FGR Active Enzymes Active Kinases


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FGR, Active (F10-10G)
Catalog Number Pack Size Price (USD)  
FGR, Active F10-10G-05 5 ug $205   FGR, Active Add to Cart
FGR, Active F10-10G-10 10 ug $295   FGR, Active Add to Cart
FGR, Active F10-10G-BULK BULK CONTACT US  
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Bulk Pricing for FGR, Active

Product Data Sheet(s)




Description: Recombinant full-length human FGR was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_005248
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~86kDa

Gene Aliases : SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr

Scientific Background: FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (1). FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell (2).

References: 
1. Cheah, MS. et al: fgr proto-oncogene mRNA induced in B lymphocytes by Epstein-Barr virus infection. Nature. 1986 Jan 16-22;319(6050):238-40..

2. Willman, CL. et al: Differential expression and regulation of the c-src and c-fgr protooncogenes in myelomonocytic cells. Proc Natl Acad Sci U S A. 1987 Jul;84(13):4480-4..



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




FGR, Active Research Areas

The FGR, Active product can be utilized in the following research areas, but not limited to:

Angiogenesis, Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation



FGR, Active Related Products Found: Total 18 Related Products
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Enzymes SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Enzymes LCK, Active L03-10G Kinase Assay, Western Blot View LCK, Active
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Enzymes FRK, Active F14-11G Kinase Assay, Western Blot View FRK, Active
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Enzymes LYN A, Active L13-18G Kinase Assay, Western Blot View LYN A, Active
Signaling Proteins FYN C, Unactive F15-14G Kinase Assay, Western Blot View FYN C, Unactive
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Signaling Proteins PTEN Protein P23-34G Western Blot View PTEN Protein
Signaling Reagents Poly (4:1 Glu, Tyr) Peptide P61-58 Kinase Assay View Poly (4:1 Glu, Tyr) Peptide
Enzymes YES1, Active Y01-10G Kinase Assay, Western Blot View YES1, Active


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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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