AKT1 Unactive Signaling Proteins Unactive Kinases


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AKT1, Unactive (A16-14G)
Catalog Number Pack Size Price (USD)  
AKT1, Unactive A16-14G-20 20 ug $195 AKT1, Unactive  40% OFF   AKT1, Unactive Add to Cart
AKT1, Unactive A16-14G-50 50 ug $395 AKT1, Unactive  40% OFF   AKT1, Unactive Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human unactive AKT1 was expressed in Sf9 cells using an N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_005163
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~85 kDa

Gene Aliases: PKB; RAC; PRKBA; MGC99656; RAC-ALPHA

Scientific Background: AKT1/PKBα is a serine/threonine kinase that belongs to the AKT family. AKT1 is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility (1). AKT1 is frequently overexpressed and active in many types of human cancers including cancers of colon, breast, brain, pancreas and prostate as well as lymphomas and leukemias (2).

References: 
1. Coffer, PJ. et al: Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J. 1998 Oct 1; 335 (Pt 1): 1-13.

2. Anderson, KE. et al: Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr Biol. 1998 Jun 4;8(12): 684-91.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




AKT1, Unactive Research Areas

The AKT1, Unactive product can be utilized in the following research areas, but not limited to:

AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, Ser/Thr Kinases, WNT Signaling



AKT1, Unactive Related Products Found: Total 33 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes AKT1, Active A16-10G Kinase Assay, Western Blot View AKT1, Active
Enzymes AKT2, Active A17-10H Kinase Assay, Western Blot View AKT2, Active
Enzymes AKT3, Active A18-10G Kinase Assay, Western Blot View AKT3, Active
Enzymes GSK3 beta, Active G09-10G Kinase Assay, Western Blot View GSK3 beta, Active
Enzymes p70S6K, Active R21-10H Kinase Assay, Western Blot View p70S6K, Active
Signaling Proteins AKT3, Unactive A18-14G Kinase Assay, Western Blot View AKT3, Unactive
Enzymes AKT2, Active A17-10G Kinase Assay, Western Blot View AKT2, Active
Enzymes GSK3 alpha, Active G08-10G Kinase Assay, Western Blot View GSK3 alpha, Active
Enzymes AMPK (A1/B1/G1), Active P47-10H Kinase Assay, Western Blot View AMPK (A1/B1/G1), Active
Enzymes AMPK (A2/B1/G1), Active P48-10H Kinase Assay, Western Blot View AMPK (A2/B1/G1), Active
Signaling Reagents 4EBP1 Protein E35-54H Western Blot View 4EBP1 Protein
Signaling Proteins IkBA Protein I20-30G Kinase Assay, Western Blot View IkBA Protein
Enzymes AMPK (A1/B1/G2), Active P55-10H Kinase Assay, Western Blot View AMPK (A1/B1/G2), Active
Signaling Proteins IkBA Protein I20-31G Kinase Assay, Western Blot View IkBA Protein
Enzymes GSK3 beta, Active G09-10H Kinase Assay, Western Blot View GSK3 beta, Active
Enzymes AMPK (A1/B1/G3), Active P56-10H Kinase Assay, Western Blot View AMPK (A1/B1/G3), Active
Enzymes AMPK (A1/B2/G1), Active P50-10H Kinase Assay, Western Blot View AMPK (A1/B2/G1), Active
Signaling Proteins BAX Protein B14-30G Western Blot View BAX Protein
Signaling Proteins Ubiquitin Protein U06-54H Western Blot View Ubiquitin Protein
Signaling Proteins AKT2, Unactive A17-15H Kinase Assay, Western Blot View AKT2, Unactive
Enzymes p70S6Kb, Active R22-10G Kinase Assay, Western Blot View p70S6Kb, Active
Signaling Proteins p70S6Kb, Unactive R22-14G Kinase Assay, Western Blot View p70S6Kb, Unactive
Antibodies Anti-AKT1 A16-60M WB View Anti-AKT1
Signaling Proteins BID Protein B59-30G Western Blot View BID Protein
Signaling Proteins IkBB Protein I21-30G Kinase Assay, Western Blot View IkBB Protein
Enzymes PI3K (p110 alpha/p85 alpha), Active P27-18H Kinase Assay, Western Blot View PI3K (p110 alpha/p85 alpha), Active
Enzymes PI3K (p110 beta/p85 alpha), Active P28-10H Kinase Assay, Western Blot View PI3K (p110 beta/p85 alpha), Active
Signaling Proteins PTEN Protein P23-34G Western Blot View PTEN Protein
Antibodies Anti-AKT (pan) A16-63R WB View Anti-AKT (pan)
Signaling Proteins AKT2, Unactive A17-14G Kinase Assay, Western Blot View AKT2, Unactive
Signaling Proteins RAC3 Protein R02-30H Kinase Assay, Western Blot View RAC3 Protein
Signaling Reagents Modified AKT Substrate A05-58B Kinase Assay View Modified AKT Substrate
Antibodies Anti-AKT (pan) A16-63BR WB View Anti-AKT (pan)


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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