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Hypericin

PKC inhibitor
Catalog No. P61-900C


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Catalog No. Pack Size Price (USD)
P61-900C-01 1 mg $94
P61-900C-10 10 mg $875
P61-900C-BULK BULK Contact Us  


Overview:

Potent and selective inhibitor of protein kinase C (IC50 = 3.4 μM) (1). Displays antiviral activity (2). Induces apoptosis (3). Effects are light-dependent (4).

References:


1. I Takahashi et al. Biochem. Biophys. Res. Commun. 1989 165:1207

2. G Lavie et al. Med. Res. Rev. 1995 15:111

3. P Agostinis et al. Adv. Enzyme Regul. 2000 40:157

4. P. Miskovsky Curr. Drug Targets 2002 3:55


CAS Registry Number:

548-04-9


Molecular Formula:

C30H16O8


Appearance:

Dark brown to reddish-black powder


Melting Point:

N/A


Molecular Weight:

504.4


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml); or ethanol (5 mg/ml, warm)


Aliases:

1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro [1,10,9,8-opqra] perylene-7,14-dione


Storage and Stability:

Store desiccated as supplied at -20oC for up to 1 year. Store solutions at -20oC for up to 1 week.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases



SIGNALCHEM BIOTECH INC.


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