MBP Protein Signaling Reagents Protein Substrates


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MBP Protein (M42-54G)
Catalog Number Pack Size Price (USD)  
MBP Protein M42-54G-20 20 ug $195   MBP Protein Add to Cart
MBP Protein M42-54G-50 50 ug $395   MBP Protein Add to Cart
MBP Protein M42-54G-BULK BULK CONTACT US  
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Bulk Pricing for MBP Protein

Product Data Sheet(s)




Description: Recombinant full length human MBP was expressed in E. coli cells using a N-terminal GST tag.
Tag: GST tag
Expression System: E.coli
Species: Human
Sequence: Full length
Genbank Number: NM_001025090
   

Storage, Stability, and Shipping: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications: Kinase Assay, Western Blot

Molecular Weight: ~36 kDa

Scientific Background: MBP or Myelin Basic Protein forms dimers across the cytoplasmic apposition during the formation of myelin. The region of the protein involved in folding, polymerization and substrate specificities is conserved in various species and it may have a specialized role in protein-lipid interactions in the myelin membrane (1). MBP is an efficient substrate for numerous protein kinases and share similarities with the MARCKS protein in terms of having extended conformations regulated by their environment, N-terminal modifications, a dual nature of interactions with lipids, and binding to actin and Ca2+-calmodulin (2).

References: 
1. Chapman, B.E. et al: Conformation of myelin basic protein and its role in myelin formation. Adv Exp Med Biol. 1978;100:207-20.

2. Harauz, G. et al: Analogous structural motifs in myelin basic protein and in MARCKS. Mol Cell Biochem.2000 Jun;209(1-2):155-63.



  Purity:  Sample Purity Data. For specific information on a given lot, see related technical data sheet.




MBP Protein Research Areas

The MBP Protein product can be utilized in the following research areas, but not limited to:

ERK/MAPK Pathway, Neurobiology



MBP Protein Related Products Found: Total 18 Related Products
Product Type Product Name Catalog Number Application Pack Sizes
Enzymes HIPK1, Active H03-11G Kinase Assay, Western Blot View HIPK1, Active
Enzymes ITK, Active I13-11G Kinase Assay, Western Blot View ITK, Active
Enzymes AURORA A, Active A28-10G Kinase Assay, Western Blot View AURORA A, Active
Enzymes AURORA A, Active A28-18G Kinase Assay, Western Blot View AURORA A, Active
Enzymes AURORA B, Active A31-10G Kinase Assay, Western Blot View AURORA B, Active
Enzymes KDR, Active K01-11G Kinase Assay, Western Blot View KDR, Active
Enzymes MNK2, Active M55-10G Kinase Assay, Western Blot View MNK2, Active
Enzymes MEK2, Active M03-10G Kinase Assay, Western Blot View MEK2, Active
Enzymes CLK1, Active C57-11G Kinase Assay, Western Blot View CLK1, Active
Enzymes AURORA C, Active A33-10G Kinase Assay, Western Blot View AURORA C, Active
Enzymes CLK2, Active C58-11G Kinase Assay, Western Blot View CLK2, Active
Enzymes DAPK1, Active D01-11G Kinase Assay, Western Blot View DAPK1, Active
Enzymes DAPK3, Active D03-10G Kinase Assay, Western Blot View DAPK3, Active
Enzymes MEK1, Active M02-10G Kinase Assay, Western Blot View MEK1, Active
Signaling Proteins TOPK, Unactive T14-14G Kinase Assay, Western Blot View TOPK, Unactive
Enzymes HIPK3, Active H05-13H Kinase Assay, Western Blot View HIPK3, Active
Enzymes CLK3, Active C60-10G Kinase Assay, Western Blot View CLK3, Active
Enzymes NEK3, Active N05-10G Kinase Assay, Western Blot View NEK3, Active


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Product Types
Enzymes
Enzymes Active Acetyltransferases Active Acetyltransferases
Enzymes Active Arginine Deiminases Active Arginine Deiminases
Enzymes Active Histone Deacetylases Active Histone Deacetylases
Enzymes Active Kinases Active Kinases
Enzymes Active Methyltransferase Active Methyltransferase
Enzymes Active Phosphatases Active Phosphatases
Enzymes Active Phosphodiesterases Active Phosphodiesterases
Extracellular Ligands
Extracellular Ligands Chemokines Chemokines
Extracellular Ligands Cytokines Cytokines
Extracellular Ligands Growth Factors Growth Factors
Signaling Proteins
Signaling Proteins Acetyl/Methyltransferase Proteins Acetyl/Methyltransferase Proteins
Signaling Proteins Adaptor Proteins Adaptor Proteins
Signaling Proteins Apoptosis Proteins Apoptosis Proteins
Signaling Proteins Arginine Deiminases Arginine Deiminases
Signaling Proteins Cell Cycle Proteins Cell Cycle Proteins
Signaling Proteins Cell Stress & Chaperone Proteins Cell Stress & Chaperone Proteins
Signaling Proteins Cellular Proteins Cellular Proteins
Signaling Proteins Deacetylase/Demethylase Proteins Deacetylase/Demethylase Proteins
Signaling Proteins Fructose Kinase Proteins Fructose Kinase Proteins
Signaling Proteins G-Proteins G-Proteins
Signaling Proteins Lysyl Oxidase Proteins Lysyl Oxidase Proteins
Signaling Proteins Methylcytosine Dioxygenase Proteins Methylcytosine Dioxygenase Proteins
Signaling Proteins Microtubule/Actin Associated Proteins Microtubule/Actin Associated Proteins
Signaling Proteins Tau Proteins Tau Proteins
Signaling Proteins Transcription Proteins Transcription Proteins
Signaling Proteins Ubiquitin Proteins Ubiquitin Proteins
Signaling Proteins Unactive Kinases Unactive Kinases
Signaling Reagents
Signaling Reagents Assay Reagents Assay Reagents
Signaling Reagents Oligo Substrates Oligo Substrates
Signaling Reagents Peptide Substrates Peptide Substrates
Signaling Reagents Protein Substrates Protein Substrates
Antibodies
Antibodies Isoform Specific Antibodies Isoform Specific Antibodies
Antibodies Modification Antibodies Modification Antibodies
Antibodies Phospho Specific Antibodies Phospho Specific Antibodies
Antibodies Primary Antibodies Primary Antibodies
Antibodies Secondary Antibodies Secondary Antibodies
Antibodies Tag Antibodies Tag Antibodies
Discovery Services
Compound Selective Profiling Compound Selective Profiling
Custom Protein Development Custom Protein Development

Research Categories
AKT/PKB Pathway AKT/PKB Pathway
Angiogenesis Angiogenesis
Apoptosis/Autophagy Apoptosis/Autophagy
Cancer Cancer
Cardiovascular Disease Cardiovascular Disease
Cell Cycle Cell Cycle
Cellular Stress Cellular Stress
Cytoplasmic Tyrosine Kinases Cytoplasmic Tyrosine Kinases
ERK/MAPK Pathway ERK/MAPK Pathway
Inflammation Inflammation
Invasion/Metastasis Invasion/Metastasis
JAK/STAT Pathway JAK/STAT Pathway
JNK/SAPK Pathway JNK/SAPK Pathway
Lipid Kinases Lipid Kinases
Metabolic Disorder Metabolic Disorder
Neurobiology Neurobiology
NfkB Pathway NfkB Pathway
p38 Pathway p38 Pathway
Phosphatases Phosphatases
Phosphodiesterases Phosphodiesterases
PKA/PKC Pathway PKA/PKC Pathway
Receptor Tyrosine Kinases Receptor Tyrosine Kinases
Ser/Thr Kinases Ser/Thr Kinases
WNT Signaling WNT Signaling




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