Storage, Stability, and Shipping
: Store product at –70o
C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
: Western Blot
: ~21 kDa
: UBC7; E217K; UBE2G
: UBE2G1 (UBC7) or ubiquitin-conjugating enzyme E2G 1 is a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins which are involved in degradation of muscle-specific proteins. UBC7 is highly expressed in skeletal muscle (1). UBC7 is involved in the selective ubiquitylation of different substrates by the same E3 complex (2).
1. Watanabe, T. K. et.al: Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans. Cytogenet. Cell Genet. 74: 146-148, 1996.
2. Shibata E. et.al: Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex. Mol Cell Biol, 2011 Aug.
||Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
The UBE2G1 (UBC7) Protein product can be utilized in the following research areas, but not limited to:
Cancer, Cell Cycle, Cytoplasmic Tyrosine Kinases, Neurobiology