RSK1 Active Enzymes Active Kinases


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RSK1, Active (R15-10G)
Catalog Number Pack Size Price (USD)  
RSK1, Active R15-10G-05 5 ug $205   RSK1, Active Add to Cart
RSK1, Active R15-10G-10 10 ug $295   RSK1, Active Add to Cart
RSK1, Active R15-10G-BULK BULK CONTACT US  
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Product Data Sheet(s)




Description: Recombinant full-length human RSK1 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_002953
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~108 kDa

Gene Aliases : RPS6KA1; HU-1; MAPKAPK1A; S6K-alpha 1

Scientific Background: RSK1 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. RSK1 encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. RSK1 transcript is present in lymphocytes, skeletal muscle, liver, and adipose tissue (1). RSKs are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation (2).

References: 
1. Moller, D E. et al: Human rsk isoforms: cloning and characterization of tissue-specific expression. Am. J. Physiol. 266: C351-C359, 1994.

2. Gross, S D. et al: Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90(Rsk). Science 286: 1365-1367, 1999.



  Specific Activity:  Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




RSK1, Active Research Areas

The RSK1, Active product can be utilized in the following research areas, but not limited to:

Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Inflammation, Neurobiology, NfkB Pathway, Ser/Thr Kinases



RSK1, Active Related Products Found: Total 21 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Signaling Proteins ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Signaling Reagents Kinase Assay Buffer I K01-09 Kinase Assay View Kinase Assay Buffer I
Enzymes RSK2, Active R17-10G Kinase Assay, Western Blot View RSK2, Active
Signaling Reagents RSK Substrate S06-58 Kinase Assay View RSK Substrate
Enzymes PDK1, Active P14-10H Kinase Assay, Western Blot View PDK1, Active
Enzymes RSK3, Active R16-10G Kinase Assay, Western Blot View RSK3, Active
Enzymes HER2, Active E27-11G Kinase Assay, Western Blot View HER2, Active
Enzymes MEK1 (EE), Active M02-12G Kinase Assay, Western Blot View MEK1 (EE), Active
Enzymes MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Enzymes HER4, Active E29-11G Kinase Assay, Western Blot View HER4, Active
Signaling Proteins ELK1 Protein E64-30G Kinase Assay, Western Blot View ELK1 Protein
Enzymes RSK4, Active R20-10G Kinase Assay, Western Blot View RSK4, Active
Antibodies Anti-RSK1 R15-63R WB View Anti-RSK1
Enzymes MSK1, Active R19-10G Kinase Assay, Western Blot View MSK1, Active
Enzymes MAPKAPK5, Active M42-10G Kinase Assay, Western Blot View MAPKAPK5, Active
Antibodies Anti-RSK (pan) R15-63BR WB View Anti-RSK (pan)
Enzymes MSK2, Active R18-10G Kinase Assay, Western Blot View MSK2, Active


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Product Types
Enzymes
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Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
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Signaling Proteins Cellular Proteins Cellular Proteins
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Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
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Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
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Signaling Reagents
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Signaling Reagents Oligo Substrates Oligo Substrates
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Antibodies
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Antibodies Modification Antibodies Modification Antibodies
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Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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