PP2Abeta Protein Cell Signaling Reagents Cellular Proteins


Home › Cell Signaling Reagents - Cellular Proteins › PP2Abeta Protein

PP2Abeta Protein (P17-34G)
Catalog Number Pack Size Price (USD)  
PP2Abeta Protein P17-34G-20 20 ug $195 PP2Abeta Protein  40% OFF   PP2Abeta Protein Add to Cart
PP2Abeta Protein P17-34G-50 50 ug $395 PP2Abeta Protein  40% OFF   PP2Abeta Protein Add to Cart
PP2Abeta Protein P17-34G-BULK BULK CONTACT US  
* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.

Bulk Pricing for PP2Abeta Protein

Product Data Sheet(s)




Description: Recombinant full-length human PP2Abeta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_004156
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Western Blot

Molecular Weight: ~59 kDa

Gene Aliases: PP2A-beta, PP2CB; PPP2CB

Scientific Background: PP2A is one of the four major Ser/Thr phosphatases which are implicated in the negative control of cell growth and division and encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A (1). PP2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B which is encoded by a diverse set of genes. The interaction was independent of ATP or magnesium ion and the inclusion of PTPA altered the substrate specificity of PP2A, with enhanced phosphotyrosine phosphatase activity and decreased phosphoserine phosphatase activity (2).

References: 
1. Van Hoof, C. et.al: Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A. Genomics 28: 261-272, 1995.

2. Chao, Y. et.al: Structure and mechanism of the phosphotyrosyl phosphatase activator. Molec. Cell 23: 535-546, 2006.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




PP2Abeta Protein Research Areas

The PP2Abeta Protein product can be utilized in the following research areas, but not limited to:

Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Metabolic Disorder, Phosphatases, Ser/Thr Kinases



PP2Abeta Protein Related Products Found: Total 6 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes PP1A, Active P13-20G Phosphatase Assay, Western Blot View PP1A, Active
Enzymes PP1B, Active P14-20G Phosphatase Assay, Western Blot View PP1B, Active
Enzymes PP2Aalpha, Active P16-20G Phosphatase Assay, Western Blot View PP2Aalpha, Active
Enzymes PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
Enzymes PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
Signaling Proteins PP2B Protein P18-34G Western Blot View PP2B Protein


Items in Your Cart (0)
Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




Keep in touch, join us on:
PP2Abeta Protein Cell Signaling Reagents Cellular Proteins    PP2Abeta Protein Cell Signaling Reagents Cellular Proteins    PP2Abeta Protein Cell Signaling Reagents Cellular Proteins