MAPKAPK3 Active Enzymes Active Kinases


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MAPKAPK3, Active (M41-10G)

Catalog Number Pack Size Price (USD)  
MAPKAPK3, Active M41-10G-05 5 ug $205   MAPKAPK3, Active Add to Cart
MAPKAPK3, Active M41-10G-10 10 ug $295   MAPKAPK3, Active Add to Cart
MAPKAPK3, Active M41-10G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length human MAPKAPK3 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full Length
Genbank Number: NM_004635
   

Storage, Stability and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~69 kDa

Gene Aliases: 3PK; MAPKAP3; 3pK

Scientific Background: MAPKAPK3 is closely related to MAPKAPK2 sharing 72% nucleotide and 75% amino acid identity (1). MAPKAPK3 is activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of MAPKAPK3 as an integrative element of signaling in both mitogen and stress responses (2).

References
1. Sithanandam, G. et al: 3pK a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region. Molec. Cell. Biol. 16: 868-876, 1996.

2. Ludwig, S. et al: 3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Molec. Cell. Biol. 16: 6687-6697, 1996.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




MAPKAPK3, Active Research Areas

The MAPKAPK3, Active product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases



MAPKAPK3, Active Related Products Found: Total 13 Related Products
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Enzymes MAPKAPK2, Active M40-11G Kinase Assay, Western Blot View MAPKAPK2, Active
Signaling Proteins HSP27 Protein H30-54G Kinase Assay, Western Blot View HSP27 Protein
Signaling Proteins MAPKAPK2, Unactive M40-14G Kinase Assay, Western Blot View MAPKAPK2, Unactive
Signaling Proteins MAPKAPK3, Unactive M41-14G Kinase Assay, Western Blot View MAPKAPK3, Unactive
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Signaling Reagents HSP27tide H31-58 Kinase Assay View HSP27tide
Enzymes MST4, Active M59-10G Kinase Assay, Western Blot View MST4, Active
Enzymes MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
Signaling Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Signaling Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
Enzymes MAPKAPK2, Active M40-11H Kinase Assay, Western Blot View MAPKAPK2, Active
Antibodies Anti-MAPKAPK2/3 M40-63R WB View Anti-MAPKAPK2/3
Enzymes MAPKAPK5, Active M42-10G Kinase Assay, Western Blot View MAPKAPK5, Active


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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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