14-3-3 epsilon Protein Signaling Proteins Cell Stress & Chaperone Proteins


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14-3-3 epsilon Protein (Y75-30N)
Catalog Number Pack Size Price (USD)  
14-3-3 epsilon Protein Y75-30N-20 20 ug $145 14-3-3 epsilon Protein  40% OFF   14-3-3 epsilon Protein Add to Cart
14-3-3 epsilon Protein Y75-30N-50 50 ug $305 14-3-3 epsilon Protein  40% OFF   14-3-3 epsilon Protein Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human tag-free 14-3-3epsilon was expressed in E. coli.
Tag: tag-free
Expression System: E.coli
Species: Human
Sequence: Full length
Genbank Number: NM_006761
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles

Applications: Western Blot

Molecular Weight: ~30kDa

Gene Aliases : 14-3-3 epsilon, YWHAE, MDS, MDCR, KCIP-1, 14-3-3E, FLJ45465

Scientific Background: 14-3-3ε, also known as tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein is a member of the 14-3-3 family. 14-3-3ε has been reported to be involved in heat shock transcription factor 1 (HSF1) and extracellular signal regulated protein kinase (ERK) pathways (1). 14-3-3ε interaction with the deubiquitinating enzyme UBPY, also known as USP8, regulates cargo sorting and membrane traffic at early endosomes. Association of 14-3-3ε, HSF1 with ERK during heat shock may modulate the amplitude of the response and control the termination of HSP expression on resumption of growth conditions (2).

References: 
1. Wang, X. et al: Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress.J. Biol. Chem. 2004; 279(47):49460-9.

2. Mizuno, E. et al: 14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.Exp Cell Res. 2007; 313(16):3624-34.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




14-3-3 epsilon Protein Research Areas

The 14-3-3 epsilon Protein product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, Cancer, Cell Cycle, Cellular Stress, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, WNT Signaling



14-3-3 epsilon Protein Related Products Found: Total 16 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Proteins 14-3-3 sigma Protein Y86-30N Western Blot View 14-3-3 sigma Protein
Signaling Proteins 14-3-3 alpha/beta Protein Y71-30N Western Blot View 14-3-3 alpha/beta Protein
Signaling Proteins 14-3-3 alpha/beta Protein Y71-30G Western Blot View 14-3-3 alpha/beta Protein
Signaling Proteins 14-3-3 epsilon Protein Y75-30G Western Blot View 14-3-3 epsilon Protein
Signaling Proteins 14-3-3 theta Protein Y84-30G Western Blot View 14-3-3 theta Protein
Signaling Proteins 14-3-3 theta Protein Y84-30N Western Blot View 14-3-3 theta Protein
Signaling Proteins 14-3-3 sigma Protein Y86-30G Western Blot View 14-3-3 sigma Protein
Signaling Proteins 14-3-3 zeta Protein Y92-30G Western Blot View 14-3-3 zeta Protein
Signaling Proteins 14-3-3 zeta Protein Y92-30N Western Blot View 14-3-3 zeta Protein
Signaling Proteins HSF1 Protein H25-30G Kinase Assay, Western Blot View HSF1 Protein
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Enzymes ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Enzymes MARK1, Active M43-10G Kinase Assay, Western Blot View MARK1, Active
Enzymes MARK3, Active M45-10G Kinase Assay, Western Blot View MARK3, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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