Specificity:

Recognizes the PLAC4 protein

Cross Reactivity:

Human

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

PLAC4 antibody was raised against a 17 amino acid synthetic peptide near the center of human PLAC4

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of PLAC4 in human placenta tissue lysate with PLAC4 antibody at (A) 1 and (B) 2 ug/mL.

Sample Data:

Immunocytochemistry of PLAC4 in HeLa cells with PLAC4 antibody at 10 ug/mL.

References :

1. Kido S et al: D21S418E identifies a cAMP-regulated gene located on chromosome 21q22.3 that is expressed in placental syncytiotrophoblast and choriocarcinoma. Genomics1993; 17:256-9.

2. Lo YMD et al: Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat. Med.2007; 13:218-223.

3. Tsui NB et al: Synergy of total PLAC4 RNA concentration and measurement of the RNA single-nucleotide polymorphism allelic ratio for the noninvasive prenatal detection of trisomy 21. Clin. Chem.2010; 56:73-81.

4. Banzola I et al: PLAC4 and beta-HCG mRNA levels are not altered in the maternal circulation of pregnancies with trisomy 21. Prenat. Diagn.2008; 28:1262-7.