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Anti-BOK

Rabbit Polyclonal Antibody
Catalog No. B70-363R




Catalog No. Pack Size Price (USD)
B70-363R-100 100 ug $595
B70-363R-BULK BULK Contact Us  


References:


1. Lockshin RA et al: Cell death in the third millennium. Cell Death Differ. 2000; 7:2-7.

2. Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22:8590-607.

3. Hsu SY et al: bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Proc. Natl. Acad. Sci. USA 1997; 94:12401-6

4. Soleymanlou N et al: A novel Mtd splice isoform is responsible for trophoblast cell death in pre-eclampsia. Cell Death Differ. 2005; 12:441-52.


Specificity:

Recognizes the BOK protein. At least three isoforms of BOK are known to exist; this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members.


Cross Reactivity:

Human


Host / Isotype / Clone#:

Rabbit, IgG


Immunogen:

BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK


Purification:

Affinity chromatography


Stability:

Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Sample Data:

Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 ug/mL.



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer



SIGNALCHEM BIOTECH INC.


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