* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Human active form Leptin (22-167) was expressed in
E. coli cells and purified by proprietary chromatographic techniques.
: Recombinant protein stored in 1 X PBS, 10% glycerol.
Storage, Stability, and Shipping
: Stored at desiccated below -20o
C. It is stable at 4o
C between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
: Cell Assay
: Less than 0.1 ng/µg (IEU/µg) of Leptin.
: ~14.5 kDa
: OB; OBS; FLJ94114; LEP
: Leptin is a serum protein produced by adipocytes that play a main role in the regulation of body fat. Leptin is a growth factor in colonic epithelial cells and one that may provide a biological explanation for the observed associations between obesity, physical activity, and colon cancer (1). Leptin appears to be able to control the proliferation of both normal and malignant breast epithelial cells and used for normal mammary gland development (2).
1. Hardwick JC. et.al : Leptin is a growth factor for colonic epithelial cells. Gastroenterology. 2001 Jul;121(1):79-90.
2. X Hu. et.al: Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst. 2002 Nov 20;94(22):1704-11.
||Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Leptin Research Areas
The Leptin product can be utilized in the following research areas, but not limited to:
AKT/PKB Pathway, Cardiovascular Disease, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, Metabolic Disorder, p38 Pathway