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Catalog Number |
Pack Size |
Price (USD) |
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| KAT4 Protein |
K313-31G-20 |
20 ug |
$195 40% OFF |
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Add to Cart |
| KAT4 Protein |
K313-31G-50 |
50 ug |
$395 40% OFF |
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Add to Cart |
| KAT4 Protein |
K313-31G-BULK |
BULK |
CONTACT US |
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* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Recombinant human KAT4 (1032-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
| Tag: |
GST tag |
| Expression System: |
Sf9 insect cells using baculovirus |
| Species: |
Human |
Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Western Blot
Molecular Weight: ~155 kDa
Gene Aliases: BA2R; CCG1; CCGS; DYT3; DYT3/TAF1; TAF1; N-TAF1; NSCL2; OF; P250; TAF2A
Scientific Background: KAT4 is a DNA-binding protein complex required for RNA polymerase II-mediated transcription of many, if not all, protein-encoding genes in eukaryotic cells. KAT4 plays a key role in the initiation process, since it binds to the TATA element to form a complex that nucleates the assembly of the other components into a preinitiation complex and that may be stable through multiple rounds of transcription. KAT4 may be targeted to specific chromatin-bound promoters and may play a key role in chromatin recognition (1). KAT4 also serves to link the control of transcription to the cell cycle (2).
References:
1. Jacobson, R. H. et.al: Structure and function of a human TAFII250 double bromodomain module. Science 288: 1422-1425, 2000.
2. Starr, D. B. et.al: TFIID binds in the minor groove of the TATA box. Cell 67: 1231-1240, 1991.
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. |
KAT4 Protein Research Areas
The KAT4 Protein product can be utilized in the following research areas, but not limited to:
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway
| Product Type |
Product Name |
Catalog Number |
Application |
Pack Sizes |
| Signaling Proteins |
KAT3A (CREBBP) Protein |
K312-31G |
Western Blot |
View KAT3A (CREBBP) Protein
|
| Signaling Proteins |
KAT3B (EP300) Protein |
K312-31BG |
Western Blot |
View KAT3B (EP300) Protein
|
| Signaling Proteins |
KAT8 (MYST1) Protein |
K317-31G |
Western Blot |
View KAT8 (MYST1) Protein
|
| Signaling Proteins |
KAT9 (ELP3) Protein |
K318-30G |
Western Blot |
View KAT9 (ELP3) Protein
|
| Signaling Proteins |
P300 Protein |
P07-31G |
Western Blot |
View P300 Protein
|
| Signaling Proteins |
PCAF Protein |
P09-31G |
Western Blot |
View PCAF Protein
|
| Enzymes |
KAT7 (MYST2), Active |
K316-380G |
Acetyltransferase Assay |
View KAT7 (MYST2), Active
|
| Enzymes |
KAT2A (GCN5), Active |
K311-381G |
Acetyltransferase Assay |
View KAT2A (GCN5), Active
|
| Enzymes |
KAT2B (PCAF), Active |
K311-381BG |
Acetyltransferase Assay |
View KAT2B (PCAF), Active
|
| Enzymes |
KAT5 (TIP60), Active |
K314-380G |
Acetyltransferase Assay |
View KAT5 (TIP60), Active
|
| Enzymes |
KAT6B (MYST4), Active |
K315-381BG |
Acetyltransferase Assay |
View KAT6B (MYST4), Active
|