MST4 Active Enzymes Active Kinases


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MST4, Active (M59-10G)
Catalog Number Pack Size Price (USD)  
MST4, Active M59-10G-05 5 ug $205   MST4, Active Add to Cart
MST4, Active M59-10G-10 10 ug $295   MST4, Active Add to Cart
MST4, Active M59-10G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length human MST4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_016542
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~72kDa

Gene Aliases: MASK; RP6-213H19.1

Scientific Background: MST4 belongs to a family of proteins that share similarity with a budding yeast serine/threonine kinase, sterile-20 (Ste20), and have a role in mitogen-activated protein kinase signaling during cytoskeletal rearrangement, morphogenesis, apoptosis, and other diverse cellular events (1). Expression of MST4 has been shown to correlate with tumorigenicity and inversely with androgen receptor status in a number of human prostate cancer cell lines. Overexpression of MST4 induced anchorage-independent growth and increased in vitro proliferation of these prostate cancer cell lines (2).

References: 
1. Dan, I. Et al: Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties. J. Biol. Chem. 277: 5929-5939, 2002.

2. Sung, V. et al: The Ste20 kinase MST4 plays a role in prostate cancer progression. Cancer Res. 63: 3356-3363, 2003.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




MST4, Active Research Areas

The MST4, Active product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, JNK/SAPK Pathway, Neurobiology, Receptor Tyrosine Kinases



MST4, Active Related Products Found: Total 9 Related Products
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Enzymes MAPKAPK2, Active M40-11G Kinase Assay, Western Blot View MAPKAPK2, Active
Enzymes MAPKAPK3, Active M41-10G Kinase Assay, Western Blot View MAPKAPK3, Active
Enzymes MST1, Active S25-10G Kinase Assay, Western Blot View MST1, Active
Enzymes MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
Enzymes MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Enzymes MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Enzymes MAPKAPK2, Active M40-11H Kinase Assay, Western Blot View MAPKAPK2, Active
Antibodies Anti-MAPKAPK2/3 M40-63R WB View Anti-MAPKAPK2/3


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Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
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Extracellular Ligands
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Signaling Proteins
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Discovery Services
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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