PIK3C2G Active Enzymes Active Kinases


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PIK3C2G, Active (P25-11G)

Catalog Number Pack Size Price (USD)  
PIK3C2G, Active P25-11G-05 5 ug $205   PIK3C2G, Active Add to Cart
PIK3C2G, Active P25-11G-10 10 ug $295   PIK3C2G, Active Add to Cart
PIK3C2G, Active P25-11G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant human PIK3C2G (468-1203) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: 468-1203
Genbank Number: BC130277
   

Storage, Stability and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~110 kDa

Gene Aliases: MGC163149; PI3K-C2GAMMA

Scientific Background: PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family which plays main roles in signaling pathways and involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking (1). PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions and the N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity (2).

References
1. Rozycka, M.et.al: cDNA cloning of a third human C2-domain-containing class II phosphoinositide 3-kinase, PI3K-C2-gamma, and chromosomal assignment of this gene (PIK3C2G) to 12p12. Genomics 54: 569-574, 1998.

2. Misawa, H. et.al: Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain. Biochem. Biophys. Res. Commun. 244: 531-539, 1998.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




PIK3C2G, Active Research Areas

The PIK3C2G, Active product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Lipid Kinases, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling



PIK3C2G, Active Related Products Found: Total 16 Related Products
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Enzymes PI3K (p110 alpha/p85 alpha), Active P27-18H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Enzymes PI3K (p110 beta/p85 alpha), Active P28-10H Kinase Assay, Western Blot View PI3K (p110 beta/p85 alpha), Active
Enzymes PI3K (p110 beta/p85 beta), Active P28-10BH Kinase Assay, Western Blot View PI3K (p110 beta/p85 beta), Active
Enzymes PI3K (p110 delta/p85 alpha), Active P30-10H Kinase Assay, Western Blot View PI3K (p110 delta/p85 alpha), Active
Enzymes PI3K (p120 gamma), Active P29-10H Kinase Assay, Western Blot View PI3K (p120 gamma), Active
Signaling Proteins PI3K (p85 alpha) Protein P31-30H Kinase Assay, Western Blot View PI3K (p85 alpha) Protein
Signaling Proteins PI3K (p85 beta) Protein P31-30BH Kinase Assay, Western Blot View PI3K (p85 beta) Protein
Enzymes PI4K2A, Active P21-10G Kinase Assay, Western Blot View PI4K2A, Active
Enzymes PI4K2B, Active P22-10G Kinase Assay, Western Blot View PI4K2B, Active
Signaling Proteins PI3K (p55 gamma) Protein P31-30CH Western Blot View PI3K (p55 gamma) Protein
Signaling Proteins PI3K (p65 alpha) Protein P31-31H Western Blot View PI3K (p65 alpha) Protein
Enzymes PI3K (p110 alpha/p55 gamma), Active P27-10CH Kinase Assay, Western Blot View PI3K (p110 alpha/p55 gamma), Active
Signaling Proteins PIK3C2B Protein P24-31BG Western Blot View PIK3C2B Protein


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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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