FYN C Unactive Cell Signaling Reagents Unactive Kinases


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FYN C, Unactive (F15-14G)
Catalog Number Pack Size Price (USD)  
FYN C, Unactive F15-14G-20 20 ug $195 FYN C, Unactive  40% OFF   FYN C, Unactive Add to Cart
FYN C, Unactive F15-14G-50 50 ug $395 FYN C, Unactive  40% OFF   FYN C, Unactive Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human FYN C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: BC032496
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~80kDa

Gene Aliases : SLK, SYN, MGC45350

Scientific Background: Fyn C (Fyn isoform C) is a member of the SRC tyrosine kinase oncogene family showing high homology to YES1, FGR and SRC. Fyn is a membrane-associated tyrosine kinase involved in the control of cell growth and can interact with Fyn-binding protein and the p85 subunit of PI3K (1). Fyn has been shown to be part of a protein complex involving DCC and FAK which is downstream of Netrin-1, a pathway important in promoting both axonal outgrowth and axonal guidance in path finding (2).

References: 
1. Semba, K. et al: yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family. Proc. Nat. Acad. Sci. 83: 5459-5463, 1986.

2. Li, W. et al: Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nature Neurosci. 7: 1213-1221, 2004.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




FYN C, Unactive Research Areas

The FYN C, Unactive product can be utilized in the following research areas, but not limited to:

Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Neurobiology



FYN C, Unactive Related Products Found: Total 11 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Enzymes SRC, Active S19-18G Kinase Assay, Western Blot View SRC, Active
Signaling Reagents SRC Substrate S30-58 Kinase Assay View SRC Substrate
Enzymes LCK, Active L03-10G Kinase Assay, Western Blot View LCK, Active
Enzymes ZAP70, Active Z02-10G Kinase Assay, Western Blot View ZAP70, Active
Enzymes LYN A, Active L13-18G Kinase Assay, Western Blot View LYN A, Active
Enzymes LYN B, Active L13-10G Kinase Assay, Western Blot View LYN B, Active
Enzymes FGR, Active F10-10G Kinase Assay, Western Blot View FGR, Active
Enzymes FYN A, Active F15-10G Kinase Assay, Western Blot View FYN A, Active
Enzymes SLK, Active S11-10G Kinase Assay, Western Blot View SLK, Active
Enzymes YES1, Active Y01-10G Kinase Assay, Western Blot View YES1, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
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Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
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Signaling Proteins G-Proteins G-Proteins
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Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
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Signaling Reagents
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Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
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Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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