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Catalog Number |
Pack Size |
Price (USD) |
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| PAK7, Active |
P07-10G-05 |
5 ug |
$205 |
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Add to Cart |
| PAK7, Active |
P07-10G-10 |
10 ug |
$295 |
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Add to Cart |
| PAK7, Active |
P07-10G-BULK |
BULK |
CONTACT US |
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* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Recombinant full-length human PAK7 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
| Tag: |
GST tag |
| Expression System: |
Sf9 insect cells using baculovirus |
| Species: |
Human |
| Sequence: |
Full length |
| Genbank Number: |
NM_177990
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Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Kinase Assay, Western Blot
Molecular Weight: ~130 kDa
Gene Aliases: PAK5; KIAA1264; MGC26232
Scientific Background: PAK7 (also known as PAK5) is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus (1). The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.
References:
1. Pandey, A. et al: Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain.
Oncogene. 2002 May 30;21(24):3939-48.
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Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet. |
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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PAK7, Active Research Areas
The PAK7, Active product can be utilized in the following research areas, but not limited to:
Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases
| Product Type |
Product Name |
Catalog Number |
Application |
Pack Sizes |
| Signaling Proteins |
PAK1, Unactive |
P02-14G |
Western Blot |
View PAK1, Unactive
|
| Signaling Reagents |
Kinase Assay Buffer I |
K01-09 |
Kinase Assay |
View Kinase Assay Buffer I
|
| Signaling Reagents |
AKT (PKB) Substrate |
A05-58 |
Kinase Assay |
View AKT (PKB) Substrate
|
| Signaling Proteins |
CDC42 Protein |
C08-30G |
Kinase Assay, Western Blot |
View CDC42 Protein
|
| Enzymes |
ROCK1, Active |
R10-11G |
Kinase Assay, Western Blot |
View ROCK1, Active
|
| Enzymes |
ROCK2, Active |
R11-11G |
Kinase Assay, Western Blot |
View ROCK2, Active
|
| Enzymes |
PAK3, Active |
P04-10G |
Kinase Assay, Western Blot |
View PAK3, Active
|
| Signaling Proteins |
PAK1, Unactive |
P02-17G |
Kinase Assay, Western Blot |
View PAK1, Unactive
|
| Signaling Proteins |
RAC1 Protein |
R03-30G |
Kinase Assay, Western Blot |
View RAC1 Protein
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| Antibodies |
Anti-PAK1 |
P02-63R |
WB |
View Anti-PAK1
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| Enzymes |
PAK6, Active |
P06-10G |
Kinase Assay, Western Blot |
View PAK6, Active
|
| Enzymes |
PAK4, Active |
P05-10BG |
Kinase Assay, Western Blot |
View PAK4, Active
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| Enzymes |
PAK1, Active |
P02-10BG |
Kinase Assay, Western Blot |
View PAK1, Active
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| Signaling Proteins |
PAK2 Protein |
P03-34G |
Western Blot |
View PAK2 Protein
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