SMYD3 Protein Signaling Proteins Acetyl/Methyltransferase Proteins


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SMYD3 Protein (S348-30CG)
Catalog Number Pack Size Price (USD)  
SMYD3 Protein S348-30CG-20 20 ug $195 SMYD3 Protein  40% OFF   SMYD3 Protein Add to Cart
SMYD3 Protein S348-30CG-50 50 ug $395 SMYD3 Protein  40% OFF   SMYD3 Protein Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human SMYD3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: BC031010
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Western Blot

Molecular Weight: ~71 kDa

Gene Aliases: ZMYND1; ZNFN3A1; FLJ21080

Scientific Background: SMYD3 (SET and MYND domain containing 3) is a histone methyltransferase that plays a role in transcriptional regulation as a member of an RNA polymerase complex. The introduction of SMYD3 enhanced cell growth and the histone methyltransferase activity of SMYD3 involved in the proliferation of cancer cells (1). A variable number of tandems repeat polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers (2).

References: 
1. Hamamoto, R. et.al: SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biol. 6: 731-740, 2004.

2. Tsuge, M. et.al: A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers. Nature Genet. 37: 1104-1107, 2005.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




SMYD3 Protein Research Areas

The SMYD3 Protein product can be utilized in the following research areas, but not limited to:

Cancer, Cell Cycle, Neurobiology



SMYD3 Protein Related Products Found: Total 11 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Proteins SMYD2 Protein S348-31BG Western Blot View SMYD2 Protein
Antibodies Anti-Methylated Lysine (Tri- epsilon-N-methyl) L95-67R WB, ELISA, IHC, IF, IP View Anti-Methylated Lysine (Tri- epsilon-N-methyl)
Antibodies Anti-Methylated Lysine (Tri- epsilon-N-methyl), Biotin Conjugated L95-67BR WB, ELISA, IHC, IF View Anti-Methylated Lysine (Tri- epsilon-N-methyl), Biotin Conjugated
Antibodies Anti-Methylated Lysine (Tri- epsilon-N-methyl), FITC Conjugated L95-67CR For direct immunofluorescence assay View Anti-Methylated Lysine (Tri- epsilon-N-methyl), FITC Conjugated
Antibodies Anti-Methylated Lysine (Tri- epsilon-N-methyl), HRP Conjugated L95-67DR WB, ELISA, IP, IHC, IF View Anti-Methylated Lysine (Tri- epsilon-N-methyl), HRP Conjugated
Signaling Reagents Histone H3 Peptide (1-21) H12-58 Acetylation/Methylation Assays View Histone H3 Peptide (1-21)
Signaling Proteins PRMT5 Protein P365-30EG Western Blot View PRMT5 Protein
Signaling Proteins SUV39H1 Protein S350-30G Western Blot View SUV39H1 Protein
Signaling Proteins SETD8 Protein S345-30G Western Blot View SETD8 Protein
Signaling Proteins SETDB2 Protein S346-30BG Western Blot View SETDB2 Protein
Signaling Proteins SETMAR Protein S347-30G Western Blot View SETMAR Protein


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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