Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
B13-63R-100	100 ug	$595
B13-63R-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

B13-63R-100

100 ug

$595

B13-63R-BULK

BULK

Overview:

BRSK1 is serine/threonine kinases 1 which required for presynaptic differentiation in Caenorhabditis elegans that are needed for neuronal polarization (1). BRSK1 is highly expressed in all specific adult brain regions followed by fetal brain and adult spinal cord. It is also expressed in adult heart, pancreas, testis, ovary, lung, and kidney, and in fetal liver (2).

References:

1. Kishi, M. et.al: Mammalian SAD kinases are required for neuronal polarization. Science 307: 929-932, 2005.

2. Nagase, T.et.al: Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 8: 85-95, 2001.

Specificity:

Recognizes the BRSK1protein

Cross Reactivity:

Human, Mouse and Rat

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

BRSK1 antibody was raised against a 28 amino acid synthetic peptide from near the carboxy terminus of human BRSK1

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of BRSK1 in human brain tissue lysate with BRSK1 antibody at (A) 0.5 and (B) 1 ug/ml.