Anti-PKC zeta Antibodies Primary Antibodies


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Anti-PKC zeta (P75-63R)
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Anti-PKC zeta P75-63R-100 100 ug $245   Anti-PKC zeta Add to Cart
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Product Data Sheet(s)




Description: Rabbit Polyclonal Antibody
References: 
1. Kim, SJ. Et al: Phorbol ester effects in atypical protein kinase C zeta overexpressing NIH3T3 cells: possible evidence for crosstalk between protein kinase C isoforms. Biochem Biophys Res Commun. 1997 Aug 18;237(2):336-9.

2. Romanelli, A. et al: p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex. Mol Cell Biol. 1999 Apr;19(4):2921-8.

Scientific Background: PKCζ is an atypical isoform of the PKC family. PKCζ is found in both particulate and soluble fractions and cannot be activated by phorbol ester. Overexpression of PKCζ and subsequent phorbol ester treatment abolished phorbol ester-induced reduction in cell proliferation (1). Overexpression of PKCζ also potentiates phorbol ester-induced mitogen-activated protein (MAP) kinase activation in a PKC-dependent manner. PKCζ is an upstream modulator of p70S6K, an important regulator of cell proliferation (2).

Host: Rabbit

Immunogen: Synthetic peptide corresponding to amino acids 408-412 (TSTFC) of human PKCζ

Formulation: PBS pH 7.4, 0.02% sodium azide, 50% glycerol

Purification: Affinity chromatography

Stability: Store at 4°C (add 0.1% NaN3) for several months, and at -20°C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Cited Applications: WB

Cross Reactivity: Western blot of human PKCζ

PKCζ from other species may also be detectable

Specificity: Recognizes the PKCζ protein



  Sample Data:  Representative western blot with Anti-PKCζ (1:1000) using 3 μg, 10 μg, and 30 μg of 3T6 cell lysate.




Anti-PKC zeta Research Areas

The Anti-PKC zeta product can be utilized in the following research areas, but not limited to:

Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway



Anti-PKC zeta Related Products Found: Total 20 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes PKC gamma, Active P66-10G Kinase Assay, Western Blot View PKC gamma, Active
Enzymes PKC beta I, Active P62-10G Kinase Assay, Western Blot View PKC beta I, Active
Enzymes PKC eta, Active P67-10G Kinase Assay, Western Blot View PKC eta, Active
Enzymes PKC delta, Active P64-10G Kinase Assay, Western Blot View PKC delta, Active
Enzymes PKC alpha, Active P61-18G Kinase Assay, Western Blot View PKC alpha, Active
Enzymes PKC beta II, Active P63-10G Kinase Assay, Western Blot View PKC beta II, Active
Signaling Reagents PKC Lipid Activator, 10x L51-39 Kinase Assay View PKC Lipid Activator, 10x
Signaling Reagents PKCtide P15-58 Kinase Assay View PKCtide
Enzymes PKC epsilon, Active P65-10G Kinase Assay, Western Blot View PKC epsilon, Active
Enzymes PKC mu, Active P72-10G Kinase Assay, Western Blot View PKC mu, Active
Enzymes PKC iota, Active P68-10G Kinase Assay, Western Blot View PKC iota, Active
Enzymes PKC nu, Active P73-10G Kinase Assay, Western Blot View PKC nu, Active
Enzymes PKC theta, Active P74-10G Kinase Assay, Western Blot View PKC theta, Active
Enzymes PKC zeta, Active P75-10G Kinase Assay, Western Blot View PKC zeta, Active
Antibodies Anti-PKC mu P72-63R WB View Anti-PKC mu
Enzymes PKC alpha, Active P61-10G Kinase Assay, Western Blot View PKC alpha, Active
Antibodies Anti-PKC theta P74-63R WB View Anti-PKC theta
Antibodies Anti-PKC delta P64-63R WB View Anti-PKC delta
Antibodies Anti-PKC delta/ theta P64-63DR WB View Anti-PKC delta/ theta
Antibodies Anti-PKC delta P64-63CR WB View Anti-PKC delta


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
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Extracellular Ligands Cytokines Cytokines
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Signaling Proteins
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Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
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Discovery Services
Compound Selective Profiling Compound Selective Profiling
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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