MBP Protein Signaling Reagents Protein Substrates


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MBP Protein (M42-51N)
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MBP Protein M42-51N 1 mg $45   MBP Protein Add to Cart
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Bulk Pricing for MBP Protein

Product Data Sheet(s)




Description: Native Swine MBP was extracted under acidic conditions and further purified by cation chromatography from pig brain (1). This product is routinely evaluated using active MAP Kinase 3/ERK1.
Tag:
Expression System:
Species: Swine
Sequence:
   
   

Storage, Stability, and Shipping: Store product at –20oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~21.5 kDa

Scientific Background: MBP exists as four major forms in the pig CNS with apparent molecular weights of 21.5K, 20.2K, 18.5K, and 17.3K (2). Native pig MBP is extracted under acidic conditions and further purified by cation chromatography. MBP is an efficient substrate for numerous protein kinases including ERK/MAP Kinase family, cAMP-dependent Protein Kinase, Calmodulin-dependent Protein Kinase, Protein Kinase C, and Phosphorylase Kinase (3, 4).

References: 
1. Chevalier D, et al. Purification of myelin basic protein from bovine brain. Protein Expr Purif. 18(2):229-34, 2000.

2. Sheng HZ, et al. Developmental study of myelin basic protein variants in various regions of pig nervous system. J Neurochem. 1989 Mar;52(3):736-40.

3. Sanghera J. et al. Identification of the sites in myelin basic protein that are phosphorylated by meiosis-activated protein kinase p44mpk. FEBS Lett. 1990 Oct 29;273(1-2):223-6.

4. Martenson, et al., Identification of multiple in vivo phosphorylation sites in rabbit myelin basic protein. J. Biol. Chem. 258: 930, 1983.



  Species Comparison:  Sample Protein comparison chart. For specific information on a given lot, see related technical data sheet.


  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




MBP Protein Research Areas

The MBP Protein product can be utilized in the following research areas, but not limited to:

ERK/MAPK Pathway, Neurobiology



MBP Protein Related Products Found: Total 26 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes CDK7/Cyclin H1/MNAT1, Active C36-10H Kinase Assay, Western Blot View CDK7/Cyclin H1/MNAT1, Active
Enzymes ERK2, Active M28-10G Kinase Assay, Western Blot View ERK2, Active
Signaling Proteins ERK2, Unactive M28-14G Kinase Assay, Western Blot View ERK2, Unactive
Signaling Proteins ERK2, Unactive M28-14U Kinase Assay, Western Blot View ERK2, Unactive
Enzymes ERK1, Active M29-10U Kinase Assay, Western Blot View ERK1, Active
Signaling Proteins ERK1, Unactive M29-14U Kinase Assay, Western Blot View ERK1, Unactive
Enzymes EIF2AK2, Active P80-11G Kinase Assay, Western Blot View EIF2AK2, Active
Enzymes MUSK, Active M60-11G Kinase Assay, Western Blot View MUSK, Active
Enzymes SRPK1, Active S21-10G Kinase Assay, Western Blot View SRPK1, Active
Enzymes ROR2, Active R13-11G Kinase Assay, Western Blot View ROR2, Active
Enzymes HIPK4, Active H06-10G Kinase Assay, Western Blot View HIPK4, Active
Enzymes TSSK2, Active S38-10G Kinase Assay, Western Blot View TSSK2, Active
Enzymes MEKK2, Active M10-10G Kinase Assay, Western Blot View MEKK2, Active
Enzymes MEKK3, Active M11-10G Kinase Assay, Western Blot View MEKK3, Active
Enzymes TOPK, Active T14-10G Kinase Assay, Western Blot View TOPK, Active
Enzymes SRPK2, Active S22-10G Kinase Assay, Western Blot View SRPK2, Active
Enzymes HIPK3, Active H05-13H Kinase Assay, Western Blot View HIPK3, Active
Enzymes CLK3, Active C60-10G Kinase Assay, Western Blot View CLK3, Active
Enzymes NEK3, Active N05-10G Kinase Assay, Western Blot View NEK3, Active
Enzymes MLK2, Active M18-11G Kinase Assay, Western Blot View MLK2, Active
Enzymes ERK5, Active M32-10G Kinase Assay, Western Blot View ERK5, Active
Enzymes MLK1, Active M17-11G Kinase Assay, Western Blot View MLK1, Active
Enzymes MLK3, Active M19-11G Kinase Assay, Western Blot View MLK3, Active
Enzymes NEK1, Active N02-11G Kinase Assay, Western Blot View NEK1, Active
Enzymes NEK5, Active N07-11G Kinase Assay, Western Blot View NEK5, Active
Enzymes STK36, Active S48-11G Kinase Assay, Western Blot View STK36, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
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Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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