p38 beta Active Enzymes Active Kinases


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p38 beta, Active (M36-10BG)
Catalog Number Pack Size Price (USD)  
p38 beta, Active M36-10BG-05 5 ug $205   p38 beta, Active Add to Cart
p38 beta, Active M36-10BG-10 10 ug $295   p38 beta, Active Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human p38β was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_002751
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~71 kDa

Gene Aliases: MAPK11; SAPK2; p38-2; PRKM11; SAPK2B; p38b; P38b2

Scientific Background: p38β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38β is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.

References: 
1. Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38-beta). J. Biol. Chem. 271: 17920-17926, 1996.

2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509-19517, 1997.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




p38 beta, Active Research Areas

The p38 beta, Active product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases



p38 beta, Active Related Products Found: Total 14 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes p38 alpha, Active M39-10BG Kinase Assay, Western Blot View p38 alpha, Active
Enzymes p38 delta, Active M38-10BG Kinase Assay, Western Blot View p38 delta, Active
Enzymes p38 gamma, Active M37-10BG Kinase Assay, Western Blot View p38 gamma, Active
Signaling Proteins p38 alpha, Unactive M39-14G Kinase Assay, Western Blot View p38 alpha, Unactive
Signaling Proteins p38 beta, Unactive M36-14G Kinase Assay, Western Blot View p38 beta, Unactive
Signaling Proteins p38 alpha, Unactive M39-14U Kinase Assay, Western Blot View p38 alpha, Unactive
Signaling Proteins p38 delta, Unactive M38-14G Kinase Assay, Western Blot View p38 delta, Unactive
Signaling Proteins p38 gamma, Unactive M37-14G Kinase Assay, Western Blot View p38 gamma, Unactive
Antibodies Anti-p38 alpha M39-60M WB View Anti-p38 alpha
Antibodies Anti-p38 alpha M39-63R WB View Anti-p38 alpha
Antibodies Anti-p38 beta M36-63R WB View Anti-p38 beta
Antibodies Anti-p38 gamma M37-63R WB View Anti-p38 gamma
Signaling Reagents p38 Substrate P03-58 Kinase Assay View p38 Substrate
Signaling Reagents p38 alpha (K53A), Unactive M39-16H Kinase Assay, Western Blot View p38 alpha (K53A), Unactive


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Product Types
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Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
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Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
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Signaling Reagents
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Antibodies
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Discovery Services
Compound Selective Profiling Compound Selective Profiling
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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