The COVID-19 outbreak due to the novel SARS-CoV-2 virus has turned into a global pandemic infecting hundred thousands of people worldwide. With a rapid rate of infection and a high mortality rate, it is estimated that the novel COVID-19 can infect millions of people all over the globe. Quick intervention at this stage to curb further spread becomes crucial and can only be achieved through expediting critical life science research. Scientists and clinicians around the world are focusing on understanding the molecular biology and mechanisms adapted by COVID-19, and its lethal mode of action. To understand the virus completely and develop safe therapeutic interventions, scientists require a range of trusted molecular biology reagents such as high-quality recombinant proteins related to SARS-CoV-2.
SignalChem, a global leader in cell signaling and protein engineering, has been devoting resources in creating and developing new research tools related to SARS-CoV-2 virus since the outbreak. With the help of advanced bioengineering technology to produce active proteins and AI drug development capability, we have already established expression systems for production of SARS-CoV-2 Spike proteins, RBD fragments, N protein, and other related protein products on a large scale to help detect IgG / IgM in potential patients. These proteins can be used as diagnostic standard antigens and can serve as targets of neutralizing antibodies under development and can also be used by scientists in their development of antibodies to detect SARS-CoV-2 virus in patients. In addition, SignalChem uses mammalian and insect cell expression systems in its production of these protein products as this is more immunogenic than the protein expressed from the E. coli system.
Name | Catalog Number | Activity | Species | Tag | Expression System | Sequence | Genbank Number |
2019-nCoV 3CLpro, Active | C19CL-G241H | Activity Assay | SARS-CoV-2 | HIS | E.coli | Full length | QHD43415 |
2019-nCoV NSP10/NSP16 Methyltransferase, Active | C19NS-E301H | Activity Assay | SARS-CoV-2 | HIS | E.coli | Full length | QHD43415 |
2019-nCoV NSP14 Methyltransferase, Active | C19NS-E311H | ELISA | SARS-CoV-2 | HIS | E.coli | 5925-6452 | QHD43415 |
2019-nCoV NSP7 Protein | C19N7-E541H | ELISA | Virus | HIS | E.coli | Full length | QHD43415 |
2019-nCoV NSP8 Protein | C19N8-E541H | ELISA | Virus | HIS | E.coli | Full length | QHD43415 |
2019-nCoV Nucleocapsid (N) Protein | C19NP-G242H | ELISA | SARS-CoV-2 | HIS | E.coli | Full length | QHD43423 |
2019-nCoV PLpro, Active | C19PL-G241H | Activity Assay, Inhibition Profile | SARS-CoV-2 | HIS | E.coli | 1564-1882 | QHD43415 |
2019-nCoV RdRp, Active | C19RP-G241H | Activity Assay | SARS-CoV-2 | HIS | E.coli | Full length | QHD43415 |
2019-nCoV Spike protein RBD, Fc Tag | C19SD-G241F | ELISA, FACS | SARS-CoV-2 | Fc | CHO cells | 319-541 | MN908947 |
2019-nCoV Spike protein RBD, HIS Tag | C19SD-G241H | ELISA, FACS | SARS-CoV-2 | HIS | CHO cells | 319-541 | MN908947 |
2019-nCoV Spike protein S1 (D614G) | C19S1-G231H | ELISA | Virus | HIS | CHO cells | 16-685 | MN908947 |
2019-nCoV Spike protein S1, Fc Tag | C19S1-G241F | FACS | SARS-CoV-2 | Fc | CHO cells | 16-685 | MN908947 |
2019-nCoV Spike protein S1, HIS Tag | C19S1-G241H | FACS | SARS-CoV-2 | HIS | CHO cells | 16-685 | MN908947 |
2019-nCoV Spike protein S2, Fc Tag | C19S2-G241F | ELISA | SARS-CoV-2 | Fc | CHO cells | 686-1212 | MN908947 |
2019-nCoV Spike RBD-N Protein Chimera | C19NSD-G242H | ELISA | SARS-CoV-2 | HIS | CHO cells | RBD (319-541) / N protein (237-419) | MN908947 |
ACE2 (18-615) Protein | A51C2-G342F | ELISA | Human | Fc | CHO cells | 18-615 | AF291820 |
ACE2 (18-739) Protein | A53C2-G341F | ELISA | Dog | Fc | CHO cells | 18-739 | XM_014111329 |
ACE2 (18-740) Protein | A52C2-G341F | ELISA | Rat | Fc | CHO cells | 18-740 | NM_001012006 |
ACE2 (19-740) Protein | A51C2-G341F | Activity Assay, ELISA | Human | Fc | CHO cells | 19-740 | AF291820 |
Anti 2019-nCoV N-Protein hIgG Antibody | C19NP-60H | ELISA, WB | Human, IgG1 | CHO cells | |||
Anti 2019-nCoV N-Protein hIgG Antibody, HRP conjugated | C19NP-60DH | ELISA, WB | Human, IgG1 | CHO cells | |||
Anti 2019-nCoV Spike Protein hIgA Antibody | C19S1-A60H | ELISA | Human, IgA | CHO cells | |||
Anti 2019-nCoV Spike Protein hIgG Antibody | C19S1-61H | ELISA, FACS | Human, IgG1 | CHO cells | |||
Anti 2019-nCoV Spike Protein hIgG Antibody | C19S1-60H | ELISA, WB | Human, IgG | CHO cells | |||
Anti 2019-nCoV Spike Protein hIgG Antibody, HRP conjugated | C19S1-60DH | ELISA | Human, IgG1 | CHO cells | |||
Anti 2019-nCoV Spike Protein hIgM Antibody | C19S1-M60H | ELISA | Human, IgM | CHO cells | |||
Anti 2019-nCoV Spike Protein Llama heavy-chain Antibody | C19S1-641HL | ELISA | Human, IgG | CHO cells | |||
Anti 2019-nCoV Spike Protein mIgG Antibody | C19S1-61MH | ELISA | Human Fab – Mouse IgG Fc | CHO cells | |||
Anti-Human IgA Antibody mIgG, Unconjugated | H38A-60M | ELISA | Mouse, IgG1 | ||||
Anti-Human IgG Antibody mIgM, Unconjugated | H38-60M | Mouse, IgM | |||||
Anti-Human IgM Antibody mIgG, Unconjugated | H38M-60M | Mouse, IgG | |||||
Cas12 (LbCpf1) Protein | C12CR-G241H | Lachnospiraceae | HIS | E.coli | 1-1227 | ATB19154 | |
Cas12 (LbCpf1) Protein | C12CR-G241G | Lachnospiraceae | GST | E.coli | 1-1227 | ATB19154 | |
Cas13a (LwC2c2) Protein | CS13A-E311 | Leptotrichia wadei | HIS | E.coli | 1-1152 | WP_021746774 | |
CD147 (22-205) Protein | C81D7-G651F | ELISA | Human | Fc | CHO cells | 22-205 | NM_198589 |
CD147 (22-205) Protein | C81D7-G651H | ELISA | Human | HIS | CHO cells | 22-205 | NM_198589 |
DPP4 (29-766) Protein | DP4CD-G441H | ELISA | Human | HIS | CHO cells | 29-766 | NM_001935 |
MERS Spike Protein RBD | MERSD-G241F | ELISA | MERS-CoV | Fc | CHO cells | 377-588 | KU696644 |
METTL16, Active | M336-380G | Activity Assay | Human | GST | Sf9 insect cells using baculovirus | Full length | NM_024086 |
METTL3/METTL14, Active | M323-380G | Activity Assay | Human | GST | Sf9 insect cells using baculovirus | Full Length | NM_019852 |
Proteinase K, Active (MBG) | P535-30N | Parengyodontium | Yeast cells | ||||
SARS-CoV Spike Protein RBD | SARSD-G241F | ELISA | SARS-CoV | Fc | CHO cells | 318-510 | AY278554 |
SARS-CoV Spike Protein S1, Fc Tag | SARS1-G241F | ELISA | SARS-CoV | Fc | CHO cells | 14-680 | AY278554 |
SARS-CoV Spike Protein S1, HIS Tag | SARS1-G241H | ELISA | SARS-CoV | HIS | CHO cells | 14-680 | AY278554 |
STAY CONNECTED
Fax: 1-604-232-4601