilon siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30BH Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30H Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein New Research Category Y76-30N Western Blot View 14-3-3 eta Protein
Cell Stress & Chaperone Proteins 14-3-3 eta Protein (C-term GST) New Research Category Y76-30CG Western Blot View 14-3-3 eta Protein (C-term GST)
Cell Stress & Chaperone Proteins 14-3-3 eta Protein (N-term GST) New Research Category Y76-30G Western Blot View 14-3-3 eta Protein (N-term GST)
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30BH Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30H Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein New Research Category Y77-30N Western Blot View 14-3-3 gamma Protein
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein (C-term GST) New Research Category Y77-30CG Western Blot View 14-3-3 gamma Protein (C-term GST)
Cell Stress & Chaperone Proteins 14-3-3 gamma Protein (N-term GST) New Research Category Y77-30G Western Blot View 14-3-3 gamma Protein (N-term GST)
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30G Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein New Research Category Y86-30H Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30N Western Blot View 14-3-3 sigma Protein
siRNA Sets 14-3-3 sigma siRNA Set I Y86-911 View 14-3-3 sigma siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 theta Protein New Research Category Y84-30BH Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein New Research Category Y84-30H Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
siRNA Sets 14-3-3 theta siRNA Set I Y84-911 View 14-3-3 theta siRNA Set I
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein New Research Category Y92-30BH Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30G Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein New Research Category Y92-30H Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30N Western Blot View 14-3-3 zeta Protein
siRNA Sets 14-3-3 zeta siRNA Set I Y92-911 View 14-3-3 zeta siRNA Set I
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cellular Proteins 4EBP1 Protein E35-54BH Kinase Assay, Western Blot View 4EBP1 Protein
Cellular Proteins 4EBP1 Protein E35-54G Kinase Assay, Western Blot View 4EBP1 Protein
Cellular Proteins 4EBP1 Protein E35-54H Western Blot View 4EBP1 Protein
siRNA Sets 4EBP1 siRNA Set I E35-911 View 4EBP1 siRNA Set I
Kinase Inhibitors 6BIO G08-900 View 6BIO
AKT/PKB Pathway Product Listing Found: Total 593 Products Matching Research Category AKT/PKB Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Kinase Activators 8-pCPT-2-O-Me-cAMP-AM R46-905 View 8-pCPT-2-O-Me-cAMP-AM
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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active GTPases/ATPases Active GTPases/ATPases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinase Mutants Active Kinase Mutants
Enzymes Active Kinases Active Kinases
Enzymes Active Lipid Kinases Active Lipid Kinases
Enzymes Active Methyltransferases Active Methyltransferases
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Enzymes Active Proteases Active Proteases
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Biochemical Compounds
Biochemical Compounds Epigenetic Enzyme Activators Epigenetic Enzyme Activators
Biochemical Compounds Epigenetic Enzyme Inhibitors Epigenetic Enzyme Inhibitors
Biochemical Compounds Kinase Activators Kinase Activators
Biochemical Compounds Kinase Inhibitors Kinase Inhibitors
Biochemical Compounds Phosphatase Inhibitors Phosphatase Inhibitors
Biochemical Compounds siRNA Controls siRNA Controls
Biochemical Compounds siRNA Sets siRNA Sets
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferases Acetyl/Methyltransferases
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylases Deacetylase/Demethylases
Signaling Proteins Dihydropyrimidinase Dihydropyrimidinase
Signaling Proteins Dioxygenases Dioxygenases
Signaling Proteins Fructose Kinases Fructose Kinases
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Kinase Mutant Proteins Kinase Mutant Proteins
Signaling Proteins Kinase Protein Kinase Protein
Signaling Proteins Lysyl Oxidases Lysyl Oxidases
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Phospholipase C Proteins Phospholipase C Proteins
Signaling Proteins Superoxide Dismutase Superoxide Dismutase
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Lipid Substrates Lipid Substrates
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Fa