ERK1 Unactive Signaling Proteins Unactive Kinases


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ERK1, Unactive (M29-14G)
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ERK1, Unactive M29-14G-20 20 ug $195 ERK1, Unactive  40% OFF   ERK1, Unactive Add to Cart
ERK1, Unactive M29-14G-50 50 ug $395 ERK1, Unactive  40% OFF   ERK1, Unactive Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human ERK1 was expressed in E. coli cells using an N-terminal GST tag.
Tag: GST tag
Expression System: E.coli
Species: Human
Sequence: Full length
Genbank Number: NM_002746
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~70 kDa

Gene Aliases : MAPK3; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; MGC20180

Scientific Background: ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines (1). Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

References: 
1. Boulton, T G. et al: Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase. Biochemistry. 1991 Jan 8;30(1):278-86.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




ERK1, Unactive Research Areas

The ERK1, Unactive product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases



ERK1, Unactive Related Products Found: Total 14 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Proteins ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Enzymes ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Antibodies Anti-ERK1 M29-60CM IP View Anti-ERK1
Antibodies Anti-ERK2 M28-63R WB View Anti-ERK2
Antibodies Anti-ERK1 M29-60M WB, IP View Anti-ERK1
Antibodies Anti-ERK1/2 M29-60EM WB View Anti-ERK1/2
Antibodies Anti-ERK1 M29-60BM WB, IP View Anti-ERK1
Signaling Proteins p38 gamma, Unactive M37-14G Kinase Assay, Western Blot View p38 gamma, Unactive
Enzymes EPHB2, Active E22-11G Kinase Assay, Western Blot View EPHB2, Active
Enzymes ERK1, Active M29-10G Kinase Assay, Western Blot View ERK1, Active
Enzymes ERK5, Active M32-10G Kinase Assay, Western Blot View ERK5, Active


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Product Types
Enzymes
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Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
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Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
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Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
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Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
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Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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