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K252B

Kinase inhibitor (pan)
Catalog No. K10-900E


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Catalog No. Pack Size Price (USD)
K10-900E-100 100 ug $127
K10-900E-1000 1 mg $512
K10-900E-BULK BULK Contact Us  


Overview:

Potent pan-specific protein kinase inhibitor: PKA (Ki = 90 nM), PKC (Ki = 20 nM), PKG (Ki = 100 nM) (1) as well as other kinases. Cell impermeable (2).

References:


1. H Kase et al. Biochem. Biophys. Res. Commun. 1987 142:436

2. K Makino et al. PLoS One 2012 7:e41049


CAS Registry Number:

99570-78-2


Molecular Formula:

C26H19N3O5


Appearance:

White to off-white powder


Melting Point:

N/A


Molecular Weight:

453.5


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (1 mg/ml); or DMF (1 mg/ml)


Aliases:

None


Storage and Stability:

Storage, Stability and Shipping


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, PKA/PKC Pathway, Receptor Tyrosine Kinases, Ser/Thr Kinases, WNT Signaling



SIGNALCHEM BIOTECH INC.


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