CAMK1 Active Enzymes Active Kinases


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CAMK1, Active (C07-10G)
Catalog Number Pack Size Price (USD)  
CAMK1, Active C07-10G-05 5 ug $205   CAMK1, Active Add to Cart
CAMK1, Active C07-10G-10 10 ug $295   CAMK1, Active Add to Cart
CAMK1, Active C07-10G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length mouse CAMK1 was expressed in E. coli cells using an N-terminal GST tag.
Tag: GST tag
Expression System: E.coli
Species: Mouse
Sequence: Full length
Genbank Number: NM_133926
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~70 kDa

Gene Aliases : AI505105; D6Ertd263e

Scientific Background: CAMK1 is a serine/threonine protein kinase that is a member of the multifunctional calcium/calmodulin-dependent protein kinase family. CAMK1 is ubiquitously expressed and phosphorylates a number of proteins including SYN1, SYN2, CREB and CFTR. In addition, Numb family of proteins may also be intracellular targets for CAMK1, and they may also be regulated by phosphorylation-dependent interaction with 14-3-3 protein (1). CAMK1 also plays an important role in the trafficking of HDAC7 between the cytoplasm and the nucleus. CAMK1 phosphorylates HDAC7 on multiple sites that lead to alteration in localization of HDAC7 (2).

References: 
1. Tokumitsu, H. et al: Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases. J Biol Chem. 2005 Oct 21;280(42):35108-18.

2. Gao, C. et al: CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s. FEBS Lett. 2006 Sep 18;580(21):5096-104.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




CAMK1, Active Research Areas

The CAMK1, Active product can be utilized in the following research areas, but not limited to:

Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases



CAMK1, Active Related Products Found: Total 18 Related Products
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Enzymes CAMK2 alpha, Active C11-10G Kinase Assay, Western Blot View CAMK2 alpha, Active
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Signaling Reagents CREBtide C50-58 Kinase Assay View CREBtide
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Antibodies Anti-CAMK1 C07-60M WB View Anti-CAMK1
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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
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Extracellular Ligands Cytokines Cytokines
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Signaling Proteins
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Signaling Proteins Arginine Deiminases Arginine Deiminases
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Discovery Services
Compound Selective Profiling Compound Selective Profiling
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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