IL-2 Cell Signaling Reagents Growth Factors


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IL-2 (I862-40N)
Catalog Number Pack Size Price (USD)  
IL-2 I862-40N-10 10 ug $185   IL-2 Add to Cart
IL-2 I862-40N-50 50 ug $295   IL-2 Add to Cart
IL-2 I862-40N-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Human active form IL-2 (21-153) was expressed in E. coli cells and purified by proprietary chromatographic techniques.
Tag:
Expression System: E.coli
Species: Human
Sequence: 21-153
Genbank Number: NP_000577.2
   

Formulation: Recombinant protein stored in 1 X PBS, 10% glycerol.

Storage, Stability, and Shipping: Stored at desiccated below -20oC. It is stable at 4oC between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Cell Assay

Endotoxin Level: Less than 0.1 ng/µg (IEU/µg) of IL-2.

Molecular Weight: ~14.5 kDa

Gene Aliases: TCGF; lymphokine; IL2

Scientific Background: IL-2 or interleukin 2 is a secreted cytokine which referred to as T-cell growth factor, that is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. IL2 can act as a growth hormone that is important for the proliferation of T and B-lymphocytes (1). IL2 expression is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene (2).

References: 
1. Lowenthal, J. W. et.al: Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature 315: 669-672, 1985.

2. Hollander, G. A. et.al: Monoallelic expression of the interleukin-2 locus. Science 279: 2118-2121, 1998.



  Activity Assay:  Sample Biological Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




IL-2 Research Areas

The IL-2 product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway, JNK/SAPK Pathway, NfkB Pathway, p38 Pathway, PKA/PKC Pathway



IL-2 Related Products Found: Total 1 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Extracellular Ligands IL-8 (72AA) I868-40N Cell Assay View IL-8 (72AA)


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
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Antibodies
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Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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