ARAF Protein Signaling Proteins Cellular Proteins
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ARAF Protein (A24-35G) |
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Product Data Sheet(s)
Description: Recombinant human ARAF (209-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
| Tag: | GST tag |
| Expression System: | Sf9 insect cells using baculovirus |
| Species: | Human |
| Sequence: | 209-end |
| Genbank Number: | NM_001654 |
Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Western Blot
Molecular Weight: ~70 kDa
Gene Aliases: PKS2, A-RAF, ARAF1, RAFA1
Scientific Background: ARAF belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. ARAF play a critical role in cell growth and development (1).The N-terminal regulatory domain of ARAF interacted with the putative mitochondrial proteins TOM and TIM44. ARAF is expressed predominantly in urogenital tissues (2). The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus.
References:
1. Huebner, K. et.al: Actively transcribed genes in the raf oncogene group, located on the X chromosome in mouse and human. Proc. Nat. Acad. Sci. 83: 3934-3938, 1986.
2. Lee, J.-E. et.al : The complete sequence and promoter activity of the human A-raf-1 gene (ARAF1). Genomics 20: 43-55, 1994.
Applications: Western Blot
Molecular Weight: ~70 kDa
Gene Aliases: PKS2, A-RAF, ARAF1, RAFA1
Scientific Background: ARAF belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. ARAF play a critical role in cell growth and development (1).The N-terminal regulatory domain of ARAF interacted with the putative mitochondrial proteins TOM and TIM44. ARAF is expressed predominantly in urogenital tissues (2). The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus.
References:
1. Huebner, K. et.al: Actively transcribed genes in the raf oncogene group, located on the X chromosome in mouse and human. Proc. Nat. Acad. Sci. 83: 3934-3938, 1986.
2. Lee, J.-E. et.al : The complete sequence and promoter activity of the human A-raf-1 gene (ARAF1). Genomics 20: 43-55, 1994.
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. | |
ARAF Protein Research Areas
The ARAF Protein product can be utilized in the following research areas, but not limited to:Cancer
Product Types
Enzymes
Active Acetyltransferases
Active Arginine Deiminases
Active Histone Deacetylases
Active Kinases
Active Methyltransferase
Active Phosphatases
Active Phosphodiesterases
Extracellular Ligands
Signaling Proteins
Acetyl/Methyltransferase Proteins
Adaptor Proteins
Apoptosis Proteins
Arginine Deiminases
Cell Cycle Proteins
Cell Stress & Chaperone Proteins
Cellular Proteins
Deacetylase/Demethylase Proteins
Fructose Kinase Proteins
G-Proteins
Lysyl Oxidase Proteins
Methylcytosine Dioxygenase Proteins
Microtubule/Actin Associated Proteins
Tau Proteins
Transcription Proteins
Ubiquitin Proteins
Unactive Kinases
Signaling Reagents
Antibodies
Isoform Specific Antibodies
Modification Antibodies
Phospho Specific Antibodies
Primary Antibodies
Secondary Antibodies
Tag Antibodies
Discovery Services
Research Categories
AKT/PKB Pathway
Angiogenesis
Apoptosis/Autophagy
Cancer
Cardiovascular Disease
Cell Cycle
Cellular Stress
Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway
Inflammation
Invasion/Metastasis
JAK/STAT Pathway
JNK/SAPK Pathway
Lipid Kinases
Metabolic Disorder
Neurobiology
NfkB Pathway
p38 Pathway
Phosphatases
Phosphodiesterases
PKA/PKC Pathway
Receptor Tyrosine Kinases
Ser/Thr Kinases
WNT Signaling
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