STAT3 Protein Cell Signaling Reagents Transcription Proteins


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STAT3 Protein (S54-54G)
Catalog Number Pack Size Price (USD)  
STAT3 Protein S54-54G-20 20 ug $195 STAT3 Protein  40% OFF   STAT3 Protein Add to Cart
STAT3 Protein S54-54G-50 50 ug $395 STAT3 Protein  40% OFF   STAT3 Protein Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human STAT3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_139276
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~120 kDa

Gene Aliases: APRF, FLJ20882, MGC16063

Scientific Background: STAT3 is a member of the signal transducers and activators of transcription (STAT) family of proteins that carry out a dual function: signal transduction and activation of transcription. STAT3 is widely expressed and becomes activated through phosphorylation on tyrosine as a DNA binding protein in response to a variety of stimuli such as EGF, IL-6, PDGF, IL-2 and G-CSF (1). This phosphoprotein forms homodimers as well as heterodimers with other members of the STAT family and translocate to the nucleus in order to modulate the transcription of various genes (2).

References: 
1. Zhong, Z. et al: Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science. 1994 Apr 1;264(5155):95-8.

2. Tian, S. S. et al: Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood. 1994 Sep 15;84(6):1760



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




STAT3 Protein Research Areas

The STAT3 Protein product can be utilized in the following research areas, but not limited to:

Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway



STAT3 Protein Related Products Found: Total 20 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Signaling Proteins STAT1 beta Protein S52-54G Kinase Assay, Western Blot View STAT1 beta Protein
Signaling Proteins STAT2 Protein S53-54G Kinase Assay, Western Blot View STAT2 Protein
Enzymes SRC, Active S19-18G Kinase Assay, Western Blot View SRC, Active
Enzymes AMPK (A1/B1/G1), Active P47-10H Kinase Assay, Western Blot View AMPK (A1/B1/G1), Active
Enzymes AMPK (A2/B1/G1), Active P48-10H Kinase Assay, Western Blot View AMPK (A2/B1/G1), Active
Enzymes AMPK (A1/B1/G2), Active P55-10H Kinase Assay, Western Blot View AMPK (A1/B1/G2), Active
Enzymes AMPK (A1/B1/G3), Active P56-10H Kinase Assay, Western Blot View AMPK (A1/B1/G3), Active
Enzymes AMPK (A1/B2/G1), Active P50-10H Kinase Assay, Western Blot View AMPK (A1/B2/G1), Active
Signaling Proteins STAT3 Protein S54-54H Kinase Assay, Western Blot View STAT3 Protein
Signaling Proteins STAT4 Protein S55-54H Kinase Assay, Western Blot View STAT4 Protein
Signaling Proteins STAT5 Protein S56-54H Kinase Assay, Western Blot View STAT5 Protein
Signaling Proteins SMAD1 Protein S10-30G Kinase Assay, Western Blot View SMAD1 Protein
Enzymes JAK2, Active J02-11H Kinase Assay, Western Blot View JAK2, Active
Antibodies Anti-STAT5 S56-63R WB View Anti-STAT5
Antibodies Anti-STAT3 S54-63R WB View Anti-STAT3
Antibodies Anti-STAT1 beta S52-63R WB View Anti-STAT1 beta
Antibodies Anti-STAT4 S55-63R WB View Anti-STAT4
Signaling Proteins STAT6 Protein S57-30G Kinase Assay, Western Blot View STAT6 Protein
Signaling Proteins STAT1 alpha Protein S52-50G Western Blot View STAT1 alpha Protein


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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