Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
F17-63BR-100	100 ug	$595
F17-63BR-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

F17-63BR-100

100 ug

$595

F17-63BR-BULK

BULK

References:

1. Shamji AF et al: Integration of growth factor and nutrient signaling: implications for cancer biology. Mol. Cell 2003; 12:271-80.

2. Sabatini DM et al: RAFT1: a mammalian protein that binds to FKP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell 1994; 78:35-43.

3. Cardenas ME et al: Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin. Curr. Opin. Nephrol. Hypertens. 1995; 4:472-7.

4. Fingar DC et al: Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 2004; 23:3151-71.

Specificity:

Recognizes the mTOR protein

Cross Reactivity:

Human and Mouse

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

mTOR antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human mTOR

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of mTOR in L1210 cell lysate with mTOR antibody at (A) 1 and (B) 2 ug/mL.