MEK2 Active Enzymes Active Kinases


Home › Enzymes - Active Kinases › MEK2, Active

MEK2, Active (M03-10G)
Catalog Number Pack Size Price (USD)  
MEK2, Active M03-10G-05 5 ug $205   MEK2, Active Add to Cart
MEK2, Active M03-10G-10 10 ug $295   MEK2, Active Add to Cart
MEK2, Active M03-10G-BULK BULK CONTACT US  
* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.

Bulk Pricing for MEK2, Active

Product Data Sheet(s)




Description: Recombinant full-length human MEK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_030662
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~71 kDa

Gene Aliases: MAP2K2, MKK2, PRKMK2, MAPKK2

Scientific Background: MEK2 is the member of MAPK kinase (MAPKK) family of signaling protein kinases. MEK2 is a dual-specificity kinase that activates the extracellular signal-regulated kinase (ERK) and mitogen-activated protein (MAP) kinase upon agonist binding to receptors. MEK2 plays a key role in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathways (1). Approximately 30% of all human cancers have a constitutively activated MAPK pathway, and constitutive activation of MEK2 results in cellular transformation. The ERK/MAP kinase cascade regulates cell growth and differentiation (2).

References: 
1. Shuichan, Xu et al: Differential Regulation of Mitogen-Activated Protein/ERK Kinase (MEK)1 and MEK2 and Activation by a Ras-Independent Mechanism. Mol. Endocrinol. 1997;11 (11): 1618-1625.

2. Louis-François, B, et al: Mek2 Is Dispensable for Mouse Growth and Development. Mol. Cellular Biol. 2003; 23 (14): 4778-4787.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




MEK2, Active Research Areas

The MEK2, Active product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases



MEK2, Active Related Products Found: Total 34 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Signaling Proteins ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Enzymes HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
Signaling Proteins RAS Protein R05-30G Kinase Assay, Western Blot View RAS Protein
Enzymes MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Enzymes MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Enzymes AMPK (A1/B1/G1), Active P47-10H Kinase Assay, Western Blot View AMPK (A1/B1/G1), Active
Enzymes BRAF, Active B08-11G Kinase Assay, Western Blot View BRAF, Active
Enzymes COT, Active M16-11G Kinase Assay, Western Blot View COT, Active
Enzymes MINK1, Active M53-11G Kinase Assay, Western Blot View MINK1, Active
Enzymes RAF1 (EE), Active R01-13G Kinase Assay, Western Blot View RAF1 (EE), Active
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Signaling Reagents MBP Protein M42-54G Kinase Assay, Western Blot View MBP Protein
Enzymes AMPK (A2/B1/G1), Active P48-10H Kinase Assay, Western Blot View AMPK (A2/B1/G1), Active
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Enzymes AMPK (A1/B1/G2), Active P55-10H Kinase Assay, Western Blot View AMPK (A1/B1/G2), Active
Enzymes MEK1, Active M02-10G Kinase Assay, Western Blot View MEK1, Active
Enzymes HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Signaling Proteins COT, Unactive M16-15G Kinase Assay, Western Blot View COT, Unactive
Enzymes BRAF (V599E), Active B08-13G Kinase Assay, Western Blot View BRAF (V599E), Active
Signaling Proteins ELK1 Protein E64-30G Kinase Assay, Western Blot View ELK1 Protein
Signaling Reagents ATP Stock Solution A50-09 Kinase Assay View ATP Stock Solution
Signaling Reagents Kinase Dilution Buffer III K23-09 Kinase Assay View Kinase Dilution Buffer III
Signaling Proteins MEK1, Unactive M02-14H Kinase Assay, Western Blot View MEK1, Unactive
Enzymes AMPK (A1/B1/G3), Active P56-10H Kinase Assay, Western Blot View AMPK (A1/B1/G3), Active
Enzymes AMPK (A1/B2/G1), Active P50-10H Kinase Assay, Western Blot View AMPK (A1/B2/G1), Active
Enzymes MEKK2, Active M10-10G Kinase Assay, Western Blot View MEKK2, Active
Enzymes MEKK3, Active M11-10G Kinase Assay, Western Blot View MEKK3, Active
Enzymes TOPK, Active T14-10G Kinase Assay, Western Blot View TOPK, Active
Antibodies Anti-MEK2 M03-63R WB View Anti-MEK2
Antibodies Anti-MEK1/2 M02-63R WB View Anti-MEK1/2
Signaling Reagents ERK1 (K71A) Protein M29-16H Kinase Assay, Western Blot View ERK1 (K71A) Protein


Items in Your Cart (0)
Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




Keep in touch, join us on:
MEK2, Active Enzymes Active Kinases    MEK2, Active Enzymes Active Kinases    MEK2, Active Enzymes Active Kinases