ERK/MAPK Pathway


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ERK/MAPK Pathway

The ERK pathway incorporates multiple signaling proteins including Ras, c-Raf, MEK1/2, ERK1/2 (ERKs), RSK 1/2/3 and transcription factors such as Elk and Ets (1). The ERK family members become activated via phosphorylation on tyrosine and threonine residues in response to mitogens and other stimuli by the MAP/ERK Kinases or MEKs (ERKs also have the capacity to autophosphorylate on these amino acid residues).


ERKs respond to mitogenic signals by phosphorylating multiple down-stream components which include transcription factors, protein kinases and phosphatases, cytoskeletal elements, regulators of apoptosis and a variety of other signaling-related molecules (2). Many of these substrates are localized in the nucleus, and participate in the regulation of transcription upon stimulation while other substrates are found in the cytosol and organelles. Transforming agents utilize the ERK/MAPK pathway in inducing cell proliferation. The ERK pathway is often up-regulated in many human tumors and as such represents an attractive target for the development of anticancer drugs (3). For instance, activating mutations in either B-Raf or N-Ras leads to the activation of the ERK/MAPK pathway in most cutaneous melanomas (4). Inhibition of the ERK/MAPK pathway results in the dephosphorylation of the proapoptotic Bcl-2 family members Bad and Bim which lead to caspase activation and, ultimately, the demise of melanoma cells through the induction of apoptosis.


Because of its multiple roles in the acquisition of a complex malignant phenotype, specific blockade of the ERK pathway is expected to result in not only an anti-proliferative effect but also in anti-metastatic and antiangiogenic effects in tumor cells. Recently potent small-molecule inhibitors targeting the components of the ERK pathway have been developed, some of which have reached the clinical trial stage (5).


REFERENCES
1. Rubinfeld, H. et al: The ERK cascade: A prototype of MAPK signaling. Mol Biotechnol. 2005 Oct;31(2):151-74.
2. Yoon, S. et al: The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions. Growth Factors. 2006 Mar;24(1):21-44.
3. Reddy, K. B. et al: Role of MAP kinase in tumor progression and invasion. Cancer Metastasis Rev. 2003 Dec;22(4):395-403.
4. Panka, D. J. et al: Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma. Clin Cancer Res. 2006 Apr 1;12(7 Pt 2):2371s-2375s.
5. Kohno, M. et al: Targeting the ERK signaling pathway in cancer therapy. Ann Med. 2006;38(3):200-11.


ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30G Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30N Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30N Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30G Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30N Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30G Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30N Western Blot View 14-3-3 zeta Protein
Peptide Substrates Acetylated Histone H3 Peptide I H12-358 Acetylation/Methylation Assays View Acetylated Histone H3 Peptide I
Peptide Substrates Acetylated Histone H4 Peptide I H13-358 Acetylation/Methylation Assays View Acetylated Histone H4 Peptide I
Assay Reagents Acetyltransferase Assay Buffer A01-09 Acetyltransferase Assay View Acetyltransferase Assay Buffer
Assay Reagents Acetyltransferase Dilution Buffer A21-09 Acetyltransferase Assay View Acetyltransferase Dilution Buffer
Active Kinases ACK, Active A05-11G Kinase Assay, Western Blot View ACK, Active
Primary Antibodies Anti-ASK1 M13-60BM WB View Anti-ASK1
Primary Antibodies Anti-ASK1 M13-60M WB View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63BR WB, ELISA, ICC, IF View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63CR WB, ELISA View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63R WB, ELISA, ICC, IF View Anti-ASK1
Primary Antibodies Anti-BRAF New Research Category B08-63R WB, ELISA View Anti-BRAF
Isoform Specific Antibodies Anti-CAMK1 C07-60M WB View Anti-CAMK1
Primary Antibodies Anti-CASK New Research Category C19-63R WB, ELISA, IF View Anti-CASK
Primary Antibodies Anti-CDC25A C04-63R WB View Anti-CDC25A
Primary Antibodies Anti-CDC42 New Research Category C08-363R WB, ELISA View Anti-CDC42
Primary Antibodies Anti-CREB C49-63R WB, IP View Anti-CREB
Primary Antibodies Anti-DLK1 New Research Category M20-63R WB, ELISA View Anti-DLK1
Primary Antibodies Anti-DOK1 D42-63R WB View Anti-DOK1
Primary Antibodies Anti-EGFR E10-63BR WB View Anti-EGFR
Primary Antibodies Anti-EGFR E10-63R WB View Anti-EGFR
Primary Antibodies Anti-eIF4E E34-63R WB View Anti-eIF4E
Primary Antibodies Anti-ELK1 E64-63R WB View Anti-ELK1
Isoform Specific Antibodies Anti-ERK1 M29-60BM WB, IP View Anti-ERK1
Primary Antibodies Anti-ERK1 M29-60CM IP View Anti-ERK1
Isoform Specific Antibodies Anti-ERK1 M29-60M WB, IP View Anti-ERK1
Primary Antibodies Anti-ERK1/2 M29-60EM WB View Anti-ERK1/2
Primary Antibodies Anti-ERK2 M28-63R WB View Anti-ERK2
Primary Antibodies Anti-FLT3 New Research Category F12-63R WB, ELISA, IF View Anti-FLT3
Primary Antibodies Anti-GAB1 G03-63R WB View Anti-GAB1
Primary Antibodies Anti-IRS1 New Research Category I40-363R WB, ELISA, ICC, IF View Anti-IRS1
Isoform Specific Antibodies Anti-MEK1 M02-60M WB, IP View Anti-MEK1
Primary Antibodies Anti-MEK1/2 M02-63R WB View Anti-MEK1/2
Isoform Specific Antibodies Anti-MEK2 M03-63R WB View Anti-MEK2
Primary Antibodies Anti-NIK New Research Category N22-63R WB, ELISA View Anti-NIK
Isoform Specific Antibodies Anti-PAK1 P02-63R WB View Anti-PAK1
Primary Antibodies Anti-PAK2 New Research Category P03-63BR WB, ELISA, IF, IHC View Anti-PAK2
Primary Antibodies Anti-PAK2 New Research Category P03-63R WB, ELISA, IF, IHC View Anti-PAK2
Primary Antibodies Anti-PAK4 New Research Category P05-163R WB, ELISA, ICC, IF View Anti-PAK4
Primary Antibodies Anti-PAK6 New Research Category P06-63R WB, ELISA, IF, IHC View Anti-PAK6
Primary Antibodies Anti-PAK7 New Research Category P07-63R WB, ELISA, ICC, IF View Anti-PAK7
Primary Antibodies Anti-PDFGB New Research Category P842-63R WB, ELISA View Anti-PDFGB
Modification Antibodies Anti-Phosphoserine (Anti-pS) S95-65R WB, ELISA, IP, IHC View Anti-Phosphoserine (Anti-pS)
Modification Antibodies Anti-Phosphoserine (Anti-pS), Biotin Conjugated S95-65BR WB, ELISA View Anti-Phosphoserine (Anti-pS), Biotin Conjugated
Modification Antibodies Anti-Phosphothreonine (Anti-pT) T95-65R WB, ELISA, IP, IHC View Anti-Phosphothreonine (Anti-pT)
Modification Antibodies Anti-Phosphothreonine (Anti-pT), Biotin Conjugated T95-65BR WB, ELISA View Anti-Phosphothreonine (Anti-pT), Biotin Conjugated
Modification Antibodies Anti-Phosphotyrosine (Anti-pY) T96-65R WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY)
Modification Antibodies Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated T96-65BR WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated
Primary Antibodies Anti-PKAc P51-63R WB View Anti-PKAc
Isoform Specific Antibodies Anti-PKC delta P64-63CR WB View Anti-PKC delta
Isoform Specific Antibodies Anti-PKC delta P64-63R WB View Anti-PKC delta
Primary Antibodies Anti-PKC delta/ theta P64-63DR WB View Anti-PKC delta/ theta
Isoform Specific Antibodies Anti-PKC mu P72-63R WB View Anti-PKC mu
Isoform Specific Antibodies Anti-PKC theta P74-63R WB View Anti-PKC theta
Primary Antibodies Anti-PKC zeta P75-63R WB View Anti-PKC zeta
Primary Antibodies Anti-PYK2 P92-63R WB View Anti-PYK2
Primary Antibodies Anti-RSK (pan) R15-63BR WB View Anti-RSK (pan)
Primary Antibodies Anti-RSK1 New Research Category R15-63CR WB, ELISA, ICC, IF View Anti-RSK1
Primary Antibodies Anti-RSK1 R15-63R WB View Anti-RSK1
Primary Antibodies Anti-SHP2 P38-63R WB View Anti-SHP2
Isoform Specific Antibodies Anti-SMAD2 S11-63R WB View Anti-SMAD2
Primary Antibodies Anti-STAT1 alpha New Research Category S52-63BR WB, ELISA, ICC, IP View Anti-STAT1 alpha
Primary Antibodies Anti-STAT1 beta New Research Category S52-63CR WB, ELISA View Anti-STAT1 beta
Isoform Specific Antibodies Anti-STAT1 beta S52-63R WB View Anti-STAT1 beta
Isoform Specific Antibodies Anti-STAT3 S54-63BR WB, IP View Anti-STAT3
Primary Antibodies Anti-STAT3 New Research Category S54-63CR WB, ELISA View Anti-STAT3
Isoform Specific Antibodies Anti-STAT3 S54-63R WB View Anti-STAT3
Isoform Specific Antibodies Anti-STAT4 S55-63R WB View Anti-STAT4
Isoform Specific Antibodies Anti-STAT5 S56-63BR WB View Anti-STAT5
Isoform Specific Antibodies Anti-STAT5 S56-63R WB View Anti-STAT5
Primary Antibodies Anti-STK39 (STLK3) New Research Category S51-63BR WB, ELISA, IHC View Anti-STK39 (STLK3)
Primary Antibodies Anti-STK39 (STLK3) New Research Category S51-63R WB, ELISA, IF, IHC View Anti-STK39 (STLK3)
Primary Antibodies Anti-TAB1 New Research Category T01-363R WB, ELISA, ICC, IF View Anti-TAB1
Primary Antibodies Anti-TAK1 New Research Category M15-63R WB, ELISA, IF, IHC View Anti-TAK1
Primary Antibodies Anti-Trail New Research Category T880-63R WB, ELISA, IHC View Anti-Trail
Primary Antibodies Anti-VAV V14-63R WB,IP View Anti-VAV
Primary Antibodies Anti-ZIP11 New Research Category Z45-363R WB, ELISA, IHC View Anti-ZIP11
Peptide Substrates Autocamtide 2 A15-58 Kinase Assay View Autocamtide 2
Growth Factors BMP-2 B851-40N Cell Assay View BMP-2
Growth Factors BMP-4 B853-40N Cell Assay View BMP-4
Cellular Proteins BMP2K Protein B03-11G Western Blot View BMP2K Protein
Active Kinases BMPR2, Active B06-11H Kinase Assay, Western Blot View BMPR2, Active
Active Kinases BRAF (V599E), Active B08-13G Kinase Assay, Western Blot View BRAF (V599E), Active
Active Kinases BRAF, Active B08-11G Kinase Assay, Western Blot View BRAF, Active
Assay Reagents Ca2+/Calmodulin Solution II, 10x C02-39B Kinase Assay View Ca2+/Calmodulin Solution II, 10x
Assay Reagents Ca2+/Calmodulin Solution, 10x C02-39 Kinase Assay View Ca2+/Calmodulin Solution, 10x
Cellular Proteins Calmodulin 1 Protein C01-30H Kinase Assay, Western Blot View Calmodulin 1 Protein
Active Kinases CAMK1 beta, Active C08-10G Kinase Assay, Western Blot View CAMK1 beta, Active
Active Kinases CAMK1 delta, Active C09-10G Kinase Assay, Western Blot View CAMK1 delta, Active
Active Kinases CAMK1 gamma, Active C10-10BG Kinase Assay, Western Blot View CAMK1 gamma, Active
Active Kinases CAMK1 gamma, Active C10-11G Kinase Assay, Western Blot View CAMK1 gamma, Active
Active Kinases CAMK1, Active C07-10G Kinase Assay, Western Blot View CAMK1, Active
Active Kinases CAMK2 alpha, Active C11-10G Kinase Assay, Western Blot View CAMK2 alpha, Active
Active Kinases CAMK2 beta, Active C12-10H Kinase Assay, Western Blot View CAMK2 beta, Active
Active Kinases CAMK2 delta, Active C13-10G Kinase Assay, Western Blot View CAMK2 delta, Active
Active Kinases CAMK2 gamma, Active C14-10G Kinase Assay, Western Blot View CAMK2 gamma, Active
Active Kinases CAMK4, Active C15-10G Kinase Assay, Western Blot View CAMK4, Active
Active Kinases CAMKK1, Active C17-10G Kinase Assay, Western Blot View CAMKK1, Active
Active Kinases CAMKK2, Active C18-10G Kinase Assay, Western Blot View CAMKK2, Active
Cellular Proteins CaMKPase Protein P06-34G Western Blot View CaMKPase Protein
Assay Reagents cAMP Solution A47-09 Enzyme Assay View cAMP Solution
Active Kinases CASK, Active C19-11G Kinase Assay, Western Blot View CASK, Active
Peptide Substrates CATCHtide C02-58 Kinase Assay View CATCHtide
Transcription Proteins CBP Protein C07-31G Western Blot View CBP Protein
G-Proteins CDC42 Protein C08-30G Kinase Assay, Western Blot View CDC42 Protein
Assay Reagents cGMP Solution G47-09 Enzyme Assay View cGMP Solution
Active Kinases COT, Active M16-11G Kinase Assay, Western Blot View COT, Active
Unactive Kinases COT, Unactive M16-15G Kinase Assay, Western Blot View COT, Unactive
Transcription Proteins CREB1 Protein C49-55G Kinase Assay, Western Blot View CREB1 Protein
Peptide Substrates CREBtide C50-58 Kinase Assay View CREBtide
Active Kinases DAPK1, Active D01-11G Kinase Assay, Western Blot View DAPK1, Active
Active Kinases DAPK2, Active D02-10G Kinase Assay, Western Blot View DAPK2, Active
Active Kinases DAPK3, Active D03-10G Kinase Assay, Western Blot View DAPK3, Active
Active Kinases DCAMKL1, Active D14-10G Kinase Assay, Western Blot View DCAMKL1, Active
Active Kinases DCAMKL2, Active D15-11G Kinase Assay, Western Blot View DCAMKL2, Active
Cellular Proteins DLK Protein M20-31G Western Blot View DLK Protein
Active Kinases EGFR (L858R), Active E10-12BG Kinase Assay, Western Blot View EGFR (L858R), Active
Active Kinases EGFR (L861Q), Active E10-12CG Kinase Assay, Western Blot View EGFR (L861Q), Active
Active Kinases EGFR (T790M L858R), Active E10-12DG Kinase Assay, Western Blot View EGFR (T790M L858R), Active
Active Kinases EGFR (T790M), Active E10-12EG Kinase Assay, Western Blot View EGFR (T790M), Active
Active Kinases EGFR, Active E10-11G Kinase Assay, Western Blot View EGFR, Active
Cellular Proteins EIF4E Protein E34-30G Kinase Assay, Western Blot View EIF4E Protein
Transcription Proteins ELK1 Protein E64-30G Kinase Assay, Western Blot View ELK1 Protein
Protein Substrates ERK1 (K71A) Protein M29-16H Kinase Assay, Western Blot View ERK1 (K71A) Protein
Active Kinases ERK1, Active M29-10G Kinase Assay, Western Blot View ERK1, Active
Active Kinases ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Unactive Kinases ERK1, Unactive M29-14G Kinase Assay, Western Blot View ERK1, Unactive
Unactive Kinases ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Active Kinases ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Unactive Kinases ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Unactive Kinases ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Active Kinases ERK5, Active M32-10G Kinase Assay, Western Blot View ERK5, Active
Active Kinases FAK, Active P91-10G Kinase Assay, Western Blot View FAK, Active
Active Kinases FAK, Active P91-11H Kinase Assay, Western Blot View FAK, Active
Active Kinases FGFR1 (FLT2), Active F04-11G Kinase Assay, Western Blot View FGFR1 (FLT2), Active
Active Kinases FGFR1 (V561M), Active F04-13G Kinase Assay, Western Blot View FGFR1 (V561M), Active
Active Kinases FGFR2, Active F05-11G Kinase Assay, Western Blot View FGFR2, Active
Active Kinases FGFR3 (K650E), Active F06-12CG Kinase Assay, Western Blot View FGFR3 (K650E), Active
Active Kinases FGFR3, Active F06-11G Kinase Assay, Western Blot View FGFR3, Active
Active Kinases FGFR4, Active F07-11G Kinase Assay, Western Blot View FGFR4, Active
Active Kinases FGR, Active F10-10G Kinase Assay, Western Blot View FGR, Active
Active Kinases FLT1, Active F11-11G Kinase Assay, Western Blot View FLT1, Active
Active Kinases FLT3 (D835Y), Active F12-12BG Kinase Assay, Western Blot View FLT3 (D835Y), Active
Active Kinases FLT3, Active F12-11G Kinase Assay, Western Blot View FLT3, Active
Active Kinases FLT4, Active F13-11G Kinase Assay, Western Blot View FLT4, Active
Transcription Proteins FOS Protein F66-30G Kinase Assay, Western Blot View FOS Protein
Protein Substrates FRS3 Protein F80-30G Kinase Assay, Western Blot View FRS3 Protein
Active Kinases FYN A, Active F15-10G Kinase Assay, Western Blot View FYN A, Active
Unactive Kinases FYN C, Unactive F15-14G Kinase Assay, Western Blot View FYN C, Unactive
Adaptor Proteins GAB1 Protein G03-30H Western Blot View GAB1 Protein
Adaptor Proteins GRB2 Protein G45-30G Western Blot View GRB2 Protein
Adaptor Proteins GRB7 Protein G45-30GG Western Blot View GRB7 Protein
Active Kinases GRK1, Active R03-10G Kinase Assay, Western Blot View GRK1, Active
Active Kinases GRK2, Active A14-10G Kinase Assay, Western Blot View GRK2, Active
Active Kinases GRK3, Active A15-11G Kinase Assay, Western Blot View GRK3, Active
Active Kinases GRK5, Active G03-10G Kinase Assay, Western Blot View GRK5, Active
Active Kinases GRK6, Active G04-10G Kinase Assay, Western Blot View GRK6, Active
Active Kinases GRK7, Active G05-10G Kinase Assay, Western Blot View GRK7, Active
Peptide Substrates GRKtide G46-58 Kinase Assay View GRKtide
Assay Reagents GTP Solution G50-09 Enzyme Assay View GTP Solution
Assay Reagents GTP Solution II G50-09B Enzyme Assay View GTP Solution II
Active Kinases HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
Active Kinases HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Protein Substrates Histone H1 Protein H10-54N Kinase Assay, Western Blot View Histone H1 Protein
Peptide Substrates Histone H3 Peptide (1-21) H12-58 Acetylation/Methylation Assays View Histone H3 Peptide (1-21)
Protein Substrates Histone H3 Protein H12-54N Kinase Assay, Western Blot View Histone H3 Protein
Peptide Substrates Histone H4 Peptide (1-21) H13-58 Acetylation/Methylation Assays View Histone H4 Peptide (1-21)
Active Kinases ICK, Active I01-10G Kinase Assay, Western Blot View ICK, Active
Active Kinases IGF1R, Active I02-11H Kinase Assay, Western Blot View IGF1R, Active
Peptide Substrates IGF1Rtide I15-58 Kinase Assay View IGF1Rtide
Growth Factors IL-18 I878-40N Cell Assay View IL-18
Growth Factors IL-2 I862-40N Cell Assay View IL-2
Growth Factors IL-8 (72AA) I868-40N Cell Assay View IL-8 (72AA)
Active Kinases InsR, Active I08-11G Kinase Assay, Western Blot View InsR, Active
Chemokines IP-10 I838-40N Cell Assay View IP-10
Active Kinases IRR, Active I07-11G Kinase Assay, Western Blot View IRR, Active
Protein Substrates IRS1 (C-Term) Protein I40-31G Kinase Assay, Western Blot View IRS1 (C-Term) Protein
Protein Substrates IRS1 (N-Term) Protein I40-35G Kinase Assay, Western Blot View IRS1 (N-Term) Protein
Active Acetyltransferases KAT2A (GCN5), Active K311-381G Acetyltransferase Assay View KAT2A (GCN5), Active
Active Acetyltransferases KAT2B (PCAF), Active K311-381BG Acetyltransferase Assay View KAT2B (PCAF), Active
Acetyl/Methyltransferase Proteins KAT3A (CREBBP) Protein K312-31G Western Blot View KAT3A (CREBBP) Protein
Active Acetyltransferases KAT3A (CREBBP), Active K312-381G Western Blot View KAT3A (CREBBP), Active
Acetyl/Methyltransferase Proteins KAT3B (EP300) Protein K312-31BG Western Blot View KAT3B (EP300) Protein
Acetyl/Methyltransferase Proteins KAT4 Protein K313-31G Western Blot View KAT4 Protein
Active Acetyltransferases KAT5 (TIP60), Active K314-380G Acetyltransferase Assay View KAT5 (TIP60), Active
Active Acetyltransferases KAT6B (MYST4), Active K315-381BG Acetyltransferase Assay View KAT6B (MYST4), Active
Active Acetyltransferases KAT7 (MYST2), Active K316-380G Acetyltransferase Assay View KAT7 (MYST2), Active
Acetyl/Methyltransferase Proteins KAT8 (MYST1) Protein K317-31G Western Blot View KAT8 (MYST1) Protein
Acetyl/Methyltransferase Proteins KAT9 (ELP3) Protein K318-30G Western Blot View KAT9 (ELP3) Protein
Active Kinases KDR, Active K01-11G Kinase Assay, Western Blot View KDR, Active
Active Kinases KSR1, Active K07-11G Kinase Assay, Western Blot View KSR1, Active
Growth Factors Leptin L833-40N Cell Assay View Leptin
Protein Substrates MBP Protein M42-51N Kinase Assay, Western Blot View MBP Protein
Protein Substrates MBP Protein M42-54G Kinase Assay, Western Blot View MBP Protein
Active Kinases MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Protein Substrates MEK1 (K97A), Unactive M02-16H Kinase Assay, Western Blot View MEK1 (K97A), Unactive
Active Kinases MEK1, Active M02-10G Kinase Assay, Western Blot View MEK1, Active
Unactive Kinases MEK1, Unactive M02-14BG Kinase Assay, Western Blot View MEK1, Unactive
Unactive Kinases MEK1, Unactive M02-14H Kinase Assay, Western Blot View MEK1, Unactive
Active Kinases MEK2, Active M03-10G Kinase Assay, Western Blot View MEK2, Active
Unactive Kinases MEK2, Unactive M03-14G Kinase Assay, Western Blot View MEK2, Unactive
Active Kinases MEKK1, Active M09-11G Kinase Assay, Western Blot View MEKK1, Active
Active Kinases MEKK2, Active M10-10G Kinase Assay, Western Blot View MEKK2, Active
Active Kinases MEKK3, Active M11-10G Kinase Assay, Western Blot View MEKK3, Active
Active Kinases MEKK6, Active M14-11G Kinase Assay, Western Blot View MEKK6, Active
Active Kinases MELK, Active M50-11G Kinase Assay, Western Blot View MELK, Active
Active Kinases MNK1, Active M54-10G Kinase Assay, Western Blot View MNK1, Active
Active Kinases MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Peptide Substrates Modified PKA Substrate C01-58B Kinase Assay View Modified PKA Substrate
Active Kinases NIK, Active M22-11G Kinase Assay, Western Blot View NIK, Active
Acetyl/Methyltransferase Proteins P300 Protein P07-31G Western Blot View P300 Protein
Active Kinases PAK1, Active P02-10BG Kinase Assay, Western Blot View PAK1, Active
Unactive Kinases PAK1, Unactive P02-14G Western Blot View PAK1, Unactive
Unactive Kinases PAK1, Unactive P02-17G Kinase Assay, Western Blot View PAK1, Unactive
Active Kinases PAK1/CDC42, Active P02-10G Kinase Assay, Western Blot View PAK1/CDC42, Active
Cellular Proteins PAK2 Protein P03-34G Western Blot View PAK2 Protein
Active Kinases PAK3, Active P04-10G Kinase Assay, Western Blot View PAK3, Active
Active Kinases PAK4, Active P05-10BG Kinase Assay, Western Blot View PAK4, Active
Active Kinases PAK6, Active P06-10G Kinase Assay, Western Blot View PAK6, Active
Active Kinases PAK7, Active P07-10G Kinase Assay, Western Blot View PAK7, Active
Peptide Substrates PAKtide P08-58 Kinase Assay View PAKtide
Active Kinases PASK, Active P08-11G Kinase Assay, Western Blot View PASK, Active
Acetyl/Methyltransferase Proteins PCNA Protein P11-30H Western Blot View PCNA Protein
Growth Factors PDGF P841-40N Cell Assay View PDGF
Active Kinases PDGFR alpha (D842V), Active P12-12BG Kinase Assay, Western Blot View PDGFR alpha (D842V), Active
Active Kinases PDGFR alpha (T674I), Active P12-12CG Kinase Assay, Western Blot View PDGFR alpha (T674I), Active
Active Kinases PDGFR alpha, Active P12-11G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR alpha, Active P12-18G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR beta, Active P13-11G Kinase Assay, Western Blot View PDGFR beta, Active
Active Kinases PEAK1, Active P18-11G Kinase Assay, Western Blot View PEAK1, Active
Unactive Kinases PEAK1, Unactive P18-14G Kinase Assay, Western Blot View PEAK1, Unactive
Peptide Substrates PKA Substrate C01-58 Kinase Assay View PKA Substrate
Active Kinases PKAc alpha, Active P51-10G Kinase Assay, Western Blot View PKAc alpha, Active
Active Kinases PKAc beta, Active P52-10G Kinase Assay, Western Blot View PKAc beta, Active
Active Kinases PKAc gamma, Active P53-10G Kinase Assay, Western Blot View PKAc gamma, Active
Active Kinases PKC alpha, Active P61-10G Kinase Assay, Western Blot View PKC alpha, Active
Active Kinases PKC alpha, Active P61-18G Kinase Assay, Western Blot View PKC alpha, Active
Active Kinases PKC beta I, Active P62-10G Kinase Assay, Western Blot View PKC beta I, Active
Active Kinases PKC beta II, Active P63-10G Kinase Assay, Western Blot View PKC beta II, Active
Active Kinases PKC delta, Active P64-10G Kinase Assay, Western Blot View PKC delta, Active
Active Kinases PKC epsilon, Active P65-10G Kinase Assay, Western Blot View PKC epsilon, Active
Active Kinases PKC eta, Active P67-10G Kinase Assay, Western Blot View PKC eta, Active
Active Kinases PKC gamma, Active P66-10G Kinase Assay, Western Blot View PKC gamma, Active
Active Kinases PKC iota, Active P68-10G Kinase Assay, Western Blot View PKC iota, Active
Assay Reagents PKC Lipid Activator, 10x L51-39 Kinase Assay View PKC Lipid Activator, 10x
Active Kinases PKC mu, Active P72-10G Kinase Assay, Western Blot View PKC mu, Active
Active Kinases PKC nu, Active P73-10G Kinase Assay, Western Blot View PKC nu, Active
Active Kinases PKC theta, Active P74-10G Kinase Assay, Western Blot View PKC theta, Active
Active Kinases PKC zeta, Active P75-10G Kinase Assay, Western Blot View PKC zeta, Active
Peptide Substrates PKCtide P15-58 Kinase Assay View PKCtide
Active Kinases PKD2 (G848E), Active New Research Category P76-12BG Kinase Assay, Western Blot View PKD2 (G848E), Active
Active Kinases PKD2 (G870E), Active P76-12CG Kinase Assay, Western Blot View PKD2 (G870E), Active
Active Kinases PKD2, Active P76-10G Kinase Assay, Western Blot View PKD2, Active
Active Kinases PKN2/PRK2, Active P71-10G Kinase Assay, Western Blot View PKN2/PRK2, Active
Active Kinases PKN3/PRK3, Active P69-10G Kinase Assay, Western Blot View PKN3/PRK3, Active
Peptide Substrates Poly (6:2:5:1 Ala,Glu,Lys,Tyr) Peptide P60-58 Kinase Assay View Poly (6:2:5:1 Ala,Glu,Lys,Tyr) Peptide
Active Phosphatases PP1A, Active P13-20G Phosphatase Assay, Western Blot View PP1A, Active
Active Phosphatases PP1B, Active P14-20G Phosphatase Assay, Western Blot View PP1B, Active
Active Phosphatases PP2Aalpha, Active P16-20G Phosphatase Assay, Western Blot View PP2Aalpha, Active
Cellular Proteins PP2Abeta Protein P17-34G Western Blot View PP2Abeta Protein
Cellular Proteins PP2B Protein P18-34G Western Blot View PP2B Protein
Active Phosphatases PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
Active Phosphatases PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
Cellular Proteins PRKAR1A Protein P57-30H Western Blot View PRKAR1A Protein
Cellular Proteins PRKAR1B Protein P59-30H Western Blot View PRKAR1B Protein
Active Kinases PRKX, Active P81-10G Kinase Assay, Western Blot View PRKX, Active
Cellular Proteins PSKH1 Protein P89-34G Western Blot View PSKH1 Protein
Cellular Proteins PTK7 Protein P95-35G Western Blot View PTK7 Protein
Cellular Proteins PTK9 Protein P97-34G Western Blot View PTK9 Protein
Active Phosphatases PTPN11 (SHP2), Active P38-21G Phosphatase Assay, Western Blot View PTPN11 (SHP2), Active
Active Kinases PYK2, Active P92-11H Kinase Assay, Western Blot View PYK2, Active
G-Proteins RAC1 Protein R03-30G Kinase Assay, Western Blot View RAC1 Protein
G-Proteins RAC2 Protein R04-30H Western Blot View RAC2 Protein
Active Kinases RAF1 (EE), Active R01-13G Kinase Assay, Western Blot View RAF1 (EE), Active
G-Proteins RAS Protein R05-30G Kinase Assay, Western Blot View RAS Protein
G-Proteins RGS1 Protein R39-30H Western Blot View RGS1 Protein
G-Proteins RHEB Protein R42-30H Kinase Assay, Western Blot View RHEB Protein
G-Proteins RhoA Protein R44-30H Kinase Assay, Western Blot View RhoA Protein
G-Proteins RhoC Protein R44-30CH Kinase Assay, Western Blot View RhoC Protein
G-Proteins RhoD Protein R44-30DH Kinase Assay, Western Blot View RhoD Protein
Peptide Substrates RSK Substrate S06-58 Kinase Assay View RSK Substrate
Active Kinases RSK1, Active R15-10G Kinase Assay, Western Blot View RSK1, Active
Active Kinases RSK2 (I416V), Active New Research Category R17-12BG Kinase Assay, Western Blot View RSK2 (I416V), Active
Active Kinases RSK2 (L608F), Active New Research Category R17-12CG Kinase Assay, Western Blot View RSK2 (L608F), Active
Active Kinases RSK2 (Y483C), Active New Research Category R17-12DG Kinase Assay, Western Blot View RSK2 (Y483C), Active
Active Kinases RSK2, Active R17-10G Kinase Assay, Western Blot View RSK2, Active
Active Kinases RSK3, Active R16-10G Kinase Assay, Western Blot View RSK3, Active
Chemokines SDF-1 S821-40N Cell Assay View SDF-1
Transcription Proteins SMAD1 Protein S10-30G Kinase Assay, Western Blot View SMAD1 Protein
Transcription Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
Transcription Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
Transcription Proteins SMAD4 Protein S13-30G Kinase Assay, Western Blot View SMAD4 Protein
Transcription Proteins SMAD5 Protein S14-30G Kinase Assay, Western Blot View SMAD5 Protein
Transcription Proteins SMAD9 Protein S17-30G Western Blot View SMAD9 Protein
Peptide Substrates SRC Substrate S30-58 Kinase Assay View SRC Substrate
Active Kinases SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Active Kinases SRC, Active S19-18G Kinase Assay, Western Blot View SRC, Active
Active Kinases SRMS, Active S20-11G Kinase Assay, Western Blot View SRMS, Active
Transcription Proteins STAT1 alpha Protein S52-50G Western Blot View STAT1 alpha Protein
Transcription Proteins STAT1 beta Protein S52-54G Kinase Assay, Western Blot View STAT1 beta Protein
Transcription Proteins STAT2 Protein S53-54G Kinase Assay, Western Blot View STAT2 Protein
Transcription Proteins STAT3 Protein S54-54G Kinase Assay, Western Blot View STAT3 Protein
Transcription Proteins STAT3 Protein S54-54H Kinase Assay, Western Blot View STAT3 Protein
Transcription Proteins STAT4 Protein S55-54H Kinase Assay, Western Blot View STAT4 Protein
Transcription Proteins STAT5 Protein S56-54H Kinase Assay, Western Blot View STAT5 Protein
Transcription Proteins STAT6 Protein S57-30G Kinase Assay, Western Blot View STAT6 Protein
Cellular Proteins STK16 Protein S31-34G Western Blot View STK16 Protein
Active Kinases STK19, Active S35-10G Kinase Assay, Western Blot View STK19, Active
Cellular Proteins STK31 Protein S45-35G Western Blot View STK31 Protein
Active Kinases STK32B (YANK2), Active Y04-10G Kinase Assay, Western Blot View STK32B (YANK2), Active
Active Kinases STK32C (YANK3), Active Y05-11G Kinase Assay, Western Blot View STK32C (YANK3), Active
Active Kinases STK33, Active S46-10G Kinase Assay, Western Blot View STK33, Active
Cellular Proteins STK35 (CLIK1) Protein S47-35G Western Blot View STK35 (CLIK1) Protein
Active Kinases STK36, Active S48-11G Kinase Assay, Western Blot View STK36, Active
Active Kinases STK39 (STLK3), Active S51-10H Kinase Assay, Western Blot View STK39 (STLK3), Active
Cellular Proteins STK9 Protein C46-31G Western Blot View STK9 Protein
Active Kinases TAK1-TAB1, Active M15-13G Kinase Assay, Western Blot View TAK1-TAB1, Active
Growth Factors TGFB1 T831-40N Cell Assay View TGFB1
Growth Factors TGFB3 T833-40CN Cell Assay View TGFB3
Active Kinases TGFBR1 (ALK5), Active T07-11G Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Peptide Substrates TGFBR1 Peptide T36-58 Peptide Substrate View TGFBR1 Peptide
Unactive Kinases TGFBR1, Unactive T07-35G Kinase Assay, Western Blot View TGFBR1, Unactive
Active Kinases TGFBR2, Active T08-11G Kinase Assay, Western Blot View TGFBR2, Active
Peptide Substrates Thr-phosphopeptide T69-58 Phosphatase Assay View Thr-phosphopeptide
Cytokines TNF-alpha T860-40N Cell Assay View TNF-alpha
Cytokines TNFB T861-40N Cell Assay View TNFB
Cytokines TRAIL T880-40N Cell Assay View TRAIL
Peptide Substrates Tyr-phosphopeptide-2 T70-58 Phosphatase Assay View Tyr-phosphopeptide-2
Cellular Proteins VAV1 Protein New Research Category V14-31G Western Blot View VAV1 Protein
Active Kinases VRK1, Active V01-10G Kinase Assay, Western Blot View VRK1, Active
Active Kinases VRK2, Active V02-11G Kinase Assay, Western Blot View VRK2, Active
Cellular Proteins VRK3 Protein V03-30G Western Blot View VRK3 Protein
Active Kinases YES1, Active Y01-10G Kinase Assay, Western Blot View YES1, Active
Active Kinases ZAK, Active Z01-10G Kinase Assay, Western Blot View ZAK, Active
Peptide Substrates ZIPtide Z16-58 Kinase Assay View ZIPtide
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Peptide Substrates Acetylated Histone H3 Peptide I H12-358 Acetylation/Methylation Assays View Acetylated Histone H3 Peptide I
Peptide Substrates Acetylated Histone H4 Peptide I H13-358 Acetylation/Methylation Assays View Acetylated Histone H4 Peptide I
Assay Reagents Acetyltransferase Assay Buffer A01-09 Acetyltransferase Assay View Acetyltransferase Assay Buffer
Assay Reagents Acetyltransferase Dilution Buffer A21-09 Acetyltransferase Assay View Acetyltransferase Dilution Buffer
Active Kinases ACK, Active A05-11G Kinase Assay, Western Blot View ACK, Active
Primary Antibodies Anti-ASK1 M13-60BM WB View Anti-ASK1
Primary Antibodies Anti-ASK1 M13-60M WB View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63BR WB, ELISA, ICC, IF View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63CR WB, ELISA View Anti-ASK1
Primary Antibodies Anti-ASK1 New Research Category M13-63R WB, ELISA, ICC, IF View Anti-ASK1
Primary Antibodies Anti-BRAF New Research Category B08-63R WB, ELISA View Anti-BRAF
Isoform Specific Antibodies Anti-CAMK1 C07-60M WB View Anti-CAMK1
Primary Antibodies Anti-CASK New Research Category C19-63R WB, ELISA, IF View Anti-CASK
Primary Antibodies Anti-CDC25A C04-63R WB View Anti-CDC25A
Primary Antibodies Anti-CDC42 New Research Category C08-363R WB, ELISA View Anti-CDC42
Primary Antibodies Anti-CREB C49-63R WB, IP View Anti-CREB
Primary Antibodies Anti-DLK1 New Research Category M20-63R WB, ELISA View Anti-DLK1
Primary Antibodies Anti-DOK1 D42-63R WB View Anti-DOK1
Primary Antibodies Anti-EGFR E10-63BR WB View Anti-EGFR
Primary Antibodies Anti-EGFR E10-63R WB View Anti-EGFR
Primary Antibodies Anti-eIF4E E34-63R WB View Anti-eIF4E
Primary Antibodies Anti-ELK1 E64-63R WB View Anti-ELK1
Isoform Specific Antibodies Anti-ERK1 M29-60BM WB, IP View Anti-ERK1
Primary Antibodies Anti-ERK1 M29-60CM IP View Anti-ERK1
Isoform Specific Antibodies Anti-ERK1 M29-60M WB, IP View Anti-ERK1
Primary Antibodies Anti-ERK1/2 M29-60EM WB View Anti-ERK1/2
Primary Antibodies Anti-ERK2 M28-63R WB View Anti-ERK2
Primary Antibodies Anti-FLT3 New Research Category F12-63R WB, ELISA, IF View Anti-FLT3
Primary Antibodies Anti-GAB1 G03-63R WB View Anti-GAB1
Primary Antibodies Anti-IRS1 New Research Category I40-363R WB, ELISA, ICC, IF View Anti-IRS1
Isoform Specific Antibodies Anti-MEK1 M02-60M WB, IP View Anti-MEK1
Primary Antibodies Anti-MEK1/2 M02-63R WB View Anti-MEK1/2
Isoform Specific Antibodies Anti-MEK2 M03-63R WB View Anti-MEK2
Primary Antibodies Anti-NIK New Research Category N22-63R WB, ELISA View Anti-NIK
Isoform Specific Antibodies Anti-PAK1 P02-63R WB View Anti-PAK1
Primary Antibodies Anti-PAK2 New Research Category P03-63BR WB, ELISA, IF, IHC View Anti-PAK2
Primary Antibodies Anti-PAK2 New Research Category P03-63R WB, ELISA, IF, IHC View Anti-PAK2
Primary Antibodies Anti-PAK4 New Research Category P05-163R WB, ELISA, ICC, IF View Anti-PAK4
Primary Antibodies Anti-PAK6 New Research Category P06-63R WB, ELISA, IF, IHC View Anti-PAK6
Primary Antibodies Anti-PAK7 New Research Category P07-63R WB, ELISA, ICC, IF View Anti-PAK7
Primary Antibodies Anti-PDFGB New Research Category P842-63R WB, ELISA View Anti-PDFGB
Modification Antibodies Anti-Phosphoserine (Anti-pS) S95-65R WB, ELISA, IP, IHC View Anti-Phosphoserine (Anti-pS)
Modification Antibodies Anti-Phosphoserine (Anti-pS), Biotin Conjugated S95-65BR WB, ELISA View Anti-Phosphoserine (Anti-pS), Biotin Conjugated
Modification Antibodies Anti-Phosphothreonine (Anti-pT) T95-65R WB, ELISA, IP, IHC View Anti-Phosphothreonine (Anti-pT)
Modification Antibodies Anti-Phosphothreonine (Anti-pT), Biotin Conjugated T95-65BR WB, ELISA View Anti-Phosphothreonine (Anti-pT), Biotin Conjugated
Modification Antibodies Anti-Phosphotyrosine (Anti-pY) T96-65R WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY)
Modification Antibodies Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated T96-65BR WB, ELISA, IHC, IP View Anti-Phosphotyrosine (Anti-pY), Biotin Conjugated
Primary Antibodies Anti-PKAc P51-63R WB View Anti-PKAc
Isoform Specific Antibodies Anti-PKC delta P64-63CR WB View Anti-PKC delta
Isoform Specific Antibodies Anti-PKC delta P64-63R WB View Anti-PKC delta
Primary Antibodies Anti-PKC delta/ theta P64-63DR WB View Anti-PKC delta/ theta
Isoform Specific Antibodies Anti-PKC mu P72-63R WB View Anti-PKC mu
Isoform Specific Antibodies Anti-PKC theta P74-63R WB View Anti-PKC theta
Primary Antibodies Anti-PKC zeta P75-63R WB View Anti-PKC zeta
Primary Antibodies Anti-PYK2 P92-63R WB View Anti-PYK2
Primary Antibodies Anti-RSK (pan) R15-63BR WB View Anti-RSK (pan)
Primary Antibodies Anti-RSK1 New Research Category R15-63CR WB, ELISA, ICC, IF View Anti-RSK1
Primary Antibodies Anti-RSK1 R15-63R WB View Anti-RSK1
Primary Antibodies Anti-SHP2 P38-63R WB View Anti-SHP2
Isoform Specific Antibodies Anti-SMAD2 S11-63R WB View Anti-SMAD2
Primary Antibodies Anti-STAT1 alpha New Research Category S52-63BR WB, ELISA, ICC, IP View Anti-STAT1 alpha
Primary Antibodies Anti-STAT1 beta New Research Category S52-63CR WB, ELISA View Anti-STAT1 beta
Isoform Specific Antibodies Anti-STAT1 beta S52-63R WB View Anti-STAT1 beta
Isoform Specific Antibodies Anti-STAT3 S54-63BR WB, IP View Anti-STAT3
Primary Antibodies Anti-STAT3 New Research Category S54-63CR WB, ELISA View Anti-STAT3
Isoform Specific Antibodies Anti-STAT3 S54-63R WB View Anti-STAT3
Isoform Specific Antibodies Anti-STAT4 S55-63R WB View Anti-STAT4
Isoform Specific Antibodies Anti-STAT5 S56-63BR WB View Anti-STAT5
Isoform Specific Antibodies Anti-STAT5 S56-63R WB View Anti-STAT5
Primary Antibodies Anti-STK39 (STLK3) New Research Category S51-63BR WB, ELISA, IHC View Anti-STK39 (STLK3)
Primary Antibodies Anti-STK39 (STLK3) New Research Category S51-63R WB, ELISA, IF, IHC View Anti-STK39 (STLK3)
Primary Antibodies Anti-TAB1 New Research Category T01-363R WB, ELISA, ICC, IF View Anti-TAB1
Primary Antibodies Anti-TAK1 New Research Category M15-63R WB, ELISA, IF, IHC View Anti-TAK1
Primary Antibodies Anti-Trail New Research Category T880-63R WB, ELISA, IHC View Anti-Trail
Primary Antibodies Anti-VAV V14-63R WB,IP View Anti-VAV
Primary Antibodies Anti-ZIP11 New Research Category Z45-363R WB, ELISA, IHC View Anti-ZIP11
Peptide Substrates Autocamtide 2 A15-58 Kinase Assay View Autocamtide 2
Growth Factors BMP-2 B851-40N Cell Assay View BMP-2
Growth Factors BMP-4 B853-40N Cell Assay View BMP-4
Cellular Proteins BMP2K Protein B03-11G Western Blot View BMP2K Protein
Active Kinases BMPR2, Active B06-11H Kinase Assay, Western Blot View BMPR2, Active
Active Kinases BRAF (V599E), Active B08-13G Kinase Assay, Western Blot View BRAF (V599E), Active
Active Kinases BRAF, Active B08-11G Kinase Assay, Western Blot View BRAF, Active
Assay Reagents Ca2+/Calmodulin Solution II, 10x C02-39B Kinase Assay View Ca2+/Calmodulin Solution II, 10x
Assay Reagents Ca2+/Calmodulin Solution, 10x C02-39 Kinase Assay View Ca2+/Calmodulin Solution, 10x
Cellular Proteins Calmodulin 1 Protein C01-30H Kinase Assay, Western Blot View Calmodulin 1 Protein
Active Kinases CAMK1 beta, Active C08-10G Kinase Assay, Western Blot View CAMK1 beta, Active
Active Kinases CAMK1 delta, Active C09-10G Kinase Assay, Western Blot View CAMK1 delta, Active
Active Kinases CAMK1 gamma, Active C10-10BG Kinase Assay, Western Blot View CAMK1 gamma, Active
Active Kinases CAMK1 gamma, Active C10-11G Kinase Assay, Western Blot View CAMK1 gamma, Active
Active Kinases CAMK1, Active C07-10G Kinase Assay, Western Blot View CAMK1, Active
Active Kinases CAMK2 alpha, Active C11-10G Kinase Assay, Western Blot View CAMK2 alpha, Active
Active Kinases CAMK2 beta, Active C12-10H Kinase Assay, Western Blot View CAMK2 beta, Active
Active Kinases CAMK2 delta, Active C13-10G Kinase Assay, Western Blot View CAMK2 delta, Active
Active Kinases CAMK2 gamma, Active C14-10G Kinase Assay, Western Blot View CAMK2 gamma, Active
Active Kinases CAMK4, Active C15-10G Kinase Assay, Western Blot View CAMK4, Active
Active Kinases CAMKK1, Active C17-10G Kinase Assay, Western Blot View CAMKK1, Active
Active Kinases CAMKK2, Active C18-10G Kinase Assay, Western Blot View CAMKK2, Active
Cellular Proteins CaMKPase Protein P06-34G Western Blot View CaMKPase Protein
Assay Reagents cAMP Solution A47-09 Enzyme Assay View cAMP Solution
Active Kinases CASK, Active C19-11G Kinase Assay, Western Blot View CASK, Active
Peptide Substrates CATCHtide C02-58 Kinase Assay View CATCHtide
Transcription Proteins CBP Protein C07-31G Western Blot View CBP Protein
G-Proteins CDC42 Protein C08-30G Kinase Assay, Western Blot View CDC42 Protein
Assay Reagents cGMP Solution G47-09 Enzyme Assay View cGMP Solution
Active Kinases COT, Active M16-11G Kinase Assay, Western Blot View COT, Active
Unactive Kinases COT, Unactive M16-15G Kinase Assay, Western Blot View COT, Unactive
Transcription Proteins CREB1 Protein C49-55G Kinase Assay, Western Blot View CREB1 Protein
Peptide Substrates CREBtide C50-58 Kinase Assay View CREBtide
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Active Kinases DAPK1, Active D01-11G Kinase Assay, Western Blot View DAPK1, Active
Active Kinases DAPK2, Active D02-10G Kinase Assay, Western Blot View DAPK2, Active
Active Kinases DAPK3, Active D03-10G Kinase Assay, Western Blot View DAPK3, Active
Active Kinases DCAMKL1, Active D14-10G Kinase Assay, Western Blot View DCAMKL1, Active
Active Kinases DCAMKL2, Active D15-11G Kinase Assay, Western Blot View DCAMKL2, Active
Cellular Proteins DLK Protein M20-31G Western Blot View DLK Protein
Active Kinases EGFR (L858R), Active E10-12BG Kinase Assay, Western Blot View EGFR (L858R), Active
Active Kinases EGFR (L861Q), Active E10-12CG Kinase Assay, Western Blot View EGFR (L861Q), Active
Active Kinases EGFR (T790M L858R), Active E10-12DG Kinase Assay, Western Blot View EGFR (T790M L858R), Active
Active Kinases EGFR (T790M), Active E10-12EG Kinase Assay, Western Blot View EGFR (T790M), Active
Active Kinases EGFR, Active E10-11G Kinase Assay, Western Blot View EGFR, Active
Cellular Proteins EIF4E Protein E34-30G Kinase Assay, Western Blot View EIF4E Protein
Transcription Proteins ELK1 Protein E64-30G Kinase Assay, Western Blot View ELK1 Protein
Protein Substrates ERK1 (K71A) Protein M29-16H Kinase Assay, Western Blot View ERK1 (K71A) Protein
Active Kinases ERK1, Active M29-10G Kinase Assay, Western Blot View ERK1, Active
Active Kinases ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Unactive Kinases ERK1, Unactive M29-14G Kinase Assay, Western Blot View ERK1, Unactive
Unactive Kinases ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Active Kinases ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Unactive Kinases ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Unactive Kinases ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Active Kinases ERK5, Active M32-10G Kinase Assay, Western Blot View ERK5, Active
Active Kinases FAK, Active P91-10G Kinase Assay, Western Blot View FAK, Active
Active Kinases FAK, Active P91-11H Kinase Assay, Western Blot View FAK, Active
Active Kinases FGFR1 (FLT2), Active F04-11G Kinase Assay, Western Blot View FGFR1 (FLT2), Active
Active Kinases FGFR1 (V561M), Active F04-13G Kinase Assay, Western Blot View FGFR1 (V561M), Active
Active Kinases FGFR2, Active F05-11G Kinase Assay, Western Blot View FGFR2, Active
Active Kinases FGFR3 (K650E), Active F06-12CG Kinase Assay, Western Blot View FGFR3 (K650E), Active
Active Kinases FGFR3, Active F06-11G Kinase Assay, Western Blot View FGFR3, Active
Active Kinases FGFR4, Active F07-11G Kinase Assay, Western Blot View FGFR4, Active
Active Kinases FGR, Active F10-10G Kinase Assay, Western Blot View FGR, Active
Active Kinases FLT1, Active F11-11G Kinase Assay, Western Blot View FLT1, Active
Active Kinases FLT3 (D835Y), Active F12-12BG Kinase Assay, Western Blot View FLT3 (D835Y), Active
Active Kinases FLT3, Active F12-11G Kinase Assay, Western Blot View FLT3, Active
Active Kinases FLT4, Active F13-11G Kinase Assay, Western Blot View FLT4, Active
Transcription Proteins FOS Protein F66-30G Kinase Assay, Western Blot View FOS Protein
Protein Substrates FRS3 Protein F80-30G Kinase Assay, Western Blot View FRS3 Protein
Active Kinases FYN A, Active F15-10G Kinase Assay, Western Blot View FYN A, Active
Unactive Kinases FYN C, Unactive F15-14G Kinase Assay, Western Blot View FYN C, Unactive
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Adaptor Proteins GAB1 Protein G03-30H Western Blot View GAB1 Protein
Adaptor Proteins GRB2 Protein G45-30G Western Blot View GRB2 Protein
Adaptor Proteins GRB7 Protein G45-30GG Western Blot View GRB7 Protein
Active Kinases GRK1, Active R03-10G Kinase Assay, Western Blot View GRK1, Active
Active Kinases GRK2, Active A14-10G Kinase Assay, Western Blot View GRK2, Active
Active Kinases GRK3, Active A15-11G Kinase Assay, Western Blot View GRK3, Active
Active Kinases GRK5, Active G03-10G Kinase Assay, Western Blot View GRK5, Active
Active Kinases GRK6, Active G04-10G Kinase Assay, Western Blot View GRK6, Active
Active Kinases GRK7, Active G05-10G Kinase Assay, Western Blot View GRK7, Active
Peptide Substrates GRKtide G46-58 Kinase Assay View GRKtide
Assay Reagents GTP Solution G50-09 Enzyme Assay View GTP Solution
Assay Reagents GTP Solution II G50-09B Enzyme Assay View GTP Solution II
Active Kinases HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
Active Kinases HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Protein Substrates Histone H1 Protein H10-54N Kinase Assay, Western Blot View Histone H1 Protein
Peptide Substrates Histone H3 Peptide (1-21) H12-58 Acetylation/Methylation Assays View Histone H3 Peptide (1-21)
Protein Substrates Histone H3 Protein H12-54N Kinase Assay, Western Blot View Histone H3 Protein
Peptide Substrates Histone H4 Peptide (1-21) H13-58 Acetylation/Methylation Assays View Histone H4 Peptide (1-21)
Active Kinases ICK, Active I01-10G Kinase Assay, Western Blot View ICK, Active
Active Kinases IGF1R, Active I02-11H Kinase Assay, Western Blot View IGF1R, Active
Peptide Substrates IGF1Rtide I15-58 Kinase Assay View IGF1Rtide
Growth Factors IL-18 I878-40N Cell Assay View IL-18
Growth Factors IL-2 I862-40N Cell Assay View IL-2
Growth Factors IL-8 (72AA) I868-40N Cell Assay View IL-8 (72AA)
Active Kinases InsR, Active I08-11G Kinase Assay, Western Blot View InsR, Active
Chemokines IP-10 I838-40N Cell Assay View IP-10
Active Kinases IRR, Active I07-11G Kinase Assay, Western Blot View IRR, Active
Protein Substrates IRS1 (C-Term) Protein I40-31G Kinase Assay, Western Blot View IRS1 (C-Term) Protein
Protein Substrates IRS1 (N-Term) Protein I40-35G Kinase Assay, Western Blot View IRS1 (N-Term) Protein
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Active Acetyltransferases KAT2A (GCN5), Active K311-381G Acetyltransferase Assay View KAT2A (GCN5), Active
Active Acetyltransferases KAT2B (PCAF), Active K311-381BG Acetyltransferase Assay View KAT2B (PCAF), Active
Acetyl/Methyltransferase Proteins KAT3A (CREBBP) Protein K312-31G Western Blot View KAT3A (CREBBP) Protein
Active Acetyltransferases KAT3A (CREBBP), Active K312-381G Western Blot View KAT3A (CREBBP), Active
Acetyl/Methyltransferase Proteins KAT3B (EP300) Protein K312-31BG Western Blot View KAT3B (EP300) Protein
Acetyl/Methyltransferase Proteins KAT4 Protein K313-31G Western Blot View KAT4 Protein
Active Acetyltransferases KAT5 (TIP60), Active K314-380G Acetyltransferase Assay View KAT5 (TIP60), Active
Active Acetyltransferases KAT6B (MYST4), Active K315-381BG Acetyltransferase Assay View KAT6B (MYST4), Active
Active Acetyltransferases KAT7 (MYST2), Active K316-380G Acetyltransferase Assay View KAT7 (MYST2), Active
Acetyl/Methyltransferase Proteins KAT8 (MYST1) Protein K317-31G Western Blot View KAT8 (MYST1) Protein
Acetyl/Methyltransferase Proteins KAT9 (ELP3) Protein K318-30G Western Blot View KAT9 (ELP3) Protein
Active Kinases KDR, Active K01-11G Kinase Assay, Western Blot View KDR, Active
Active Kinases KSR1, Active K07-11G Kinase Assay, Western Blot View KSR1, Active
Growth Factors Leptin L833-40N Cell Assay View Leptin
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Protein Substrates MBP Protein M42-51N Kinase Assay, Western Blot View MBP Protein
Protein Substrates MBP Protein M42-54G Kinase Assay, Western Blot View MBP Protein
Active Kinases MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Protein Substrates MEK1 (K97A), Unactive M02-16H Kinase Assay, Western Blot View MEK1 (K97A), Unactive
Active Kinases MEK1, Active M02-10G Kinase Assay, Western Blot View MEK1, Active
Unactive Kinases MEK1, Unactive M02-14BG Kinase Assay, Western Blot View MEK1, Unactive
Unactive Kinases MEK1, Unactive M02-14H Kinase Assay, Western Blot View MEK1, Unactive
Active Kinases MEK2, Active M03-10G Kinase Assay, Western Blot View MEK2, Active
Unactive Kinases MEK2, Unactive M03-14G Kinase Assay, Western Blot View MEK2, Unactive
Active Kinases MEKK1, Active M09-11G Kinase Assay, Western Blot View MEKK1, Active
Active Kinases MEKK2, Active M10-10G Kinase Assay, Western Blot View MEKK2, Active
Active Kinases MEKK3, Active M11-10G Kinase Assay, Western Blot View MEKK3, Active
Active Kinases MEKK6, Active M14-11G Kinase Assay, Western Blot View MEKK6, Active
Active Kinases MELK, Active M50-11G Kinase Assay, Western Blot View MELK, Active
Active Kinases MNK1, Active M54-10G Kinase Assay, Western Blot View MNK1, Active
Active Kinases MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Peptide Substrates Modified PKA Substrate C01-58B Kinase Assay View Modified PKA Substrate
Active Kinases NIK, Active M22-11G Kinase Assay, Western Blot View NIK, Active
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Acetyl/Methyltransferase Proteins P300 Protein P07-31G Western Blot View P300 Protein
Active Kinases PAK1, Active P02-10BG Kinase Assay, Western Blot View PAK1, Active
Unactive Kinases PAK1, Unactive P02-14G Western Blot View PAK1, Unactive
Unactive Kinases PAK1, Unactive P02-17G Kinase Assay, Western Blot View PAK1, Unactive
Active Kinases PAK1/CDC42, Active P02-10G Kinase Assay, Western Blot View PAK1/CDC42, Active
Cellular Proteins PAK2 Protein P03-34G Western Blot View PAK2 Protein
Active Kinases PAK3, Active P04-10G Kinase Assay, Western Blot View PAK3, Active
Active Kinases PAK4, Active P05-10BG Kinase Assay, Western Blot View PAK4, Active
Active Kinases PAK6, Active P06-10G Kinase Assay, Western Blot View PAK6, Active
Active Kinases PAK7, Active P07-10G Kinase Assay, Western Blot View PAK7, Active
Peptide Substrates PAKtide P08-58 Kinase Assay View PAKtide
Active Kinases PASK, Active P08-11G Kinase Assay, Western Blot View PASK, Active
Acetyl/Methyltransferase Proteins PCNA Protein P11-30H Western Blot View PCNA Protein
Growth Factors PDGF P841-40N Cell Assay View PDGF
Active Kinases PDGFR alpha (D842V), Active P12-12BG Kinase Assay, Western Blot View PDGFR alpha (D842V), Active
Active Kinases PDGFR alpha (T674I), Active P12-12CG Kinase Assay, Western Blot View PDGFR alpha (T674I), Active
Active Kinases PDGFR alpha, Active P12-11G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR alpha, Active P12-18G Kinase Assay, Western Blot View PDGFR alpha, Active
Active Kinases PDGFR beta, Active P13-11G Kinase Assay, Western Blot View PDGFR beta, Active
Active Kinases PEAK1, Active P18-11G Kinase Assay, Western Blot View PEAK1, Active
Unactive Kinases PEAK1, Unactive P18-14G Kinase Assay, Western Blot View PEAK1, Unactive
Peptide Substrates PKA Substrate C01-58 Kinase Assay View PKA Substrate
Active Kinases PKAc alpha, Active P51-10G Kinase Assay, Western Blot View PKAc alpha, Active
Active Kinases PKAc beta, Active P52-10G Kinase Assay, Western Blot View PKAc beta, Active
Active Kinases PKAc gamma, Active P53-10G Kinase Assay, Western Blot View PKAc gamma, Active
Active Kinases PKC alpha, Active P61-10G Kinase Assay, Western Blot View PKC alpha, Active
Active Kinases PKC alpha, Active P61-18G Kinase Assay, Western Blot View PKC alpha, Active
Active Kinases PKC beta I, Active P62-10G Kinase Assay, Western Blot View PKC beta I, Active
Active Kinases PKC beta II, Active P63-10G Kinase Assay, Western Blot View PKC beta II, Active
Active Kinases PKC delta, Active P64-10G Kinase Assay, Western Blot View PKC delta, Active
Active Kinases PKC epsilon, Active P65-10G Kinase Assay, Western Blot View PKC epsilon, Active
Active Kinases PKC eta, Active P67-10G Kinase Assay, Western Blot View PKC eta, Active
Active Kinases PKC gamma, Active P66-10G Kinase Assay, Western Blot View PKC gamma, Active
Active Kinases PKC iota, Active P68-10G Kinase Assay, Western Blot View PKC iota, Active
Assay Reagents PKC Lipid Activator, 10x L51-39 Kinase Assay View PKC Lipid Activator, 10x
Active Kinases PKC mu, Active P72-10G Kinase Assay, Western Blot View PKC mu, Active
Active Kinases PKC nu, Active P73-10G Kinase Assay, Western Blot View PKC nu, Active
Active Kinases PKC theta, Active P74-10G Kinase Assay, Western Blot View PKC theta, Active
Active Kinases PKC zeta, Active P75-10G Kinase Assay, Western Blot View PKC zeta, Active
Peptide Substrates PKCtide P15-58 Kinase Assay View PKCtide
Active Kinases PKD2 (G848E), Active New Research Category P76-12BG Kinase Assay, Western Blot View PKD2 (G848E), Active
Active Kinases PKD2 (G870E), Active P76-12CG Kinase Assay, Western Blot View PKD2 (G870E), Active
Active Kinases PKD2, Active P76-10G Kinase Assay, Western Blot View PKD2, Active
Active Kinases PKN2/PRK2, Active P71-10G Kinase Assay, Western Blot View PKN2/PRK2, Active
Active Kinases PKN3/PRK3, Active P69-10G Kinase Assay, Western Blot View PKN3/PRK3, Active
Peptide Substrates Poly (6:2:5:1 Ala,Glu,Lys,Tyr) Peptide P60-58 Kinase Assay View Poly (6:2:5:1 Ala,Glu,Lys,Tyr) Peptide
Active Phosphatases PP1A, Active P13-20G Phosphatase Assay, Western Blot View PP1A, Active
Active Phosphatases PP1B, Active P14-20G Phosphatase Assay, Western Blot View PP1B, Active
Active Phosphatases PP2Aalpha, Active P16-20G Phosphatase Assay, Western Blot View PP2Aalpha, Active
Cellular Proteins PP2Abeta Protein P17-34G Western Blot View PP2Abeta Protein
Cellular Proteins PP2B Protein P18-34G Western Blot View PP2B Protein
Active Phosphatases PP2Calpha, Active P02-20G Phosphatase Assay, Western Blot View PP2Calpha, Active
Active Phosphatases PP2Cgamma, Active P07-20G Phosphatase Assay, Western Blot View PP2Cgamma, Active
Cellular Proteins PRKAR1A Protein P57-30H Western Blot View PRKAR1A Protein
Cellular Proteins PRKAR1B Protein P59-30H Western Blot View PRKAR1B Protein
Active Kinases PRKX, Active P81-10G Kinase Assay, Western Blot View PRKX, Active
Cellular Proteins PSKH1 Protein P89-34G Western Blot View PSKH1 Protein
Cellular Proteins PTK7 Protein P95-35G Western Blot View PTK7 Protein
Cellular Proteins PTK9 Protein P97-34G Western Blot View PTK9 Protein
Active Phosphatases PTPN11 (SHP2), Active P38-21G Phosphatase Assay, Western Blot View PTPN11 (SHP2), Active
Active Kinases PYK2, Active P92-11H Kinase Assay, Western Blot View PYK2, Active
G-Proteins RAC1 Protein R03-30G Kinase Assay, Western Blot View RAC1 Protein
G-Proteins RAC2 Protein R04-30H Western Blot View RAC2 Protein
Active Kinases RAF1 (EE), Active R01-13G Kinase Assay, Western Blot View RAF1 (EE), Active
G-Proteins RAS Protein R05-30G Kinase Assay, Western Blot View RAS Protein
G-Proteins RGS1 Protein R39-30H Western Blot View RGS1 Protein
G-Proteins RHEB Protein R42-30H Kinase Assay, Western Blot View RHEB Protein
G-Proteins RhoA Protein R44-30H Kinase Assay, Western Blot View RhoA Protein
G-Proteins RhoC Protein R44-30CH Kinase Assay, Western Blot View RhoC Protein
G-Proteins RhoD Protein R44-30DH Kinase Assay, Western Blot View RhoD Protein
Peptide Substrates RSK Substrate S06-58 Kinase Assay View RSK Substrate
Active Kinases RSK1, Active R15-10G Kinase Assay, Western Blot View RSK1, Active
Active Kinases RSK2 (I416V), Active New Research Category R17-12BG Kinase Assay, Western Blot View RSK2 (I416V), Active
Active Kinases RSK2 (L608F), Active New Research Category R17-12CG Kinase Assay, Western Blot View RSK2 (L608F), Active
Active Kinases RSK2 (Y483C), Active New Research Category R17-12DG Kinase Assay, Western Blot View RSK2 (Y483C), Active
Active Kinases RSK2, Active R17-10G Kinase Assay, Western Blot View RSK2, Active
Active Kinases RSK3, Active R16-10G Kinase Assay, Western Blot View RSK3, Active
Chemokines SDF-1 S821-40N Cell Assay View SDF-1
Transcription Proteins SMAD1 Protein S10-30G Kinase Assay, Western Blot View SMAD1 Protein
Transcription Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
Transcription Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
Transcription Proteins SMAD4 Protein S13-30G Kinase Assay, Western Blot View SMAD4 Protein
Transcription Proteins SMAD5 Protein S14-30G Kinase Assay, Western Blot View SMAD5 Protein
Transcription Proteins SMAD9 Protein S17-30G Western Blot View SMAD9 Protein
Peptide Substrates SRC Substrate S30-58 Kinase Assay View SRC Substrate
Active Kinases SRC, Active S19-10G Kinase Assay, Western Blot View SRC, Active
Active Kinases SRC, Active S19-18G Kinase Assay, Western Blot View SRC, Active
Active Kinases SRMS, Active S20-11G Kinase Assay, Western Blot View SRMS, Active
Transcription Proteins STAT1 alpha Protein S52-50G Western Blot View STAT1 alpha Protein
Transcription Proteins STAT1 beta Protein S52-54G Kinase Assay, Western Blot View STAT1 beta Protein
Transcription Proteins STAT2 Protein S53-54G Kinase Assay, Western Blot View STAT2 Protein
Transcription Proteins STAT3 Protein S54-54G Kinase Assay, Western Blot View STAT3 Protein
Transcription Proteins STAT3 Protein S54-54H Kinase Assay, Western Blot View STAT3 Protein
Transcription Proteins STAT4 Protein S55-54H Kinase Assay, Western Blot View STAT4 Protein
Transcription Proteins STAT5 Protein S56-54H Kinase Assay, Western Blot View STAT5 Protein
Transcription Proteins STAT6 Protein S57-30G Kinase Assay, Western Blot View STAT6 Protein
Cellular Proteins STK16 Protein S31-34G Western Blot View STK16 Protein
Active Kinases STK19, Active S35-10G Kinase Assay, Western Blot View STK19, Active
Cellular Proteins STK31 Protein S45-35G Western Blot View STK31 Protein
Active Kinases STK32B (YANK2), Active Y04-10G Kinase Assay, Western Blot View STK32B (YANK2), Active
Active Kinases STK32C (YANK3), Active Y05-11G Kinase Assay, Western Blot View STK32C (YANK3), Active
Active Kinases STK33, Active S46-10G Kinase Assay, Western Blot View STK33, Active
Cellular Proteins STK35 (CLIK1) Protein S47-35G Western Blot View STK35 (CLIK1) Protein
Active Kinases STK36, Active S48-11G Kinase Assay, Western Blot View STK36, Active
Active Kinases STK39 (STLK3), Active S51-10H Kinase Assay, Western Blot View STK39 (STLK3), Active
Cellular Proteins STK9 Protein C46-31G Western Blot View STK9 Protein
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Active Kinases TAK1-TAB1, Active M15-13G Kinase Assay, Western Blot View TAK1-TAB1, Active
Growth Factors TGFB1 T831-40N Cell Assay View TGFB1
Growth Factors TGFB3 T833-40CN Cell Assay View TGFB3
Active Kinases TGFBR1 (ALK5), Active T07-11G Kinase Assay, Western Blot View TGFBR1 (ALK5), Active
Peptide Substrates TGFBR1 Peptide T36-58 Peptide Substrate View TGFBR1 Peptide
Unactive Kinases TGFBR1, Unactive T07-35G Kinase Assay, Western Blot View TGFBR1, Unactive
Active Kinases TGFBR2, Active T08-11G Kinase Assay, Western Blot View TGFBR2, Active
Peptide Substrates Thr-phosphopeptide T69-58 Phosphatase Assay View Thr-phosphopeptide
Cytokines TNF-alpha T860-40N Cell Assay View TNF-alpha
Cytokines TNFB T861-40N Cell Assay View TNFB
Cytokines TRAIL T880-40N Cell Assay View TRAIL
Peptide Substrates Tyr-phosphopeptide-2 T70-58 Phosphatase Assay View Tyr-phosphopeptide-2
Cellular Proteins VAV1 Protein New Research Category V14-31G Western Blot View VAV1 Protein
Active Kinases VRK1, Active V01-10G Kinase Assay, Western Blot View VRK1, Active
Active Kinases VRK2, Active V02-11G Kinase Assay, Western Blot View VRK2, Active
Cellular Proteins VRK3 Protein V03-30G Western Blot View VRK3 Protein
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Active Kinases YES1, Active Y01-10G Kinase Assay, Western Blot View YES1, Active
Active Kinases ZAK, Active Z01-10G Kinase Assay, Western Blot View ZAK, Active
Peptide Substrates ZIPtide Z16-58 Kinase Assay View ZIPtide
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30G Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 alpha/beta Protein Y71-30N Western Blot View 14-3-3 alpha/beta Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 epsilon Protein Y75-30N Western Blot View 14-3-3 epsilon Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30G Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 sigma Protein Y86-30N Western Blot View 14-3-3 sigma Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30G Western Blot View 14-3-3 zeta Protein
Cell Stress & Chaperone Proteins 14-3-3 zeta Protein Y92-30N Western Blot View 14-3-3 zeta Protein
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
ERK/MAPK Pathway Product Listing Found: Total 344 Products Matching Research Category ERK/MAPK Pathway
Product Type Product Name Catalog Number Application Pack Sizes
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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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