KAT7 (MYST2), Active (K316-380G)
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Catalog Number |
Pack Size |
Price (USD) |
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| KAT7 (MYST2), Active |
K316-380G-05 |
5 ug |
$235 |
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Add to Cart |
| KAT7 (MYST2), Active |
K316-380G-10 |
10 ug |
$345 |
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Add to Cart |
| KAT7 (MYST2), Active |
K316-380G-BULK |
BULK |
CONTACT US |
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* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Full-length recombinant human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
| Tag: |
GST tag |
| Expression System: |
Sf9 insect cells using baculovirus |
| Species: |
Human |
| Sequence: |
Full length |
| Genbank Number: |
NM_007067
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Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Acetyltransferase Assay
Molecular Weight: ~110 kDa
Gene Aliases: MYST2; HBO1; HBOA
Scientific Background: KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells (1). KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4 (2).
References:
1. Sharma, M. et.al: Androgen receptor interacts with a novel MYST protein, HBO1. J. Biol. Chem. 275: 35200-35208, 2000.
2. Iizuka, M. et.al: Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J. Biol. Chem. 274: 23027-23034, 1999.
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Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet. |
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. |
KAT7 (MYST2), Active Research Areas
The KAT7 (MYST2), Active product can be utilized in the following research areas, but not limited to:
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway