JNK2 Unactive Signaling Proteins Unactive Kinases


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JNK2, Unactive (M34-14G)
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JNK2, Unactive M34-14G-20 20 ug $195 JNK2, Unactive  40% OFF   JNK2, Unactive Add to Cart
JNK2, Unactive M34-14G-50 50 ug $395 JNK2, Unactive  40% OFF   JNK2, Unactive Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length rat JNK2 was expressed in E. coli cells using an N-terminal GST tag.
Tag: GST tag
Expression System: E.coli
Species: Rat
Sequence: Full length
Genbank Number: NM_017322
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~74 kDa

Gene Aliases: SAPK; MAPK9

Scientific Background: JNK2 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation and treatment of cells with TNFα. JNK2 binds to the c-Jun transactivation domain and phosphorylates it on Ser-63 and Ser-73 (1). JNK2 has been shown to play an important role in disease processes. JNK2 plays a role in ventricular hypertrophy and is thought to be involved in hypertensive cardiac disease (2).

References: 
1. Sluss, H K. et al: Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol. 1994 Dec;14(12):8376-84.

2. Vogel, V. et al: Cardiac hypertrophy in the Prague-hypertensive rat is associated with enhanced JNK2 but not ERK tissue activity. Kidney Blood Press Res. 2001;24(1):52-6.



  Purity :  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




JNK2, Unactive Research Areas

The JNK2, Unactive product can be utilized in the following research areas, but not limited to:

Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases



JNK2, Unactive Related Products Found: Total 20 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Proteins c-JUN Protein J05-55G Kinase Assay, Western Blot View c-JUN Protein
Enzymes ASK1, Active M13-11G Kinase Assay, Western Blot View ASK1, Active
Enzymes JNK1, Active M33-10G Kinase Assay, Western Blot View JNK1, Active
Signaling Proteins JNK1, Unactive M33-14G Kinase Assay, Western Blot View JNK1, Unactive
Signaling Proteins JNK3, Unactive M35-14G Kinase Assay, Western Blot View JNK3, Unactive
Enzymes MST1, Active S25-10G Kinase Assay, Western Blot View MST1, Active
Enzymes MST3, Active S42-11G Kinase Assay, Western Blot View MST3, Active
Signaling Proteins ATF1 Protein A09-54G Kinase Assay, Western Blot View ATF1 Protein
Enzymes IRAK4, Active I12-10G Kinase Assay, Western Blot View IRAK4, Active
Signaling Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
Signaling Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
Enzymes TAOK1, Active T24-11G Kinase Assay, Western Blot View TAOK1, Active
Enzymes TAOK2, Active T25-11G Kinase Assay, Western Blot View TAOK2, Active
Enzymes MEKK2, Active M10-10G Kinase Assay, Western Blot View MEKK2, Active
Enzymes MEKK3, Active M11-10G Kinase Assay, Western Blot View MEKK3, Active
Antibodies Anti-JNK2 M34-60M WB, IP View Anti-JNK2
Antibodies Anti-JNK2/3 M34-63R WB View Anti-JNK2/3
Antibodies Anti-JNK1 M33-63R WB View Anti-JNK1
Enzymes JNK2, Active M34-10BG Kinase Assay, Western Blot View JNK2, Active
Enzymes JNK3, Active M35-10BG Kinase Assay, Western Blot View JNK3, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
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Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
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Signaling Reagents
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Antibodies
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Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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