p38 delta Unactive Signaling Proteins Unactive Kinases


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p38 delta, Unactive (M38-14G)
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p38 delta, Unactive M38-14G-20 20 ug $195 p38 delta, Unactive  40% OFF   p38 delta, Unactive Add to Cart
p38 delta, Unactive M38-14G-50 50 ug $395 p38 delta, Unactive  40% OFF   p38 delta, Unactive Add to Cart
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Product Data Sheet(s)




Description: Recombinant full-length human p38delta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Tag: GST tag
Expression System: Sf9 insect cells using baculovirus
Species: Human
Sequence: Full length
Genbank Number: NM_002754
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~65 kDa

Gene Aliases : SAPK4; PRKM13; MAPK13

Scientific Background: p38δ (SAPK4) is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines. P38δ has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines (1). MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase (2).

References: 
1. Goedert, M. et al: Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. EMBO J. 16: 3563-3571, 1997.

2. Kumar, S. et al: Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun. 1997 Jun 27;235(3):533-8.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




p38 delta, Unactive Research Areas

The p38 delta, Unactive product can be utilized in the following research areas, but not limited to:

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases



p38 delta, Unactive Related Products Found: Total 11 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Signaling Reagents ATF2 Protein A10-55G Kinase Assay, Western Blot View ATF2 Protein
Signaling Proteins p38 beta, Unactive M36-14G Kinase Assay, Western Blot View p38 beta, Unactive
Signaling Proteins p38 alpha, Unactive M39-14G Kinase Assay, Western Blot View p38 alpha, Unactive
Signaling Proteins p38 gamma, Unactive M37-14G Kinase Assay, Western Blot View p38 gamma, Unactive
Signaling Proteins SMAD2 Protein S11-30G Kinase Assay, Western Blot View SMAD2 Protein
Signaling Proteins SMAD3 Protein S12-30G Kinase Assay, Western Blot View SMAD3 Protein
Signaling Proteins TOPK, Unactive T14-14G Kinase Assay, Western Blot View TOPK, Unactive
Enzymes p38 alpha, Active M39-10BG Kinase Assay, Western Blot View p38 alpha, Active
Enzymes p38 beta, Active M36-10BG Kinase Assay, Western Blot View p38 beta, Active
Enzymes p38 gamma, Active M37-10BG Kinase Assay, Western Blot View p38 gamma, Active
Enzymes p38 delta, Active M38-10BG Kinase Assay, Western Blot View p38 delta, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
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Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
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Antibodies
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Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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