Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
K426-63BR-100	100 ug	$595
K426-63BR-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

K426-63BR-100

100 ug

$595

K426-63BR-BULK

BULK

References:

1. Lai F et al: cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics2000; 70:123-30.

2. Agger K et al: UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 2007; 449:731-4.

3. De Santa F et al: The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated silencing. Cell 2007; 130:1083-94

4. Sola S et al: p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One 2011; 6:e18421.

Specificity:

Recognizes the KDM6B protein

Cross Reactivity:

Human, Mouse and Rat

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

KDM6B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human KDM6B

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of KDM6B in K562 cell lysate with KDM6B antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.