LKB1(STK11) Protein Cell Signaling Reagents Cellular Proteins


Home › Cell Signaling Reagents - Cellular Proteins › LKB1(STK11) Protein

LKB1(STK11) Protein (L15-30G)
Catalog Number Pack Size Price (USD)  
LKB1(STK11) Protein L15-30G-20 20 ug $195 LKB1(STK11) Protein  40% OFF   LKB1(STK11) Protein Add to Cart
LKB1(STK11) Protein L15-30G-50 50 ug $395 LKB1(STK11) Protein  40% OFF   LKB1(STK11) Protein Add to Cart
LKB1(STK11) Protein L15-30G-BULK BULK CONTACT US  
* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.

Bulk Pricing for LKB1(STK11) Protein

Product Data Sheet(s)




Description: Recombinant full-length human LKB1(STK11) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_000455
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~85 kDa

Gene Aliases: STK11, LKB1, PJS

Scientific Background: LKB1(STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly maintaining energy homeostasis in hematopoietic cells through a novel metabolic checkpoint (1). STK11 serves as an essential regulator of HSCs and hematopoiesis, and more generally, points to the critical importance of coupling energy metabolism and stem cell homeostasis (2).

References: 
1. Gurumurthy, S. et.al: The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468: 659-663, 2010. Note: Erratum: Nature 476: 114 only, 2011.

2. Gan, B.et.al: Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468: 701-704, 2010.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




LKB1(STK11) Protein Research Areas

The LKB1(STK11) Protein product can be utilized in the following research areas, but not limited to:

Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, Ser/Thr Kinases



LKB1(STK11) Protein Related Products Found: Total 28 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes AKT3, Active A18-10G Kinase Assay, Western Blot View AKT3, Active
Enzymes AURORA A, Active A28-10G Kinase Assay, Western Blot View AURORA A, Active
Enzymes AURORA A, Active A28-18G Kinase Assay, Western Blot View AURORA A, Active
Enzymes AURORA B, Active A31-10G Kinase Assay, Western Blot View AURORA B, Active
Enzymes AURORA C, Active A33-10G Kinase Assay, Western Blot View AURORA C, Active
Enzymes CAMK1 beta, Active C08-10G Kinase Assay, Western Blot View CAMK1 beta, Active
Enzymes CDK7/Cyclin H1/MNAT1, Active C36-10H Kinase Assay, Western Blot View CDK7/Cyclin H1/MNAT1, Active
Enzymes FLT3, Active F12-11G Kinase Assay, Western Blot View FLT3, Active
Enzymes LOK, Active S29-11G Kinase Assay, Western Blot View LOK, Active
Enzymes MSSK1, Active S41-10G Kinase Assay, Western Blot View MSSK1, Active
Enzymes MST1, Active S25-10G Kinase Assay, Western Blot View MST1, Active
Enzymes MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
Enzymes NDR, Active S49-10G Kinase Assay, Western Blot View NDR, Active
Enzymes NDR2, Active S50-10G Kinase Assay, Western Blot View NDR2, Active
Enzymes p70S6K, Active R21-10H Kinase Assay, Western Blot View p70S6K, Active
Enzymes p70S6Kb, Active R22-10G Kinase Assay, Western Blot View p70S6Kb, Active
Enzymes PAK3, Active P04-10G Kinase Assay, Western Blot View PAK3, Active
Enzymes PASK, Active P08-11G Kinase Assay, Western Blot View PASK, Active
Enzymes SLK, Active S11-10G Kinase Assay, Western Blot View SLK, Active
Enzymes SOK1, Active S43-10G Kinase Assay, Western Blot View SOK1, Active
Enzymes STK3, Active S24-10G Kinase Assay, Western Blot View STK3, Active
Enzymes STK32B (YANK2), Active Y04-10G Kinase Assay, Western Blot View STK32B (YANK2), Active
Enzymes STK32C (YANK3), Active Y05-11G Kinase Assay, Western Blot View STK32C (YANK3), Active
Enzymes STK33, Active S46-10G Kinase Assay, Western Blot View STK33, Active
Enzymes STK39 (STLK3), Active S51-10H Kinase Assay, Western Blot View STK39 (STLK3), Active
Enzymes TSSK1B, Active S40-10BG Kinase Assay, Western Blot View TSSK1B, Active
Enzymes TSSK2, Active S38-10G Kinase Assay, Western Blot View TSSK2, Active
Signaling Reagents LKBtide L15-58 Kinase Assay View LKBtide


Items in Your Cart (0)
Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




Keep in touch, join us on:
LKB1(STK11) Protein Cell Signaling Reagents Cellular Proteins    LKB1(STK11) Protein Cell Signaling Reagents Cellular Proteins    LKB1(STK11) Protein Cell Signaling Reagents Cellular Proteins