G Proteins, short for Guanine nucleotide-binding proteins, are a vital class of signaling molecules that play a central role in transmitting extracellular signals to the interior of cells. They act as molecular switches, converting information from various receptors on the cell surface to intracellular responses. G Proteins are involved in a wide range of physiological processes, including but not limited to cell growth, differentiation, metabolism, neurotransmission, immune response, and sensory perception. They are critical components of signal transduction pathways, which allow cells to respond appropriately to external stimuli and maintain homeostasis. Dysregulation of G Protein signaling has been implicated in numerous diseases, including cancer, cardiovascular disorders, neurological conditions, and metabolic disorders. Therefore, studying G proteins and their associated pathways is crucial for understanding disease mechanisms and identifying potential therapeutic targets.
Signalchem manufactures high-quality G proteins such as GTPases, ATPases, G protein alpha subunits, Ras, Rac, and Rho. We understand the importance of reliable research tools, and that’s why we ensure the utmost quality and performance of our G Protein products. With our dedication to customer satisfaction, you can trust that you are receiving proteins of the highest integrity and consistency, enabling you to achieve accurate and reproducible results.
Name | Catalog Number | Species | Tag | Expression System | Sequence | Genbank Number |
CDC42, Active | C108-310GH | Human | GST/HIS | E.coli | Full Length | NM_001791 |
GNAI1, Active | G121-310G | Human | GST | E.coli | 2-end | NM_002069 |
GNAI2, Active | G122-310G | Human | GST | E.coli | 2-end | NM_002070 |
GNAI3, Active | G123-310G | Human | GST | E.coli | 2-end | NM_006496 |
GNAS, Active | G127-310G | Human | GST | Sf9 insect cells using baculovirus | Full Length | NM_000516 |
HRAS (Mature form), Active | R105-310H | Human | HIS | E.coli | 2-186 | NM_005343 |
HRAS, Active (Biotinylated) | R105-310HB | Human | Avi-HIS | E.coli | 2-186 | NM_005343 |
KRAS (Isoform B), Active | R106B-311H | Human | HIS | E.coli | 1-169 | NM_004985 |
KRAS (Mature form), Active | R106-310H | Human | HIS | E.coli | 2-186 | NM_033360 |
KRAS (Mature form, Isoform B), Active | R106B-31H | Human | HIS | E.coli | 1-186 | NM_004985 |
KRAS, Active (Biotinylated) | R106-310HB | Human | Avi-HIS | E.coli | 2-186 | NM_033360 |
NRAS (Mature form), Active | R107-310H | Human | HIS | E.coli | 1-186 | NM_002524 |
NRAS, Active | R107-311H | Human | HIS | E.coli | 1-169 | NM_002524 |
NRAS, Active | R107-310AH | Human | Avi-HIS | E.coli | 1-186 | NM_002524 |
NRAS, Active (Biotinylated) | R107-31HB | Human | Avi-HIS | E.coli | 1-186 | NM_002524 |
NRAS, Active (Biotinylated) | R107-311HB | Human | Avi-HIS | E.coli | 1-169 | NM_002524 |
RAC1, Active | R103-310G | Human | GST | E.coli | Full Length | NM_006908 |
RAC2, Active | R104-310H | Human | HIS | E.coli | Full Length | NM_002872 |
RAC3, Active | R102-310H | Human | HIS | E.coli | Full Length | NM_005052 |
RhoA (Mature form), Active | R144-310H | Human | HIS | E.coli | 1-190 | NM_001664 |
RhoC (Mature form), Active | R144-310CH | Human | HIS | E.coli | 1-190 | NM_175744 |
RhoD (Mature form), Active | R144-310DH | Human | HIS | E.coli | 1-207 | BC001338 |
VCP, Active | V116-310G | Human | GST | Sf9 insect cells using baculovirus | Full Length | NM_007126 |
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