TAF1(C-term) Protein (T28-35BG)
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Catalog Number |
Pack Size |
Price (USD) |
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| TAF1(C-term) Protein |
T28-35BG-20 |
20 ug |
$195 40% OFF |
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Add to Cart |
| TAF1(C-term) Protein |
T28-35BG-50 |
50 ug |
$395 40% OFF |
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| TAF1(C-term) Protein |
T28-35BG-BULK |
BULK |
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* Prices listed in the "shopping cart" are not discount inclusive. Promotional Prices will be applied internally during the processing of orders and net totals adjusted accordingly.
Description: Recombinant human TAF1 (1032-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
| Tag: |
GST tag |
| Expression System: |
Sf9 insect cells using baculovirus |
| Species: |
Human |
Storage, Stability, and Shipping: Store product at –70
oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Applications: Western Blot
Molecular Weight: ~155 kDa
Gene Aliases: BA2R; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; N-TAF1; NSCL2; OF; P250; TAF2A
Scientific Background: TAF1 is a DNA-binding protein complex required for RNA polymerase II-mediated transcription of many, if not all, protein-encoding genes in eukaryotic cells. TAF1 plays a key role in the initiation process, since it binds to the TATA element to form a complex that nucleates the assembly of the other components into a preinitiation complex and that may be stable through multiple rounds of transcription. TAF1 may be targeted to specific chromatin-bound promoters and may play a key role in chromatin recognition (1). TAF1 also serves to link the control of transcription to the cell cycle (2).
References:
1. Jacobson, R. H. et.al: Structure and function of a human TAFII250 double bromodomain module. Science 288: 1422-1425, 2000.
2. Starr, D. B. et.al: TFIID binds in the minor groove of the TATA box. Cell 67: 1231-1240, 1991.
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Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. |
TAF1(C-term) Protein Research Areas
The TAF1(C-term) Protein product can be utilized in the following research areas, but not limited to:
Cell Cycle, Invasion/Metastasis